eflornithine has been researched along with Brain Neoplasms in 49 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although the efficacy of the nitrosourea-based combination chemotherapy procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, and vincristine (PCV) has been previously demonstrated in the setting of anaplastic/intermediate-grade gliomas, the benefit for glioblastoma patients remains unproven." | 9.09 | Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme. ( Bruner, JM; Chang, SM; Choucair, A; Flynn, PJ; Gleason, MJ; Hess, KR; Jaeckle, KA; Kyritsis, AP; Levin, VA; Prados, MD; Uhm, JH, 2000) |
| "This study compared the antitumor activity of oral eflornithine with that of oral eflornithine combined with intravenous mitoguazone in the treatment of patients with recurrent or progressive glioblastoma multiforme as well as nonglioblastoma anaplastic gliomas." | 9.07 | Treatment of recurrent gliomas with eflornithine. ( Gleason, MJ; Ictech, S; Levin, VA; Malec, M; Prados, MD; Yung, WK, 1992) |
| " For these reasons, the anti-glioblastoma drug temozolomide was tested in vitro for activity against bloodstream forms of T." | 7.85 | Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. ( Rushworth, SA; Steverding, D, 2017) |
| "In the current study, we sought to determine whether the addition of DFMO (alpha-difluoromethyl ornithine; eflornithine), an inhibitor of ornithine decarboxylase, to a nitrosourea-based therapy procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, vincristine (PCV) would be more effective as a postirradiation adjuvant therapy for anaplastic gliomas (AG) than PCV alone." | 5.10 | Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas. ( Bruner, JM; Choucair, A; Flynn, PJ; Gleason, MJ; Hess, KR; Ictech, S; Jaeckle, KA; Kim, HW; Kyritsis, AP; Levin, VA; Prados, MD; Yung, WK, 2003) |
| "Although the efficacy of the nitrosourea-based combination chemotherapy procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, and vincristine (PCV) has been previously demonstrated in the setting of anaplastic/intermediate-grade gliomas, the benefit for glioblastoma patients remains unproven." | 5.09 | Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme. ( Bruner, JM; Chang, SM; Choucair, A; Flynn, PJ; Gleason, MJ; Hess, KR; Jaeckle, KA; Kyritsis, AP; Levin, VA; Prados, MD; Uhm, JH, 2000) |
| "This study compared the antitumor activity of oral eflornithine with that of oral eflornithine combined with intravenous mitoguazone in the treatment of patients with recurrent or progressive glioblastoma multiforme as well as nonglioblastoma anaplastic gliomas." | 5.07 | Treatment of recurrent gliomas with eflornithine. ( Gleason, MJ; Ictech, S; Levin, VA; Malec, M; Prados, MD; Yung, WK, 1992) |
| " For these reasons, the anti-glioblastoma drug temozolomide was tested in vitro for activity against bloodstream forms of T." | 3.85 | Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. ( Rushworth, SA; Steverding, D, 2017) |
| "889 with respect to OS, while BEV in combination with TMZ - with a probability of 0." | 2.53 | A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT). ( Ding, L; Gao, L; Lv, P; Qi, L; Wang, S; Wang, W; Xu, Y; Zhao, D; Zhong, Y, 2016) |
| "We have determined the pharmacokinetic parameters for diffusion of alpha-[5-14C]-difluoromethylornithine (DFMO) from blood to brain, blood to cerebrospinal fluid (CSF), 9L rat brain tumor to adjacent brain, and blood to the subcutaneously-implanted 9L tumor in rats, and within the CSF of beagle dogs." | 1.27 | Brain, CSF, and tumor pharmacokinetics of alpha-difluoromethylornithine in rats and dogs. ( Byrd, DJ; Csejtey, J; Levin, VA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (53.06) | 18.7374 |
| 1990's | 12 (24.49) | 18.2507 |
| 2000's | 6 (12.24) | 29.6817 |
| 2010's | 5 (10.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steverding, D | 1 |
| Rushworth, SA | 1 |
| Levin, VA | 12 |
| Ictech, SE | 1 |
| Hess, KR | 4 |
| Lozier, AM | 1 |
| Rich, ME | 1 |
| Grawe, AP | 1 |
| Peck, AS | 1 |
| Zhao, P | 1 |
| Chang, AT | 1 |
| Bond, JP | 1 |
| Sholler, GS | 1 |
| Alexiou, GA | 1 |
| Tsamis, KI | 1 |
| Vartholomatos, E | 1 |
| Peponi, E | 1 |
| Tzima, E | 1 |
| Tasiou, I | 1 |
| Lykoudis, E | 1 |
| Tsekeris, P | 1 |
| Kyritsis, AP | 4 |
| Qi, L | 1 |
| Ding, L | 1 |
| Wang, S | 2 |
| Zhong, Y | 1 |
| Zhao, D | 1 |
| Gao, L | 1 |
| Wang, W | 1 |
| Lv, P | 1 |
| Xu, Y | 1 |
| Choucair, A | 2 |
| Flynn, PJ | 2 |
| Jaeckle, KA | 3 |
| Yung, WK | 3 |
| Prados, MD | 6 |
| Bruner, JM | 2 |
| Ictech, S | 2 |
| Gleason, MJ | 3 |
| Kim, HW | 1 |
| Jochec, JL | 1 |
| Shantz, LM | 1 |
| Koch, PE | 1 |
| Pegg, AE | 3 |
| Wahlfors, T | 1 |
| Hakkarainen, T | 1 |
| Jänne, J | 1 |
| Alhonen, L | 1 |
| Wahlfors, J | 1 |
| Bjerkvig, R | 1 |
| Oredsson, SM | 7 |
| Marton, LJ | 24 |
| Linden, M | 1 |
| Deen, DF | 18 |
| Gray, JW | 2 |
| Tofilon, PJ | 1 |
| Feuerstein, BG | 4 |
| Rosenblum, ML | 1 |
| Csejtey, J | 1 |
| Byrd, DJ | 1 |
| Hung, DT | 3 |
| Shafer, RH | 1 |
| Alhonen-Hongisto, L | 5 |
| Sano, Y | 1 |
| Wilson, CB | 3 |
| Gutin, PH | 3 |
| Seidenfeld, J | 3 |
| Hervatin, SJ | 1 |
| Koch-Weser, J | 1 |
| McCann, PP | 1 |
| Sjoerdsma, A | 1 |
| Kurihara, H | 2 |
| Matsuzaki, S | 2 |
| Tamura, M | 2 |
| Sugimoto, H | 1 |
| Tsukahara, T | 2 |
| Yamazaki, H | 2 |
| Chiarodo, A | 1 |
| Grimm, EA | 1 |
| Fike, JR | 1 |
| Israel, MA | 1 |
| Kun, LE | 1 |
| Packer, RJ | 1 |
| Redgate, ES | 4 |
| Grudziak, A | 1 |
| Floyd, KL | 1 |
| Deutsch, M | 3 |
| Boggs, SS | 4 |
| Grudziak, AG | 2 |
| Uhm, JH | 1 |
| Chang, SM | 2 |
| Wara, WM | 1 |
| Sneed, PK | 1 |
| McDermott, M | 1 |
| Rabbitt, J | 1 |
| Page, M | 1 |
| Malec, M | 2 |
| Davis, RL | 2 |
| Lamborn, K | 1 |
| Phillips, TL | 1 |
| Larson, DA | 1 |
| Wong, ET | 1 |
| Alexander, D | 1 |
| Magra, TR | 1 |
| Henretty, JS | 1 |
| Patrene, KD | 1 |
| Melino, G | 1 |
| Stephanou, A | 1 |
| Annicchiarico-Petruzzelli, M | 1 |
| Finazzi-Agró, A | 1 |
| Knight, RA | 1 |
| Lightman, SL | 1 |
| Szöllösi, J | 2 |
| Basu, HS | 2 |
| Sturkenboom, MC | 1 |
| Delcros, JG | 1 |
| Csokan, PP | 1 |
| Hunter, KJ | 2 |
| Pellarin, M | 1 |
| Milam, KM | 1 |
| Prados, M | 1 |
| Rodriguez, L | 1 |
| Chamberlain, M | 1 |
| Silver, P | 2 |
| Levin, V | 1 |
| Cohen, AR | 1 |
| Pietronigro, DD | 1 |
| Cravioto, H | 1 |
| Flamm, ES | 1 |
| Chamberlain, MC | 1 |
| Choucair, AK | 1 |
| Berger, MS | 1 |
| Seager, M | 1 |
3 reviews available for eflornithine and Brain Neoplasms
| Article | Year |
|---|---|
Clinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Eflornithine; Glioma; Hum | 2018 |
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasm | 2016 |
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Efl | 1985 |
5 trials available for eflornithine and Brain Neoplasms
| Article | Year |
|---|---|
Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasm | 2003 |
Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; | 2000 |
Phase III trial of accelerated hyperfractionation with or without difluromethylornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Disease-Free Surviva | 2001 |
Response and progression in recurrent malignant glioma.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Alitretinoin; Antineoplastic Combine | 1999 |
Treatment of recurrent gliomas with eflornithine.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Eflornithine; Female; Glioblastom | 1992 |
41 other studies available for eflornithine and Brain Neoplasms
| Article | Year |
|---|---|
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Eflornit | 2017 |
Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Disease P | 2015 |
Combination treatment of TRAIL, DFMO and radiation for malignant glioma cells.
Topics: Apoptosis; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Com | 2015 |
Tissue-based assay for ornithine decarboxylase to identify patients likely to respond to difluoromethylornithine.
Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Eflornithine; Humans; Immunohistochemi | 2004 |
In vivo enhancement of herpes simplex virus thymidine kinase/ganciclovir cancer gene therapy with polyamine biosynthesis inhibition.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Eflornithine; Female; Ganciclovir; Genes, Transgeni | 2006 |
Cell cycle age response of 9L cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and modification by alpha-difluoromethylornithine.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Eflornithine; Ki | 1983 |
Decreased cytotoxicity of 1-beta-D-arabinofuranosylcytosine in 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine in vitro.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; DNA; Drug Synergis | 1983 |
Differential potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine in chloroethylnitrosourea-sensitive and -resistant 9L rat brain tumor cells in vitro.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Drug Resistance; Drug Synerg | 1983 |
Brain, CSF, and tumor pharmacokinetics of alpha-difluoromethylornithine in rats and dogs.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Cerebrospinal Fluid; Dogs; Eflornithine; Kin | 1983 |
Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Eflornithine; Molecular Conformation; Ornithine; Polyamines | 1983 |
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Surviva | 1983 |
Decreased cytotoxicity of aziridinylbenzoquinone caused by polyamine depletion in 9L rat brain tumor cells in vitro.
Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Cell Line; Cel | 1984 |
Effects of alpha-difluoromethylornithine on the growth of 9L rat brain tumor multicellular spheroids and their response to 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Drug Ther | 1984 |
Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Drug Synergism; Eflornithine; Kinetics; Ornithine; | 1984 |
Possible factors in the potentiation of 1-(2-chloroethyl)-3-trans-4-methylcyclohexyl-1-nitrosourea cytotoxicity by alpha-difluoromethylornithine in 9L rat brain tumor cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line; Cell Survival; | 1984 |
Decreased cell kill of vincristine and methotrexate against 9L rat brain tumor cells in vitro caused by alpha-difluoromethylornithine-induced polyamine depletion.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Eflornithi | 1984 |
New therapeutic approaches for brain tumors.
Topics: Brachytherapy; Brain Neoplasms; Bromodeoxyuridine; Eflornithine; Humans; Hyperthermia, Induced; Iodi | 1984 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithin | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; | 1981 |
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationsh | 1981 |
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Topics: Animals; Brain Neoplasms; Carmustine; Drug Administration Schedule; Drug Synergism; Drug Therapy, Co | 1981 |
Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cisplatin; DNA; Eflornithine; Neoplasms, Experimental; Orn | 1982 |
An approach to the use of polyamine inhibitors for cancer therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Ef | 1981 |
alpha-Difluoromethylornithine increases the anti-tumor effect of cis-diamminedichloroplatinum in G-XII rat glioma.
Topics: Acetyltransferases; Animals; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Movement; Cells, Cultur | 1995 |
Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy. Organ System Program, National Cancer Institute.
Topics: Adult; Animals; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as | 1993 |
Effect of D,L-alpha-difluoromethylornithine (DFMO) enhanced [3H]putrescine uptake on 9L tumor cell growth and colony forming efficiency.
Topics: Animals; Biological Transport; Brain Neoplasms; Cell Division; Eflornithine; Glioma; Kinetics; Putre | 1993 |
Difluoromethylornithine enhanced uptake of tritiated putrescine in 9L rat brain tumors.
Topics: Animals; Brain; Brain Neoplasms; Eflornithine; Glioma; Male; Ornithine Decarboxylase Inhibitors; Put | 1997 |
Enhanced uptake of [3H] spermidine by 9L rat brain tumors after direct intratumoral infusion of inhibitors of enzymes of the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Body Weight; Brain Neoplasms; Corpu | 1999 |
The effect of DFMO induced uptake of [3H] putrescine on human glioma cells.
Topics: Biological Transport; Brain Neoplasms; Cell Adhesion; Cell Division; Colony-Forming Units Assay; Efl | 2001 |
IGF-II mRNA expression in LI human glioblastoma cell line parallels cell growth.
Topics: Blotting, Northern; Brain Neoplasms; Eflornithine; Glioma; Growth Hormone-Releasing Hormone; Humans; | 1992 |
alpha-Difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture.
Topics: Biogenic Polyamines; Brain Neoplasms; Calcium; Eflornithine; Humans; Ion Channel Gating; Platelet-De | 1992 |
The additive effect of alpha-difluoromethylornithine (DFMO) and radiation therapy on a rat glioma model.
Topics: Animals; Biogenic Polyamines; Brain Neoplasms; Combined Modality Therapy; Disease Models, Animal; Ef | 1992 |
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Topics: Brain Neoplasms; Cell Nucleus; Chromatin; Culture Media, Serum-Free; Deoxyribonuclease I; Eflornithi | 1992 |
Effect of alpha-difluoromethylornithine on 1,3-bis(2-chloroethyl)-1-nitrosourea and cis-diamminedichloroplatinum(II) cytotoxicity, DNA interstrand cross-linking, and growth in human brain tumor cell lines in vitro.
Topics: Biogenic Polyamines; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Eflornit | 1990 |
Differential response to 1,3-bis (2-chloroethyl)-1-nitrosourea in drug-resistant and -sensitive 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine and 6-thioguanine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Dru | 1989 |
Cell proliferation and polyamine metabolism in 9L cells treated with (2R,5R)-6-heptyne-2,5-diamine or alpha-difluoromethylornithine.
Topics: Alkynes; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Division; Diamines; Eflor | 1989 |
Treatment of recurrent gliomas with 1,3-bis(2-chloroethyl)-1-nitrosourea and alpha-difluoromethylornithine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Combined M | 1989 |
Effect of difluoromethylornithine on the antiglioma therapeutic efficacy of intra-arterial BCNU.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Eflornithine; | 1986 |
Phase I-II study of eflornithine and mitoguazone combined in the treatment of recurrent primary brain tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Drug Eval | 1987 |
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mito | 1985 |
Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Survival; Cyclohexylamines; Eflornithine; Mit | 1985 |