eflornithine has been researched along with Cerebral Infarction in 5 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Temiz, C | 1 |
| Dogan, A | 1 |
| Baskaya, MK | 1 |
| Dempsey, RJ | 2 |
| Schmitz, MP | 1 |
| Combs, DJ | 1 |
| Muszynski, CA | 1 |
| Robertson, CS | 1 |
| Goodman, JC | 1 |
| Henley, CM | 1 |
| Lukkarinen, JA | 1 |
| Kauppinen, RA | 1 |
| Gröhn, OH | 1 |
| Oja, JM | 1 |
| Sinervirta, R | 1 |
| Järvinen, A | 1 |
| Alhonen, LI | 1 |
| Jänne, J | 1 |
| Sauer, D | 1 |
| Martin, P | 1 |
| Allegrini, PR | 1 |
| Bernasconi, R | 1 |
| Amacker, H | 1 |
| Fagg, GE | 1 |
5 other studies available for eflornithine and Cerebral Infarction
| Article | Year |
|---|---|
Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion.
Topics: Animals; Brain Edema; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Dose | 2005 |
Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cats; Cerebral Infarction; Eflornithine; | 1993 |
DFMO reduces cortical infarct volume after middle cerebral artery occlusion in the rat.
Topics: Animals; Cerebral Arteries; Cerebral Infarction; Constriction; Eflornithine; Ischemic Attack, Transi | 1993 |
Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats.
Topics: Animals; Animals, Genetically Modified; Body Water; Brain; Cerebral Infarction; Eflornithine; Enzyme | 1998 |
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cerebral Infarction; Eflornithine; Magn | 1992 |