eflornithine has been researched along with Genetic Predisposition in 6 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| VanSickle, EA | 1 |
| Michael, J | 1 |
| Bachmann, AS | 1 |
| Rajasekaran, S | 1 |
| Prokop, JW | 1 |
| Kuzniecky, R | 1 |
| Hofstede, FC | 1 |
| Steindl, K | 1 |
| Rauch, A | 1 |
| Lipson, MH | 1 |
| Bupp, CP | 1 |
| Rial, NS | 2 |
| Meyskens, FL | 1 |
| Gerner, EW | 2 |
| Zell, JA | 1 |
| Cohen, AM | 1 |
| Montironi, R | 1 |
| Mazzucchelli, R | 1 |
| Marshall, JR | 1 |
| Bartels, PH | 1 |
| Krishnan, K | 1 |
| Ruffin, MT | 1 |
| Brenner, DE | 1 |
| Katdare, M | 1 |
| Kopelovich, L | 1 |
| Telang, N | 1 |
4 reviews available for eflornithine and Genetic Predisposition
| Article | Year |
|---|---|
Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
Topics: Adenomatous Polyposis Coli Protein; Animals; Clinical Trials as Topic; Eflornithine; Genetic Predisp | 2009 |
Clinical end points for developing pharmaceuticals to manage patients with a sporadic or genetic risk of colorectal cancer.
Topics: Adenomatous Polyposis Coli; Antineoplastic Agents; Chemoprevention; Clinical Trials as Topic; Colono | 2012 |
Prostate cancer prevention: review of target populations, pathological biomarkers, and chemopreventive agents.
Topics: Adenocarcinoma; Androgen Antagonists; Animals; Antineoplastic Agents; Clinical Trials as Topic; Diet | 1999 |
Chemoprevention for colorectal cancer.
Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Ap | 2000 |
2 other studies available for eflornithine and Genetic Predisposition
| Article | Year |
|---|---|
Expanding the phenotype: Four new cases and hope for treatment in Bachmann-Bupp syndrome.
Topics: Adolescent; Adult; Alopecia; Brain; Child; Child, Preschool; Developmental Disabilities; Dicarboxyli | 2021 |
Chemopreventive agents inhibit aberrant proliferation of the aneuploid phenotype in a colon epithelial cell line established from Apc 1638N [+/-] mouse.
Topics: Alitretinoin; Aneuploidy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; | 2001 |