eflornithine has been researched along with Di Guglielmo Disease in 9 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clément, S | 1 |
| Delcros, JG | 1 |
| Feuerstein, BG | 1 |
| Nagasaki, T | 1 |
| Hino, M | 1 |
| Inaba, M | 1 |
| Nishizawa, Y | 1 |
| Morii, H | 1 |
| Otani, S | 1 |
| Choudhary, SK | 1 |
| Sharma, D | 1 |
| Dixit, A | 1 |
| Klinken, SP | 2 |
| Billelo, J | 1 |
| Bauer, S | 1 |
| Morse, HC | 2 |
| Thorgeirsson, SS | 2 |
| Holmes, KL | 1 |
| Meilhoc, E | 2 |
| Moutin, MJ | 2 |
| Romani, BH | 1 |
| Osborne, HB | 3 |
| Papazafiri, P | 1 |
| Watanabe, T | 1 |
| Shafman, T | 1 |
| Kufe, DW | 1 |
9 other studies available for eflornithine and Di Guglielmo Disease
| Article | Year |
|---|---|
Spermine uptake is necessary to induce haemoglobin synthesis in murine erythroleukaemia cells.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carrier Proteins; Drug Resistance; Eflornithin | 1995 |
Inhibition by 1alpha,25-dihydroxyvitamin D3 of activin A-induced differentiation of murine erythroleukemic F5-5 cells.
Topics: Acetyltransferases; Activins; Animals; Calcitriol; Cell Differentiation; Cell Division; Cell Line; C | 1997 |
D,L-alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, induces differentiation in MEL cells.
Topics: Animals; Cell Differentiation; Eflornithine; Enzyme Inhibitors; Friend murine leukemia virus; Leukem | 1999 |
Altered expression of beta-globin, transferrin receptor, and ornithine decarboxylase in Friend murine erythroleukemia cells inhibited by alpha-difluoromethylornithine.
Topics: Animals; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Eflornithine; Friend murine leukem | 1987 |
Transcriptional and post-transcriptional regulation of c-myc, c-myb, and p53 during proliferation and differentiation of murine erythroleukemia cells treated with DFMO and DMSO.
Topics: Animals; Blotting, Northern; Cell Count; Cell Cycle; Cell Differentiation; Cell Division; Dimethyl S | 1988 |
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dexamethasone; Eflornithine; Eryt | 1986 |
Effect of alpha-difluoromethylornithine on DNA methylation in murine erythroleukaemic cells. Relationship to stimulation of induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; DNA; Eflornithine; Leukemia, Erythroblas | 1987 |
Modulation of murine erythroleukemic cell differentiation by inhibitors of polyamine biosynthesis.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Depression, Chemical; Eflornith | 1987 |
Requirement of spermidine for induction of both heme synthesis and globin transcription in murine erythroleukemia cells.
Topics: Animals; Cell Division; Dexamethasone; Dimethyl Sulfoxide; Eflornithine; Globins; Heme; Leukemia, Er | 1985 |