efavirenz and Elevated Cholesterol

efavirenz has been researched along with Elevated Cholesterol in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Cao, T; He, Y; Jia, X; Ju, B; Liu, J; Liu, X; Peng, Q; Rao, M; Song, Y; Sun, L; Wang, H; Wang, S; Xu, L; Zhang, H; Zhang, L; Zhang, Q; Zhao, F; Zhou, J; Zhou, Y1
Cui, X; Guo, X; Miao, X; Su, F; Ye, H1
Cofan, M; de Lazzari, E; Domingo, P; Forga, MT; Gatell, JM; González-Cordón, A; Leyes, P; Martínez, E; Negredo, E; Ros, E; Trabal, J; Vidal, F1
Greenberg, RN; Gwag, T; Helsley, RN; Meng, Z; Park, SH; Sui, Y; Wang, S; Zhou, C1
Anderson, J; Dhar, J; Ebrahimi, R; Ewan, J; Fisher, M; Moyle, GJ; Orkin, C; Wang, H; Wilkins, E1
Bednasz, C; DiFrancesco, R; Feng, Z; Fischl, MA; Gripshover, BM; Gu, J; Luque, AE; Ma, Q; Morse, GD; Venuto, CS; Zingman, BS1
Desta, Z; Hubeny, A; Jia, J; Keiser, M; Kroemer, HK; Lütjohann, D; Marinova, M; Meyer zu Schwabedissen, HE; Modess, C; Mostertz, J; Nassif, A; Ogburn, ET; Oswald, S; Runge, D; Siegmund, W; Ulrich, A1
Alonso-Villaverde, C; Camps, J; Coll, B; Gómez, F; Joven, J; Masana, L; Parra, S1
Aurpibul, L; Lee, B; Mangklabruks, A; Puthanakit, T; Sirisanthana, T; Sirisanthana, V1
Chang, SC; Chen, MY; Hsieh, SM; Hung, CC; Lu, PL1

Trials

3 trial(s) available for efavirenz and Elevated Cholesterol

ArticleYear
Increased cholesterol absorption rather than synthesis is involved in boosted protease inhibitor-associated hypercholesterolaemia.
    AIDS (London, England), 2018, 06-19, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Chemical Analysis; Cholesterol; Cyclopropanes; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; Young Adult

2018
A randomized comparative trial of continued abacavir/lamivudine plus efavirenz or replacement with efavirenz/emtricitabine/tenofovir DF in hypercholesterolemic HIV-1 infected individuals.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Adult; Alkynes; Benzoxazines; Cholesterol; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Emtricitabine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Hypercholesterolemia; Lamivudine; Male; Middle Aged; Tenofovir

2015
Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.
    Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:3

    Topics: Adult; Alkynes; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azetidines; Benzoxazines; Biological Transport; Cell Line; Cell Line, Transformed; Cyclopropanes; Cytochrome P-450 CYP3A; Dogs; Drug Interactions; Ezetimibe; Gene Expression; Glucuronosyltransferase; HEK293 Cells; HIV Infections; Humans; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; RNA, Messenger; Young Adult

2012

Other Studies

7 other study(ies) available for efavirenz and Elevated Cholesterol

ArticleYear
Higher Risk of Dyslipidemia With Coformulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide than Efavirenz, Lamivudine, and Tenofovir Disoproxil Fumarate Among Antiretroviral-Naive People Living With HIV in China.
    Journal of acquired immune deficiency syndromes (1999), 2022, 10-01, Volume: 91, Issue:S1

    Topics: Adenine; Alanine; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; Cholesterol, LDL; Cobicistat; Cyclopropanes; Emtricitabine; HIV Infections; HIV-1; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lamivudine; Lipoproteins, HDL; Quinolones; Retrospective Studies; Tenofovir

2022
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.
    Nutrition research (New York, N.Y.), 2023, Volume: 119

    Topics: Animals; Cholesterol; Fatty Liver; Hypercholesterolemia; Inflammation; Male; Mice; Pregnane X Receptor; Resveratrol

2023
Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis.
    Journal of hepatology, 2019, Volume: 70, Issue:5

    Topics: Alkynes; Animals; Benzoxazines; CD36 Antigens; Cholesterol; Cyclopropanes; Fatty Liver; Hepatocytes; Humans; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Pregnane X Receptor; Reverse Transcriptase Inhibitors; Signal Transduction; Squalene Monooxygenase

2019
Lipid-Lowering Therapy in HIV-Infected Patients: Relationship with Antiretroviral Agents and Impact of Substance-Related Disorders.
    Current vascular pharmacology, 2016, Volume: 14, Issue:3

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Dyslipidemias; Female; HIV Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Lipids; Lipodystrophy; Male; Middle Aged; Retrospective Studies; Substance-Related Disorders

2016
The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism.
    AIDS (London, England), 2005, Feb-18, Volume: 19, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cholesterol, HDL; Cyclopropanes; Female; Follow-Up Studies; Genes, MDR; Genetic Predisposition to Disease; HIV Infections; Humans; Hypercholesterolemia; Male; Middle Aged; Oxazines; Polymorphism, Genetic; Reverse Transcriptase Inhibitors

2005
Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.
    Antiviral therapy, 2007, Volume: 12, Issue:8

    Topics: Adolescent; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Lamivudine; Lipodystrophy; Male; Nevirapine; Prevalence; Reverse Transcriptase Inhibitors; Stavudine; Thailand

2007
Preliminary experience of adverse drug reactions, tolerability, and efficacy of a once-daily regimen of antiretroviral combination therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jul-01, Volume: 24, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hypercholesterolemia; Hypertriglyceridemia; Indinavir; Middle Aged; Nausea; Oxazines; Ritonavir

2000