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eflornithine and Conjunctivitis

eflornithine has been researched along with Conjunctivitis in 1 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Conjunctivitis: INFLAMMATION of the CONJUNCTIVA.

Research Excerpts

ExcerptRelevanceReference
" Chronic administration (52 weeks) by gavage to Charles River CD rats at dosages of 400, 800, and 1600 mg/kg produced weight loss, increased platelets, alopecia and skin abrasions, dermatitis, liver necrosis, and gastric inflammation."1.29Chronic toxicity studies of the potential cancer preventive 2-(difluoromethyl)-dl-ornithine. ( Boone, CW; Crowell, JA; Goldenthal, EI; Kelloff, GJ; Malone, WF, 1994)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crowell, JA1
Goldenthal, EI1
Kelloff, GJ1
Malone, WF1
Boone, CW1

Other Studies

1 other study available for eflornithine and Conjunctivitis

ArticleYear
Chronic toxicity studies of the potential cancer preventive 2-(difluoromethyl)-dl-ornithine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 22, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Blood Cell Count; Blood Chemical Analysis; Body Weight; Cell Divis

1994