eflornithine has been researched along with Adverse Drug Event in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Safety was further assessed based on treatment emergent adverse events (AEs) occurring during hospitalisation." | 2.77 | In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness. ( Blesson, S; Blum, J; Ghabri, S; Ilunga, M; Kande, V; Kisala, M; Kuemmerle, A; Lumpungu, I; Mordt, OV; Mubwa, N; Mutanda, S; Mutombo, W; Nganzobo, P; Schmid, C; Tete, D, 2012) |
| "Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female." | 2.61 | Hirsutism in Women. ( Bain, J; Matheson, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Matheson, E | 1 |
| Bain, J | 1 |
| Schmid, C | 1 |
| Kuemmerle, A | 1 |
| Blum, J | 1 |
| Ghabri, S | 1 |
| Kande, V | 1 |
| Mutombo, W | 1 |
| Ilunga, M | 1 |
| Lumpungu, I | 1 |
| Mutanda, S | 1 |
| Nganzobo, P | 1 |
| Tete, D | 1 |
| Mubwa, N | 1 |
| Kisala, M | 1 |
| Blesson, S | 1 |
| Mordt, OV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study to Assess the Clinical Tolerability, Feasibility and Effectiveness Under Field Conditions of the Combination of Nifurtimox and Eflornithine (NECT) for the Treatment of T.b.Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encepha[NCT00906880] | Phase 4 | 630 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for eflornithine and Adverse Drug Event
| Article | Year |
|---|---|
Hirsutism in Women.
Topics: Adrenal Hyperplasia, Congenital; Androgen Antagonists; Antineoplastic Agents, Hormonal; Contraceptiv | 2019 |
1 trial available for eflornithine and Adverse Drug Event
| Article | Year |
|---|---|
In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness.
Topics: Adolescent; Adult; Child; Child, Preschool; Democratic Republic of the Congo; Drug Therapy, Combinat | 2012 |
1 other study available for eflornithine and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |