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eflornithine and Chagas Cardiomyopathy

eflornithine has been researched along with Chagas Cardiomyopathy in 1 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.

Research Excerpts

ExcerptRelevanceReference
"Nifurtimox is one of the two molecules used for treatment of Chagas disease."7.77[Nifurtimox, a bright future for treatment of Chagas disease]. ( Beranger, C; Boulliat, C; Coillot, C; Gaillard, K; Oliver, M; Rouault, M; Wolf, A, 2011)
"Nifurtimox is one of the two molecules used for treatment of Chagas disease."3.77[Nifurtimox, a bright future for treatment of Chagas disease]. ( Beranger, C; Boulliat, C; Coillot, C; Gaillard, K; Oliver, M; Rouault, M; Wolf, A, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wolf, A1
Boulliat, C1
Coillot, C1
Rouault, M1
Gaillard, K1
Beranger, C1
Oliver, M1

Other Studies

1 other study available for eflornithine and Chagas Cardiomyopathy

ArticleYear
[Nifurtimox, a bright future for treatment of Chagas disease].
    Medecine tropicale : revue du Corps de sante colonial, 2011, Volume: 71, Issue:2

    Topics: Chagas Cardiomyopathy; Chagas Disease; Drug Therapy, Combination; Eflornithine; Humans; Nifurtimox;

2011