eflornithine has been researched along with Cocarcinogenesis in 4 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Cocarcinogenesis: The combination of two or more different factors in the production of cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, DFMO treatment led to marked hair loss in PKC epsilon transgenic mice." | 1.32 | Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. ( Ness, KJ; Oberley, TD; Verma, AK; Wheeler, DL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wheeler, DL | 1 |
| Ness, KJ | 1 |
| Oberley, TD | 1 |
| Verma, AK | 1 |
| Fong, LY | 1 |
| Pegg, AE | 1 |
| Magee, PN | 1 |
| Reiners, JJ | 1 |
| Pavone, A | 1 |
| Rupp, T | 1 |
| Cantu, AR | 1 |
| DiGiovanni, J | 1 |
| Kruszewski, FH | 1 |
| Chenicek, KJ | 1 |
4 other studies available for eflornithine and Cocarcinogenesis
| Article | Year |
|---|---|
Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.
Topics: Administration, Oral; Alopecia; Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma, Squamous Cell; | 2003 |
Alpha-difluoromethylornithine inhibits N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Biogenic Polyamines; Carcin | 1998 |
Modulation of the co-promoting activity of gamma interferon in SENCAR and C57BL/6 mouse skin by difluoromethylornithine and the scheduling and duration of interferon treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Eflornithine; Female; Interferon-gamma; | 1990 |
Modulation of chrysarobin skin tumor promotion.
Topics: Animals; Anthracenes; Carcinogens; Cocarcinogenesis; Eflornithine; Female; Fluocinolone Acetonide; M | 1988 |