eflornithine has been researched along with Cholera Infantum in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, and human leukocyte interferon (IFN-alpha) have synergistic anti-tumor activities in vivo in B 16 melanoma and in vitro against several human cancer cell lines." | 3.67 | Difluoromethylornithine and leukocyte interferon: a phase I study in cancer patients. ( Benjamin, R; Gutterman, J; Kantarjian, H; Plager, C; Quesada, J; Talpaz, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bespalov, VG | 1 |
| Aleksandrov, VA | 1 |
| Semenov, AL | 1 |
| Kovan'ko, EG | 1 |
| Ivanov, SD | 1 |
| Abeloff, MD | 1 |
| Rosen, ST | 1 |
| Luk, GD | 1 |
| Baylin, SB | 1 |
| Zeltzman, M | 1 |
| Sjoerdsma, A | 1 |
| Talpaz, M | 1 |
| Plager, C | 1 |
| Quesada, J | 1 |
| Benjamin, R | 1 |
| Kantarjian, H | 1 |
| Gutterman, J | 1 |
3 other studies available for eflornithine and Cholera Infantum
| Article | Year |
|---|---|
[Comparative effects of difluoromethylornithine and tincture of Siberian ginseng root on radiation carcinogenesis and life span in rats].
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Eflornithine; Eleutherococcus; Fema | 2012 |
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Colonic Neoplasms; Drug Evaluation; Eflornithine | 1986 |
Difluoromethylornithine and leukocyte interferon: a phase I study in cancer patients.
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Eflornithine; Female; Gastrointestinal Diseases | 1986 |