eflornithine has been researched along with Black Fever in 4 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, S | 1 |
| Mukherjee, A | 1 |
| Khomutov, AR | 1 |
| Persson, L | 1 |
| Heby, O | 1 |
| Chatterjee, M | 1 |
| Madhubala, R | 2 |
| Olenyik, T | 1 |
| Gilroy, C | 1 |
| Ullman, B | 1 |
| Mukhopadhyay, R | 1 |
| Gradoni, L | 1 |
| Iorio, MA | 1 |
| Gramiccia, M | 1 |
| Orsini, S | 1 |
4 other studies available for eflornithine and Black Fever
| Article | Year |
|---|---|
Antileishmanial effect of 3-aminooxy-1-aminopropane is due to polyamine depletion.
Topics: Animals; Drug Resistance; Leishmania donovani; Leishmaniasis, Visceral; Ornithine Decarboxylase; Orn | 2007 |
Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice.
Topics: Administration, Oral; Animals; Disease Models, Animal; Eflornithine; Enzyme Inhibitors; Female; Leis | 2011 |
Effect of a bis(benzyl)polyamine analogue, and DL-alpha-difluoromethylornithine on parasite suppression and cellular polyamine levels in golden hamster during Leishmania donovani infection.
Topics: Animals; Antimony Sodium Gluconate; Biogenic Polyamines; Cricetinae; Eflornithine; Leishmania donova | 1993 |
In vivo effect of eflornithine (DFMO) and some related compounds on Leishmania infantum preliminary communication.
Topics: Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Eflornithine; Leishmania d | 1989 |