eflornithine has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Though hyperglycemia has been considered as a fuel for growth of cancer cells, pathways leading to this condition are still under investigation." | 1.62 | Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase. ( Capellen, CC; Casero, RA; Chandra, S; Dunworth, M; Morwitzer, MJ; Ortega-Rodas, J; Tofilau, HMN, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Capellen, CC | 1 |
| Ortega-Rodas, J | 1 |
| Morwitzer, MJ | 1 |
| Tofilau, HMN | 1 |
| Dunworth, M | 1 |
| Casero, RA | 2 |
| Chandra, S | 1 |
| Geck, RC | 1 |
| Foley, JR | 1 |
| Murray Stewart, T | 1 |
| Asara, JM | 1 |
| Toker, A | 1 |
2 other studies available for eflornithine and ER-Negative PR-Negative HER2-Negative Breast Cancer
| Article | Year |
|---|---|
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase.
Topics: Breast Neoplasms; Eflornithine; Female; Humans; Hyperglycemia; Ornithine Decarboxylase; Ornithine De | 2021 |
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Topics: Biogenic Polyamines; Cell Line, Tumor; Cytotoxins; Eflornithine; Female; Humans; Neoplasm Proteins; | 2020 |