eflornithine has been researched along with Chagas Cardiomyopathy in 1 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nifurtimox is one of the two molecules used for treatment of Chagas disease." | 7.77 | [Nifurtimox, a bright future for treatment of Chagas disease]. ( Beranger, C; Boulliat, C; Coillot, C; Gaillard, K; Oliver, M; Rouault, M; Wolf, A, 2011) |
| "Nifurtimox is one of the two molecules used for treatment of Chagas disease." | 3.77 | [Nifurtimox, a bright future for treatment of Chagas disease]. ( Beranger, C; Boulliat, C; Coillot, C; Gaillard, K; Oliver, M; Rouault, M; Wolf, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolf, A | 1 |
| Boulliat, C | 1 |
| Coillot, C | 1 |
| Rouault, M | 1 |
| Gaillard, K | 1 |
| Beranger, C | 1 |
| Oliver, M | 1 |
1 other study available for eflornithine and Chagas Cardiomyopathy
| Article | Year |
|---|---|
[Nifurtimox, a bright future for treatment of Chagas disease].
Topics: Chagas Cardiomyopathy; Chagas Disease; Drug Therapy, Combination; Eflornithine; Humans; Nifurtimox; | 2011 |