eflornithine has been researched along with Carcinoma, Basal Cell, Pigmented in 6 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our intention was to retrospectively assess the further incidence of skin cancer, other malignancies, and adverse events of patients accrued to our phase III skin cancer prevention study of DFMO." | 2.77 | A phase III skin cancer chemoprevention study of DFMO: long-term follow-up of skin cancer events and toxicity. ( Bailey, HH; Borich, A; Havighurst, T; Kim, K; Kreul, SM; Mendonça, EA; Snow, S; Verma, A; Wood, GS, 2012) |
| "Subjects with a history of skin cancer taking daily DFMO had an insignificant reduction (P = 0." | 2.75 | A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancer. ( Bailey, HH; Berg, ER; Carbone, PP; Douglas, J; Dreckschmidt, NE; Hamielec, M; Havighurst, TC; Kim, K; Larson, PO; Lenaghan, T; Pomplun, M; Puchalsky, D; Sharata, HH; Sielaff, K; Snow, S; Verma, AK; Viner, JL, 2010) |
| "With the incidence of nonmelanoma skin cancer on the rise, current prevention methods, such as the use of sunscreens, have yet to prove adequate to reverse this trend." | 1.37 | New agents for prevention of ultraviolet-induced nonmelanoma skin cancer. ( Athar, M; Camp, WL; Elmets, CA; Turnham, JW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valejo Coelho, MM | 1 |
| Carvalho, R | 1 |
| Bailey, HH | 2 |
| Kim, K | 2 |
| Verma, AK | 1 |
| Sielaff, K | 1 |
| Larson, PO | 1 |
| Snow, S | 2 |
| Lenaghan, T | 1 |
| Viner, JL | 1 |
| Douglas, J | 1 |
| Dreckschmidt, NE | 1 |
| Hamielec, M | 1 |
| Pomplun, M | 1 |
| Sharata, HH | 1 |
| Puchalsky, D | 1 |
| Berg, ER | 1 |
| Havighurst, TC | 1 |
| Carbone, PP | 1 |
| Camp, WL | 1 |
| Turnham, JW | 1 |
| Athar, M | 2 |
| Elmets, CA | 1 |
| Prado, R | 1 |
| Francis, SO | 1 |
| Mason, MN | 1 |
| Wing, G | 1 |
| Gamble, RG | 1 |
| Dellavalle, R | 1 |
| Kreul, SM | 1 |
| Havighurst, T | 1 |
| Mendonça, EA | 1 |
| Wood, GS | 1 |
| Borich, A | 1 |
| Verma, A | 1 |
| Tang, X | 1 |
| Kim, AL | 1 |
| Feith, DJ | 1 |
| Pegg, AE | 1 |
| Russo, J | 1 |
| Zhang, H | 1 |
| Aszterbaum, M | 1 |
| Kopelovich, L | 1 |
| Epstein, EH | 1 |
| Bickers, DR | 1 |
1 review available for eflornithine and Carcinoma, Basal Cell, Pigmented
| Article | Year |
|---|---|
Nonmelanoma skin cancer chemoprevention.
Topics: Acitretin; Aminolevulinic Acid; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carc | 2011 |
2 trials available for eflornithine and Carcinoma, Basal Cell, Pigmented
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancer.
Topics: Antineoplastic Agents; Audiometry; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Double-Blind Met | 2010 |
A phase III skin cancer chemoprevention study of DFMO: long-term follow-up of skin cancer events and toxicity.
Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Double-Blind Method; Eflornithine; Fem | 2012 |
3 other studies available for eflornithine and Carcinoma, Basal Cell, Pigmented
| Article | Year |
|---|---|
Use of Eflornithine Hydrochloride Cream to Reduce Facial Hair Growth in Flapped Skin.
Topics: Aged; Carcinoma, Basal Cell; Dermoscopy; Eflornithine; Esthetics; Female; Forehead; Hair; Humans; Hy | 2019 |
New agents for prevention of ultraviolet-induced nonmelanoma skin cancer.
Topics: Anilides; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotenoids; Cell Transformation, Neoplas | 2011 |
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Eflornithine; Heterozygote; Intracellular | 2004 |