eflornithine has been researched along with Carcinoma, Ductal, Pancreatic in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we tested DFMO in combination with a polyamine transport inhibitor (PTI), Trimer44NMe, against Gemcitabine-resistant PDAC cells." | 1.48 | Difluoromethylornithine Combined with a Polyamine Transport Inhibitor Is Effective against Gemcitabine Resistant Pancreatic Cancer. ( Altomare, DA; Copik, AJ; Gitto, SB; Hogan, FC; Oyer, JL; Pandey, V; Phanstiel, O, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nakkina, SP | 1 |
| Gitto, SB | 2 |
| Beardsley, JM | 1 |
| Pandey, V | 2 |
| Rohr, MW | 1 |
| Parikh, JG | 1 |
| Phanstiel, O | 2 |
| Altomare, DA | 2 |
| Oyer, JL | 1 |
| Copik, AJ | 1 |
| Hogan, FC | 1 |
| Mohammed, A | 1 |
| Janakiram, NB | 1 |
| Madka, V | 1 |
| Ritchie, RL | 1 |
| Brewer, M | 1 |
| Biddick, L | 1 |
| Patlolla, JM | 1 |
| Sadeghi, M | 1 |
| Lightfoot, S | 1 |
| Steele, VE | 1 |
| Rao, CV | 1 |
3 other studies available for eflornithine and Carcinoma, Ductal, Pancreatic
| Article | Year |
|---|---|
DFMO Improves Survival and Increases Immune Cell Infiltration in Association with MYC Downregulation in the Pancreatic Tumor Microenvironment.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Reg | 2021 |
Difluoromethylornithine Combined with a Polyamine Transport Inhibitor Is Effective against Gemcitabine Resistant Pancreatic Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biological Transport; Biosynthet | 2018 |
Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Proliferation; Disease Pro | 2014 |