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eflornithine and Cell Transformation, Viral

eflornithine has been researched along with Cell Transformation, Viral in 6 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hölttä, E2
Vartio, T1
Jänne, J1
Vaheri, A1
Hovi, T1
Auvinen, M1
Andersson, LC1
Aman, P1
Oredsson, SM1
Heby, O1
Bachrach, U1
Shtorch, A1
McGovern, KA1
Clark, RS1
Pegg, AE1
Klinken, SP1
Castilla, MJ1
Thorgeirsson, SS1

Other Studies

6 other studies available for eflornithine and Cell Transformation, Viral

ArticleYear
Temperature-dependent and transformation-associated changes in polyamine metabolism in normal and Rous sarcoma virus-infected chick embryo fibroblasts.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Eflornithine; Fibroblasts;

1981
Polyamines are essential for cell transformation by pp60v-src: delineation of molecular events relevant for the transformed phenotype.
    The Journal of cell biology, 1993, Volume: 122, Issue:4

    Topics: Actin Cytoskeleton; Actins; Animals; Cell Line; Cell Transformation, Viral; Eflornithine; GTPase-Act

1993
Inhibition of polyamine synthesis in human B lymphocytes during primary infection with Epstein-Barr virus (EBV) blocks cellular DNA synthesis but not the expression of EBV-encoded nuclear antigens (EBNA).
    Biochemical and biophysical research communications, 1989, Mar-31, Volume: 159, Issue:3

    Topics: Antigens, Viral; B-Lymphocytes; Cell Line; Cell Transformation, Viral; Cells, Cultured; Child; DNA R

1989
Formation of cadaverine as an effect of alpha-difluoromethylornithine on chick embryo fibroblasts transformed by rous sarcoma virus.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Cadaverine; Cell Transformation, Neoplastic; Cell Transformation, Vi

1985
Effect of 1,3,6-triaminohexane and 1,4,7-triaminoheptane on growth and polyamine metabolism in SV-3T3 cells treated with 2-difluoromethylornithine.
    Journal of cellular physiology, 1986, Volume: 127, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Eflornithine; Fibroblasts; Heptanes;

1986
Effect of inhibitors of ornithine decarboxylase on retrovirus induced transformation of murine erythroid precursors in vitro.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Animals; Cell Division; Cell Transformation, Viral; Eflornithine; Erythrocytes; Erythropoietin; Hema

1986