Page last updated: 2024-10-25

eflornithine and Astrocytosis

eflornithine has been researched along with Astrocytosis in 2 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"DFMO markedly suppressed hippocampal gliosis as measured by GFAP immunoblotting seven days postsurgery."1.29Difluoromethylornithine counteracts lesion-induced astrogliosis in rat hippocampus: enhancement of inhibitory effect by combined treatment with GM1 ganglioside. ( Jegliński, W; Oderfeld-Nowak, B; Skup, M; Zaremba, M, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jegliński, W1
Skup, M1
Zaremba, M1
Oderfeld-Nowak, B1
O'Callaghan, JP1
Seidler, FJ1

Other Studies

2 other studies available for eflornithine and Astrocytosis

ArticleYear
Difluoromethylornithine counteracts lesion-induced astrogliosis in rat hippocampus: enhancement of inhibitory effect by combined treatment with GM1 ganglioside.
    Acta neurobiologiae experimentalis, 1996, Volume: 56, Issue:2

    Topics: Animals; Astrocytes; Biomarkers; Eflornithine; G(M1) Ganglioside; Glial Fibrillary Acidic Protein; G

1996
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced astrogliosis does not require activation of ornithine decarboxylase.
    Neuroscience letters, 1992, Dec-14, Volume: 148, Issue:1-2

    Topics: Animals; Astrocytes; Corpus Striatum; Eflornithine; Enzyme Activation; Female; Glial Fibrillary Acid

1992