Page last updated: 2024-10-25

eflornithine and Aging

eflornithine has been researched along with Aging in 8 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Imipramine (IMI) was administered s."1.27Effect of prenatal imipramine exposure on development of the postnatal rat heart and brain. ( Delongchamp, RR; Harmon, JR; Kimmel, GL; Webb, PJ, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Withrow, C1
Ashraf, S1
O'Leary, T1
Johnson, LR1
Fitzgerald, ME1
Johnson, DA1
Rorke, EA1
Katzenellenbogen, BS1
Gritli-Linde, A1
Linde, A1
Buts, JP1
De Keyser, N1
Romain, N1
Dandrifosse, G1
Sokal, E1
Nsengiyumva, T1
Gray, JA1
Kavlock, RJ1
Bell, JM1
Whitmore, WL1
Slotkin, TA1
Harmon, JR1
Webb, PJ1
Kimmel, GL1
Delongchamp, RR1
Rui, H1
Purvis, K1

Other Studies

8 other studies available for eflornithine and Aging

ArticleYear
Effect of polyamine depletion on cone photoreceptors of the developing rabbit retina.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:9

    Topics: Aging; Animals; Animals, Newborn; Biogenic Polyamines; Calbindins; Cell Culture Techniques; Chromato

2002
Dissociated regulation of growth and ornithine decarboxylase activity by estrogen in the rat uterus.
    Biochemical and biophysical research communications, 1984, Aug-16, Volume: 122, Issue:3

    Topics: Aging; Animals; Castration; Eflornithine; Estradiol; Female; Organ Size; Ornithine; Ornithine Decarb

1984
Localization of ornithine decarboxylase in mouse teeth. An in vitro and in vivo study.
    The International journal of developmental biology, 1994, Volume: 38, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cycloheximide; Eflornithine; Female; Kidney Tubul

1994
Response of rat immature enterocytes to insulin: regulation by receptor binding and endoluminal polyamine uptake.
    Gastroenterology, 1994, Volume: 106, Issue:1

    Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Antibodies, Monoclonal; Eflornithine; Hydrolases; I

1994
Physiological consequences of early neonatal growth retardation: effects of alpha-difluoromethylornithine on renal growth and function in the rat.
    Teratology, 1991, Volume: 43, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Creatinine; Eflornithine; Femal

1991
Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivity.
    Neuroscience, 1986, Volume: 17, Issue:2

    Topics: Aging; Animals; Body Weight; Brain; DNA; Eflornithine; Female; Injections, Subcutaneous; Nerve Tissu

1986
Effect of prenatal imipramine exposure on development of the postnatal rat heart and brain.
    Teratogenesis, carcinogenesis, and mutagenesis, 1986, Volume: 6, Issue:3

    Topics: Aging; Animals; Body Weight; Brain; Dihydroalprenolol; Eflornithine; Female; Heart; Imipramine; Litt

1986
Independent control of citrate production and ornithine decarboxylase by prolactin in the lateral lobe of the rat prostate.
    Molecular and cellular endocrinology, 1987, Volume: 52, Issue:1-2

    Topics: Aging; Animals; Citrates; Eflornithine; Hypophysectomy; Kinetics; Male; Ornithine Decarboxylase; Pro

1987