eflornithine has been researched along with Acute Brain Injuries in 7 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosi, S | 1 |
| Ferguson, R | 1 |
| Fishman, K | 1 |
| Allen, A | 1 |
| Raber, J | 1 |
| Fike, JR | 1 |
| Dienel, GA | 1 |
| Cruz, NF | 1 |
| Trout, JJ | 1 |
| Lu, CY | 2 |
| Goldstone, AD | 2 |
| Sahgal, S | 1 |
| Başkaya, MK | 1 |
| Rao, AM | 1 |
| Puckett, L | 1 |
| Prasad, MR | 1 |
| Dempsey, RJ | 1 |
| Johnson, TD | 1 |
| Zini, I | 1 |
| Zoli, M | 1 |
| Grimaldi, R | 1 |
| Pich, EM | 1 |
| Biagini, G | 1 |
| Fuxe, K | 1 |
| Agnati, LF | 1 |
| Koenig, H | 1 |
1 review available for eflornithine and Acute Brain Injuries
| Article | Year |
|---|---|
Polyamines and cerebral ischemia.
Topics: Adenosylmethionine Decarboxylase; Animals; Barbiturates; Biogenic Polyamines; Brain Injuries; Brain | 1998 |
6 other studies available for eflornithine and Acute Brain Injuries
| Article | Year |
|---|---|
The polyamine inhibitor alpha-difluoromethylornithine modulates hippocampus-dependent function after single and combined injuries.
Topics: Animals; Brain Injuries; Cognition; Cognition Disorders; Eflornithine; Enzyme Inhibitors; Hippocampu | 2012 |
Induction of brain ornithine decarboxylase during recovery from metabolic, mechanical, thermal, or chemical injury.
Topics: Animals; Brain; Brain Injuries; Dactinomycin; Eflornithine; Hot Temperature; Hypoxia; Injections, In | 1984 |
Polyamines and NMDA receptors modulate pericapillary astrocyte swelling following cerebral cryo-injury in the rat.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain; Brain Injuries; Capillaries; Cold Temperature; Dizo | 1995 |
Effect of difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury.
Topics: Animals; Brain Injuries; Disease Models, Animal; Edema; Eflornithine; Male; Ornithine Decarboxylase; | 1996 |
Evidence for a role of neosynthetized putrescine in the increase of glial fibrillary acidic protein immunoreactivity induced by a mechanical lesion in the rat brain.
Topics: Animals; Astrocytes; Brain Injuries; Corpus Striatum; Eflornithine; Glial Fibrillary Acidic Protein; | 1990 |
Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin.
Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Brain Injuries; Cold Temperature; Cycloheximide; Dacti | 1989 |