eflornithine has been researched along with Delayed Effects, Prenatal Exposure in 6 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sparapani, M | 1 |
| Virgili, M | 1 |
| Caprini, M | 1 |
| Facchinetti, F | 1 |
| Ciani, E | 1 |
| Contestabile, A | 1 |
| Bell, JM | 3 |
| Whitmore, WL | 1 |
| Slotkin, TA | 4 |
| O'Toole, BA | 1 |
| Huffman, KW | 1 |
| Gibson, JP | 1 |
| Gray, JA | 1 |
| Rehnberg, BF | 1 |
| Rogers, EH | 1 |
| Lau, C | 1 |
| Kavlock, RJ | 1 |
| Madwed, DS | 1 |
6 other studies available for eflornithine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry.
Topics: Animals; Animals, Newborn; Body Weight; Brain Chemistry; Cerebellum; Choline O-Acetyltransferase; Ef | 1996 |
Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivity.
Topics: Aging; Animals; Body Weight; Brain; DNA; Eflornithine; Female; Injections, Subcutaneous; Nerve Tissu | 1986 |
Effects of eflornithine hydrochloride (DFMO) on fetal development in rats and rabbits.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Dose-Response Relationship, Drug; Eflor | 1989 |
Prenatal alpha-difluoromethylornithine treatment: effects on postnatal renal growth and function in the rat.
Topics: Analysis of Variance; Animals; Body Weight; Creatinine; Eflornithine; Female; Gestational Age; Kidne | 1989 |
Critical development periods for inhibition of ornithine decarboxylase by alpha-difluoromethylornithine: effects on ontogeny of sensorimotor behavior.
Topics: Animals; Behavior, Animal; Eflornithine; Female; Motor Activity; Nervous System; Ornithine Decarboxy | 1986 |
Polyamines as intermediates in developmental neurotoxic events.
Topics: Animals; Body Weight; Brain; Cell Division; DNA Replication; Eflornithine; Female; Organ Size; Ornit | 1986 |