efavirenz and Encephalopathy, Toxic

efavirenz has been researched along with Encephalopathy, Toxic in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (72.73)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Albertyn, CH; Brey, N; Decloedt, EH; Esterhuizen, TM; Kellermann, TA; Nightingale, S; Sinxadi, PZ; Taljaard, JJ; van Rensburg, R1
Eastman, RW; Lee Pan, EB; Nightingale, S; Ssemmanda, S; Tucker, LM1
Allen Reeves, A; Caballero, J; Fuentes, AV; Harrington, C; Mosley Ii, JF; Thomas, JE1
Antunes, AMM; Cipriano, M; Diogo, LN; Grilo, NM; João Correia, M; Matilde Marques, M; Miranda, JP; Monteiro, EC; Pereira, SA; Serpa, J1
Dalwadi, DA; Harvey, BH; Ozuna, L; Schetz, JA; Viljoen, M1
Decloedt, EH; Maartens, G1
Ibarra-Barrueta, O; Mayo-Suarez, J; Mora-Atorrasagasti, O; Palacios-Zabalza, I1
Bisaso, KR; Ette, EI; Mukonzo, JK1
Anagnostopoulos, A; Aouri, M; Barcelo, C; Buclin, T; Cavassini, M; Decosterd, LA; Günthard, HF; Hugues, H; Rotger, M; Telenti, A; Ternon, B; Vernazza, P; Yerly, S1
Antunes, AM; Caixas, U; Correia, MJ; Diogo, LN; Grilo, NM; Harjivan, SG; Marques, MM; Monteiro, EC; Pereira, SA; Sequeira, C1
Dabaghzadeh, F; Dashti-Khavidaki, S; Ghaeli, P; Khalili, H1

Reviews

4 review(s) available for efavirenz and Encephalopathy, Toxic

ArticleYear
Neurotoxicities in the treatment of HIV between dolutegravir, rilpivirine and dolutegravir/rilpivirine: a meta-analysis.
    Sexually transmitted infections, 2021, Volume: 97, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Drug Combinations; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Neurotoxicity Syndromes; Oxazines; Piperazines; Pyridones; Randomized Controlled Trials as Topic; Rilpivirine

2021
Adverse Neuropsychiatric Events and Recreational Use of Efavirenz and Other HIV-1 Antiretroviral Drugs.
    Pharmacological reviews, 2018, Volume: 70, Issue:3

    Topics: Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Illicit Drugs; Neurotoxicity Syndromes; Reverse Transcriptase Inhibitors

2018
Neuronal toxicity of efavirenz: a systematic review.
    Expert opinion on drug safety, 2013, Volume: 12, Issue:6

    Topics: Alkynes; Animals; Benzoxazines; Brain; Calcium; Cognition Disorders; Cyclopropanes; Drug Tolerance; Humans; Neurons; Neurotoxicity Syndromes; Reverse Transcriptase Inhibitors

2013
Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:18

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cyproheptadine; Drug Interactions; Evidence-Based Medicine; HIV Seropositivity; Humans; Neurotoxicity Syndromes; Serotonin 5-HT2 Receptor Antagonists

2012

Other Studies

7 other study(ies) available for efavirenz and Encephalopathy, Toxic

ArticleYear
Pharmacogenetics of the Late-Onset Efavirenz Neurotoxicity Syndrome (LENS).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 08-31, Volume: 75, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Arylamine N-Acetyltransferase; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; HIV Infections; Humans; Isoniazid; Male; Neurotoxicity Syndromes; Pharmacogenetics; Polymorphism, Single Nucleotide

2022
Electroencephalography as a diagnostic tool for late-onset efavirenz neurotoxicity syndrome.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Adult; Case-Control Studies; Electroencephalography; Humans; Neurotoxicity Syndromes; Reproducibility of Results; Retrospective Studies

2023
Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jul-15, Volume: 105

    Topics: Alkynes; Animals; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Biotransformation; Cyclopropanes; Cytochrome P-450 CYP2B1; Hippocampus; Liver; Male; Neurotoxicity Syndromes; Prefrontal Cortex; Rats, Wistar; Steroid Hydroxylases; Sulfhydryl Compounds

2017
Effect of concomitant use of montelukast and efavirenz on neuropsychiatric adverse events.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:1

    Topics: Acetates; Adult; Alkynes; Anti-Asthmatic Agents; Anti-HIV Agents; Asthma; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Neurotoxicity Syndromes; Quinolines; Sulfides

2014
Markov model for characterizing neuropsychologic impairment and Monte Carlo simulation for optimizing efavirenz therapy.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Male; Markov Chains; Models, Biological; Monte Carlo Method; Neuropsychological Tests; Neurotoxicity Syndromes; Reverse Transcriptase Inhibitors

2015
In Vivo Profiling and Distribution of Known and Novel Phase I and Phase II Metabolites of Efavirenz in Plasma, Urine, and Cerebrospinal Fluid.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:1

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Genotype; Glucuronides; HIV Infections; Humans; Hydroxylation; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Metabolomics; Neurotoxicity Syndromes; Phenotype; Reverse Transcriptase Inhibitors; Risk Assessment; Sulfates; Tandem Mass Spectrometry

2016
Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.
    Toxicology letters, 2016, Oct-17, Volume: 260

    Topics: Adult; Alkynes; Anti-HIV Agents; Anxiety; Benzoxazines; Biomarkers, Pharmacological; Biotransformation; Blood-Brain Barrier; Case-Control Studies; CD4 Lymphocyte Count; Cyclopropanes; Drug Monitoring; Drug Therapy, Combination; Feasibility Studies; Glucuronides; HIV Infections; Humans; Male; Metabolic Detoxication, Phase II; Middle Aged; Mood Disorders; Neurotoxicity Syndromes; Prevalence; Reverse Transcriptase Inhibitors

2016