eflornithine has been researched along with Acute Confusional Senile Dementia in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathogenesis of Alzheimer's disease (AD) is a critical unsolved question; and although recent studies have demonstrated a strong association between altered brain immune responses and disease progression, the mechanistic cause of neuronal dysfunction and death is unknown." | 1.42 | Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. ( Brown, CM; Colton, CA; Everhart, AL; Gunn, MD; Hoofnagle, AN; Jansen, M; Kan, MJ; Lee, JE; Vitek, MP; Wilson, JG, 2015) |
| "Spermine has been reported to function directly as a free radical scavenger." | 1.31 | Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity. ( Ain, KB; Butterfield, DA; Varadarajan, S; Yatin, M; Yatin, SM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kan, MJ | 1 |
| Lee, JE | 1 |
| Wilson, JG | 1 |
| Everhart, AL | 1 |
| Brown, CM | 1 |
| Hoofnagle, AN | 1 |
| Jansen, M | 1 |
| Vitek, MP | 1 |
| Gunn, MD | 1 |
| Colton, CA | 1 |
| Yatin, SM | 1 |
| Yatin, M | 1 |
| Varadarajan, S | 1 |
| Ain, KB | 1 |
| Butterfield, DA | 1 |
2 other studies available for eflornithine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Arginine; Bra | 2015 |
Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity.
Topics: Adenosine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Eflornithi | 2001 |