eflornithine has been researched along with Carcinoid Tumor in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Establishment of this human carcinoid xenograft line, BON, provides an excellent model to study further the biological behavior of carcinoid tumors and the in vivo effect of chemotherapeutic agents on tumor growth." | 1.28 | Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth. ( Allen, E; Evers, BM; Hurlbut, SC; Kim, SW; Rajaraman, S; Reubi, JC; Singh, P; Thompson, JC; Townsend, CM; Upp, JR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Litvak, DA | 1 |
| Papaconstantinou, HT | 1 |
| Ko, TC | 1 |
| Townsend, CM | 3 |
| Evers, BM | 2 |
| Hurlbut, SC | 2 |
| Tyring, SK | 1 |
| Uchida, T | 1 |
| Thompson, JC | 2 |
| Upp, JR | 1 |
| Allen, E | 1 |
| Kim, SW | 1 |
| Rajaraman, S | 1 |
| Singh, P | 1 |
| Reubi, JC | 1 |
3 other studies available for eflornithine and Carcinoid Tumor
| Article | Year |
|---|---|
A novel cytotoxic agent for human carcinoid tumors.
Topics: Antineoplastic Agents; Carcinoid Tumor; Cell Division; Drug Screening Assays, Antitumor; Eflornithin | 1998 |
Novel therapy for the treatment of human carcinoid.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoid Tumor; Cell Line; Di | 1991 |
Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth.
Topics: Animals; Binding Sites; Carcinoid Tumor; Cell Division; Cell Line; DNA; Eflornithine; Gastrins; Huma | 1991 |