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eflornithine and Carcinoma, Intraepithelial

eflornithine has been researched along with Carcinoma, Intraepithelial in 3 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit."8.81Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001)
"Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit."4.81Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishioka, K1
Melgarejo, AB1
Lyon, RR1
Mitchell, MF1
Bacus, JW1
Boone, CW1
Bacus, JV1
Follen, M1
Kelloff, GJ1
Kagan, V1
Lippman, SM1
Fabian, CJ1
Kimler, BF1

Reviews

1 review available for eflornithine and Carcinoma, Intraepithelial

ArticleYear
Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention.
    Annals of the New York Academy of Sciences, 2001, Volume: 952

    Topics: Aneuploidy; Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Aromatase Inhibitors; Breas

2001

Trials

1 trial available for eflornithine and Carcinoma, Intraepithelial

ArticleYear
Polyamines as biomarkers of cervical intraepithelial neoplasia.
    Journal of cellular biochemistry. Supplement, 1995, Volume: 23

    Topics: Biogenic Polyamines; Biomarkers, Tumor; Carcinoma in Situ; Eflornithine; Female; Humans; Ornithine D

1995

Other Studies

1 other study available for eflornithine and Carcinoma, Intraepithelial

ArticleYear
Image morphometric nuclear grading of intraepithelial neoplastic lesions with applications to cancer chemoprevention trials.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:12

    Topics: Antineoplastic Agents; Biopsy; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell

1999