eflornithine has been researched along with Brain Stem Neoplasms in 1 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Brain Stem Neoplasms: Benign and malignant intra-axial tumors of the MESENCEPHALON; PONS; or MEDULLA OBLONGATA of the BRAIN STEM. Primary and metastatic neoplasms may occur in this location. Clinical features include ATAXIA, cranial neuropathies (see CRANIAL NERVE DISEASES), NAUSEA, hemiparesis (see HEMIPLEGIA), and quadriparesis. Primary brain stem neoplasms are more frequent in children. Histologic subtypes include GLIOMA; HEMANGIOBLASTOMA; GANGLIOGLIOMA; and EPENDYMOMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, A | 1 |
| Gamble, LD | 1 |
| Upton, DH | 1 |
| Ung, C | 1 |
| Yu, DMT | 1 |
| Ehteda, A | 1 |
| Pandher, R | 1 |
| Mayoh, C | 1 |
| Hébert, S | 1 |
| Jabado, N | 1 |
| Kleinman, CL | 1 |
| Burns, MR | 1 |
| Norris, MD | 1 |
| Haber, M | 1 |
| Tsoli, M | 1 |
| Ziegler, DS | 1 |
1 other study available for eflornithine and Brain Stem Neoplasms
| Article | Year |
|---|---|
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.
Topics: Animals; Biological Transport; Brain Stem Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferatio | 2021 |