efinaconazole has been researched along with Mycoses* in 2 studies
2 other study(ies) available for efinaconazole and Mycoses
Article | Year |
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Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
Due to the increased morbidity and mortality by fungal infections and the emergence of severe antifungal resistance, there is an urgent need for new antifungal agents. Here, we screened for antifungal activity in our in-house library through the minimum inhibitory concentration test and derived two hit compounds with moderate antifungal activities. The hit compounds' antifungal activities and drug-like properties were optimized by substituting various aryl ring, alkyl chain, and methyl groups. Among the optimized compounds, Topics: Animals; Antifungal Agents; Cell Wall; Drug Evaluation, Preclinical; Drug Synergism; Female; Fungi; Humans; Male; Mice; Microbial Sensitivity Tests; Mycoses; Rats, Sprague-Dawley | 2021 |
The Topics: Adult; Antifungal Agents; Ascomycota; Child, Preschool; Drug Resistance, Fungal; Female; Humans; Imidazoles; Male; Microbial Sensitivity Tests; Middle Aged; Mycoses; Triazoles; Yeasts; Young Adult | 2017 |