eflornithine has been researched along with Cochlear Hearing Loss in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It causes a sensorineural hearing loss in humans." | 1.28 | An animal model of hearing loss from alpha-difluoromethylornithine. ( Brownell, WE; Jansen, C; Mattox, DE; Miller, KD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salzer, SJ | 1 |
| Mattox, DE | 2 |
| Brownell, WE | 2 |
| Jansen, C | 1 |
| Miller, KD | 1 |
2 other studies available for eflornithine and Cochlear Hearing Loss
| Article | Year |
|---|---|
Cochlear damage and increased threshold in alpha-difluoromethylornithine (DFMO) treated guinea pigs.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Auditory Threshold; Cochlea; Eflornithine; Guinea P | 1990 |
An animal model of hearing loss from alpha-difluoromethylornithine.
Topics: Animals; Brain Stem; Disease Models, Animal; Eflornithine; Guinea Pigs; Hair Cells, Auditory; Hearin | 1989 |