eflornithine has been researched along with Carcinoma, Lewis Lung in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samoilenko, ОА | 1 |
| Milinevska, OA | 1 |
| Karnaushenko, OV | 1 |
| Shlyakhovenko, VA | 1 |
| Zaletok, SP | 1 |
| Chamaillard, L | 1 |
| Catros-Quemener, V | 1 |
| Delcros, JG | 1 |
| Bansard, JY | 1 |
| Havouis, R | 2 |
| Desury, D | 1 |
| Commeurec, A | 1 |
| Genetet, N | 1 |
| Moulinoux, JP | 2 |
| Douaud, F | 1 |
| Le Roch, N | 1 |
| Renault, J | 1 |
| Vaultier, M | 1 |
| Seiler, N | 1 |
3 other studies available for eflornithine and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
Topics: Animals; Arginase; Arginine; Carcinoma, Lewis Lung; Cell Line, Tumor; Drug Screening Assays, Antitum | 2015 |
Polyamine deprivation prevents the development of tumour-induced immune suppression.
Topics: Animals; Carcinoma, Lewis Lung; Dinoprostone; Eflornithine; Enzyme Inhibitors; Immune Tolerance; Int | 1997 |
Dimethylsilane polyamines: cytostatic compounds with potentials as anticancer drugs.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; CHO Cells; Cricetinae; DNA; Drug Screening As | 1997 |