eflornithine has been researched along with Angiogenesis, Pathologic in 5 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DFMO inhibited the proliferation of B16 melanoma cells in culture but the inhibitory effect was much less than that on BPAE cells." | 1.28 | Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro. ( Enomoto, M; Kinoshita, A; Nishida, Y; Pan, HO; Suzuki, F; Takigawa, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konturek, SJ | 1 |
| Brzozowski, T | 1 |
| Majka, I | 1 |
| Pawlik, W | 1 |
| Stachura, J | 1 |
| Jasnis, MA | 1 |
| Klein, S | 1 |
| Monte, M | 1 |
| Davel, L | 1 |
| Sacerdote de Lustig, E | 1 |
| Algranati, ID | 1 |
| Takahashi, Y | 1 |
| Mai, M | 1 |
| Nishioka, K | 1 |
| Lan, L | 1 |
| Trempus, C | 1 |
| Gilmour, SK | 1 |
| Takigawa, M | 1 |
| Enomoto, M | 1 |
| Nishida, Y | 1 |
| Pan, HO | 1 |
| Kinoshita, A | 1 |
| Suzuki, F | 1 |
5 other studies available for eflornithine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Omentum and basic fibroblast growth factor in healing of chronic gastric ulcerations in rats.
Topics: Animals; Blood Flow Velocity; Chronic Disease; Dinoprostone; Eflornithine; Fibroblast Growth Factor | 1994 |
Polyamines prevent DFMO-mediated inhibition of angiogenesis.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Eflornithine; Female; Lymphocytes; Mammary Neoplasms, | 1994 |
alpha-difluoromethylornithine induces apoptosis as well as anti-angiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Disease Models, Animal; Eflornithine; Endo | 2000 |
Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Crosses, Genetic; Eflornithine; | 2000 |
Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro.
Topics: Animals; Cattle; Cell Division; Chick Embryo; DNA, Neoplasm; Eflornithine; Endothelium, Vascular; Me | 1990 |