efinaconazole and Mycoses

efinaconazole has been researched along with Mycoses* in 2 studies

Other Studies

2 other study(ies) available for efinaconazole and Mycoses

ArticleYear
Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
    Journal of medicinal chemistry, 2021, 11-11, Volume: 64, Issue:21

    Due to the increased morbidity and mortality by fungal infections and the emergence of severe antifungal resistance, there is an urgent need for new antifungal agents. Here, we screened for antifungal activity in our in-house library through the minimum inhibitory concentration test and derived two hit compounds with moderate antifungal activities. The hit compounds' antifungal activities and drug-like properties were optimized by substituting various aryl ring, alkyl chain, and methyl groups. Among the optimized compounds,

    Topics: Animals; Antifungal Agents; Cell Wall; Drug Evaluation, Preclinical; Drug Synergism; Female; Fungi; Humans; Male; Mice; Microbial Sensitivity Tests; Mycoses; Rats, Sprague-Dawley

2021
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:11

    The

    Topics: Adult; Antifungal Agents; Ascomycota; Child, Preschool; Drug Resistance, Fungal; Female; Humans; Imidazoles; Male; Microbial Sensitivity Tests; Middle Aged; Mycoses; Triazoles; Yeasts; Young Adult

2017