eflornithine has been researched along with Carcinoma, Intraepithelial in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit." | 8.81 | Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001) |
| "Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit." | 4.81 | Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishioka, K | 1 |
| Melgarejo, AB | 1 |
| Lyon, RR | 1 |
| Mitchell, MF | 1 |
| Bacus, JW | 1 |
| Boone, CW | 1 |
| Bacus, JV | 1 |
| Follen, M | 1 |
| Kelloff, GJ | 1 |
| Kagan, V | 1 |
| Lippman, SM | 1 |
| Fabian, CJ | 1 |
| Kimler, BF | 1 |
1 review available for eflornithine and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention.
Topics: Aneuploidy; Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Aromatase Inhibitors; Breas | 2001 |
1 trial available for eflornithine and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Polyamines as biomarkers of cervical intraepithelial neoplasia.
Topics: Biogenic Polyamines; Biomarkers, Tumor; Carcinoma in Situ; Eflornithine; Female; Humans; Ornithine D | 1995 |
1 other study available for eflornithine and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Image morphometric nuclear grading of intraepithelial neoplastic lesions with applications to cancer chemoprevention trials.
Topics: Antineoplastic Agents; Biopsy; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell | 1999 |