efavirenz and Cognitive Decline

efavirenz has been researched along with Cognitive Decline in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's5 (71.43)2.80

Authors

AuthorsStudies
Bao, J; Hu, K; Li, W; Qian, F; Qiao, J; Sun, B; Zhang, R1
Bisaso, KR; Bisaso, KS; Ette, EI; Mukonzo, JK1
Alagaratnam, J; Boffito, M; Bozzali, M; Cercignani, M; Mora-Peris, B; Nelson, M; Toniolo, S; Underwood, J; Vera, JH; Winston, A1
Arends, JE; Hakkers, CS; Hermans, AM; Hoepelman, AIM; Teunissen, CE; van Maarseveen, EM; Verberk, IMW1
Bonora, S; Calcagno, A; De Benedetto, I; Guastamacchia, G; Trunfio, M1
Aklillu, E; Gustafsson, LL; Luzze, H; Mukonzo, JK; Nakasujja, N; Ogwal-Okeng, J; Okwera, A; Sebuwufu, D; Waako, P1
Clifford, DB; Collier, AC; Croteau, D; Gelman, BB; Grant, I; Heaton, RK; Kao, YT; Letendre, SL; Ma, Q; Marra, CM; McArthur, JC; Morgello, S; Sanders, CA; Simpson, DM; Vaida, F; Wong, J1

Reviews

1 review(s) available for efavirenz and Cognitive Decline

ArticleYear
A review of the potential mechanisms of neuronal toxicity associated with antiretroviral drugs.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Atazanavir Sulfate; Benzoxazines; Central Nervous System; Cognitive Dysfunction; Cyclopropanes; Dideoxynucleosides; Endothelial Cells; HIV Infections; Humans; Neurons; Nevirapine; Nitriles; Oligodendroglia; Pyrimidines

2020

Trials

1 trial(s) available for efavirenz and Cognitive Decline

ArticleYear
High efavirenz levels but not neurofilament light plasma levels are associated with poor neurocognitive functioning in asymptomatic HIV patients.
    Journal of neurovirology, 2020, Volume: 26, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Asymptomatic Diseases; Attention; Benzoxazines; Biomarkers; Cognitive Dysfunction; Cyclopropanes; Executive Function; Female; HIV Infections; Humans; Male; Mental Status and Dementia Tests; Middle Aged; Neurofilament Proteins; Rilpivirine; Speech

2020

Other Studies

5 other study(ies) available for efavirenz and Cognitive Decline

ArticleYear
Long-term efavirenz exposure induced neuroinflammation and cognitive deficits in C57BL/6 mice.
    Biochemical and biophysical research communications, 2021, 12-20, Volume: 584

    Topics: Alkynes; Animals; Benzoxazines; Cognition; Cognitive Dysfunction; Cyclopropanes; Hippocampus; Humans; Maze Learning; Memory Disorders; Mice, Inbred C57BL; Neuroinflammatory Diseases; Reverse Transcriptase Inhibitors; Spatial Learning; Synapsins; Synaptophysin; Synaptotagmin I; Time Factors

2021
Maximizing Knowledge Extraction From Patient-Reported Outcome Data Using Exposure-Outcome Item Response Modeling Approach: Understanding Efavirenz-Induced Central Nervous System Toxicity.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:6

    Topics: Alkynes; Benzoxazines; Central Nervous System; Cognitive Dysfunction; Computer Simulation; Cyclopropanes; Disease Progression; Drug Administration Schedule; Hallucinations; HIV Infections; Humans; Models, Psychological; Patient Reported Outcome Measures; Patient-Specific Modeling; Reverse Transcriptase Inhibitors; Severity of Illness Index; Sleep Wake Disorders; Symptom Assessment; Time Factors

2020
Changes in functional connectivity in people with HIV switching antiretroviral therapy.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asymptomatic Diseases; Benzoxazines; Cognitive Dysfunction; Connectome; Cyclopropanes; Drug Substitution; Emtricitabine; Executive Function; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Magnetic Resonance Imaging; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Oxazines; Piperazines; Prospective Studies; Pyridones; Raltegravir Potassium; Rilpivirine; Tenofovir

2020
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study.
    BMC infectious diseases, 2013, Jun-04, Volume: 13

    Topics: Adult; Alkynes; Anti-HIV Agents; Antibiotics, Antitubercular; Antiretroviral Therapy, Highly Active; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cognitive Dysfunction; Constitutive Androstane Receptor; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Female; Gene Frequency; Hallucinations; HIV Infections; Humans; Kaplan-Meier Estimate; Male; Memory Disorders; Mental Disorders; Prospective Studies; Rifampin; Sleep Arousal Disorders; Tuberculosis; Uganda

2013
Long-term efavirenz use is associated with worse neurocognitive functioning in HIV-infected patients.
    Journal of neurovirology, 2016, Volume: 22, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cognitive Dysfunction; Coinfection; Cyclopropanes; Drug Therapy, Combination; Executive Function; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Lopinavir; Male; Memory; Middle Aged; Neuropsychological Tests; Ritonavir; Verbal Learning

2016