Page last updated: 2024-09-03

efegatran and Thrombosis

efegatran has been researched along with Thrombosis in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey, DL; Bastian, JA; Briggs, SL; Chirgadze, NY; Clawson, DK; Denney, ML; Gifford-Moore, DS; Harper, RW; Johnson, LM; Klimkowski, VJ; Kohn, TJ; Lin, HS; McCowan, JR; Richett, ME; Sall, DJ; Smith, AJ; Smith, GF; Snyder, DW; Takeuchi, K; Utterback, BG; Yan, SC; Zhang, M1
Das, J; Kimball, SD; Lau, WF; Ogletree, ML; Reid, JA; Roberts, DG; Schumacher, WA; Seiler, SM; Wang, TC1
Chang, CY; Chong, S; Das, J; Hall, SE; Han, WC; Iwanowicz, E; Kimball, SD; Lin, J; Malley, MF; Moquin, RV; Ogletree, ML; Reid, JA; Roberts, DG; Sack, JS; Schumacher, WA; Seiler, SM; Wang-Iverson, DB1
Bacher, P; Bajusz, S; Breddin, K; Fareed, J; Iqbal, O; Walenga, JM1
Lucchesi, BR; Sudo, Y1
Bagdy, D; Bajusz, S; Barabás, E; Szabó, G1

Other Studies

6 other study(ies) available for efegatran and Thrombosis

ArticleYear
Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of in vivo efficacy.
    Bioorganic & medicinal chemistry letters, 1999, Mar-08, Volume: 9, Issue:5

    Topics: Animals; Anticoagulants; Binding Sites; Crystallography, X-Ray; Disease Models, Animal; Humans; Models, Molecular; Rats; Structure-Activity Relationship; Thiophenes; Thrombin; Thrombosis

1999
Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues.
    Bioorganic & medicinal chemistry letters, 2002, Jan-07, Volume: 12, Issue:1

    Topics: Animals; Binding Sites; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Fibrinolytic Agents; Humans; Mice; Nipecotic Acids; Rats; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Substrate Specificity; Thrombin; Thrombosis

2002
Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
    Bioorganic & medicinal chemistry letters, 2002, Jan-07, Volume: 12, Issue:1

    Topics: Administration, Oral; Animals; Binding Sites; Crystallography, X-Ray; Dipeptides; Disease Models, Animal; Dogs; Drug Design; Drug Evaluation, Preclinical; Fibrinolytic Agents; Humans; Inhibitory Concentration 50; Macaca fascicularis; Mice; Serine Proteinase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thrombin; Thrombosis

2002
The antithrombotic and anticoagulant effects of a synthetic tripeptide and recombinant hirudin in various animal models.
    Thrombosis research, 1993, Aug-15, Volume: 71, Issue:4

    Topics: Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hirudin Therapy; Hirudins; Jugular Veins; Molecular Sequence Data; Oligopeptides; Rabbits; Recombinant Proteins; Thrombosis

1993
Antithrombotic effect of GYKI-14766 in a canine model of arterial and venous rethrombosis: a comparison with heparin.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:4

    Topics: Animals; Anistreplase; Antithrombins; Bleeding Time; Blood Circulation; Blood Flow Velocity; Carotid Arteries; Dogs; Heparin; Jugular Veins; Male; Oligopeptides; Partial Thromboplastin Time; Thrombolytic Therapy; Thrombosis

1996
Inhibition by D-MePhe-Pro-Arg-H (GYKI-14766) of thrombus growth in experimental models of thrombosis.
    Thrombosis and haemostasis, 1992, Aug-03, Volume: 68, Issue:2

    Topics: Amino Acid Sequence; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Disease Models, Animal; Male; Molecular Sequence Data; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Thrombophlebitis; Thrombosis

1992