efavirenz and Liver Dysfunction

efavirenz has been researched along with Liver Dysfunction in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's11 (91.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Branco, T; Caixas, U; Germano, I; Lampreia, F; Monteiro, EC; Papoila, AL; Pereira, SA1
Pulido, F; Torralba, M1
Boyd, MA; Cooper, DA; Dore, GJ; Duncombe, CJ; Lange, JM; Law, WP; Mahanontharit, A; Phanuphak, P; Ruxrungtham, K1
Amador, C; Benito, C; Ena, J; Fenoll, V; Pasquau, F1
Calza, L; Chiodo, F; Manfredi, R1
Antela, A; Aranzabal, L; Casado, JL; Diz, S; Dronda, F; Hernandez-Ranz, F; MarĂ­n, A; Moreno, A; Moreno, L; Moreno, S; Moya, J; Perez-Elias, MJ; Quereda, C1
Donahue, JP; Erdem, H; George, AL; Haas, DW; Haines, JL; Kim, RB; Motsinger, AA; Raffanti, S; Rebeiro, P; Ritchie, MD; Sterling, TR1
Aweeka, FT; Charlebois, E; Coates, C; Dorsey, G; German, P; Greenhouse, B; Havlir, D; Lindegardh, N; Rosenthal, PJ1
Cecelia, AJ; Devaleenal, B; Flanigan, T; Kumarasamy, N; Mayer, KH; Muthu, S; Palanivel, V; Venkatesh, KK; Yepthomi, T1
Frank, A; Katsounas, A; Klinker, H; Langmann, P1
Lo Caputo, S; Maserati, R; Pan, A; Regazzi, MB; Seminari, E; Villani, P1
Chaisson, RE; Mehta, SH; Moore, RD; Sulkowski, MS; Thomas, DL1

Reviews

1 review(s) available for efavirenz and Liver Dysfunction

ArticleYear
NNRTI hepatotoxicity: efavirenz versus nevirapine.
    Journal of HIV therapy, 2002, Volume: 7 Suppl 2

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Hepatitis B; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Liver Diseases; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors

2002

Trials

3 trial(s) available for efavirenz and Liver Dysfunction

ArticleYear
Efavirenz versus nevirapine in current clinical practice: a prospective, open-label observational study.
    Journal of acquired immune deficiency syndromes (1999), 2004, Apr-15, Volume: 35, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Central Nervous System Diseases; Cyclopropanes; Female; Follow-Up Studies; Gynecomastia; HIV Infections; Humans; Hypersensitivity; Liver Diseases; Male; Metabolic Diseases; Nevirapine; Oxazines; Pancreatic Diseases; Prospective Studies; Reverse Transcriptase Inhibitors; Viral Load

2004
Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting.
    Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Costs and Cost Analysis; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Liver; Liver Diseases; Male; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome

2007
Efavirenz-therapy in HIV-patients with underlying liver disease: importance of continuous TDM of EFV.
    European journal of medical research, 2007, Aug-16, Volume: 12, Issue:8

    Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Aspartate Aminotransferases; Benzoxazines; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Chromatography, High Pressure Liquid; Chronic Disease; Cyclopropanes; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; HIV Infections; Humans; Liver Diseases; Male; RNA, Viral; Viral Load

2007

Other Studies

8 other study(ies) available for efavirenz and Liver Dysfunction

ArticleYear
Efavirenz concentrations in HIV-infected patients with and without viral hepatitis.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Benzoxazines; Case-Control Studies; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Female; Follow-Up Studies; Hepatitis B, Chronic; Hepatitis C, Chronic; HIV Infections; Humans; Liver Diseases; Male; Pilot Projects; Reverse Transcriptase Inhibitors; Severity of Illness Index; Treatment Outcome; Viral Load

2008
Risk of severe hepatotoxicity associated with antiretroviral therapy in the HIV-NAT Cohort, Thailand, 1996-2001.
    AIDS (London, England), 2003, Oct-17, Volume: 17, Issue:15

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Incidence; Liver; Liver Diseases; Male; Nevirapine; Oxazines; Prevalence; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Thailand

2003
Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patients.
    International journal of STD & AIDS, 2003, Volume: 14, Issue:11

    Topics: Adult; Alanine Transaminase; Alcoholism; Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis C Antibodies; Hepatitis C, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Liver Diseases; Male; Multivariate Analysis; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Risk; Risk Factors; Transaminases

2003
Influence of liver fibrosis on highly active antiretroviral therapy-associated hepatotoxicity in patients with HIV and hepatitis C virus coinfection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Severity of Illness Index

2005
Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Sep-15, Volume: 43, Issue:6

    Topics: Adult; Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Genes, MDR; Genetic Variation; Genotype; HIV Infections; HIV-1; Humans; Liver; Liver Diseases; Male; Nevirapine; Oxazines; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors

2006
Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Mar-15, Volume: 44, Issue:6

    Topics: Adult; Alkynes; Amodiaquine; Artemisinins; Artesunate; Benzoxazines; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Oxazines; Reference Values; Risk Assessment; Sesquiterpenes; Transaminases

2007
High plasma levels of nelfinavir and efavirenz in two HIV-positive patients with hepatic disease.
    AIDS (London, England), 1999, May-07, Volume: 13, Issue:7

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Liver Diseases; Male; Nelfinavir; Oxazines; Reverse Transcriptase Inhibitors; Stavudine

1999
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Benzoxazines; Bilirubin; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Liver Diseases; Male; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome

2002