efavirenz and Adverse Drug Event

efavirenz has been researched along with Adverse Drug Event in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.33)18.2507
2000's2 (6.67)29.6817
2010's23 (76.67)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Abidin, ZZ; Chidambaram, SK; Fahrni, ML; Lazzarino, AI; Misran, NFL1
Braga, MDG; Mendes, JC; Reis, AMM; Silveira, MR1
Bula, A; Chagomerana, M; Chapola, JC; Hosseinipour, MC; Lee, F; Rosenberg, NE; Tang, JH; Tseka, J1
Dai, L; Li, J; Liu, A; Mahajan, SD; Schwartz, SA; Scott, SR; Shao, Y; Su, B; Sun, L; Wu, H; Ye, J; Yu, H; Zhang, H; Zhang, T1
Brasher, WP; Bvumbwe, M; Kazembe, PN1
Aplenc, R; Bellamy, SL; Bisson, GP; Gross, R; Han, X; Moorthy, G; Mosepele, M; Ratshaa, B; Steenhoff, AP; Strom, BL; Vujkovic, M; Zuppa, AF1
Foster, C; Lyall, H; Tudor-Williams, G; Williams, E; Wynberg, E1
Bonolo, PF; Ceccato, MDGB; Costa, JO; Dos Santos, H; Mendes, JC; Reis, AMM; Silveira, MR1
Baker, P; Cardoso, CC; da Silva, GAR; de Almeida, TB; de Azevedo, MCVM; de Castro, IJ; Ferry, FRA; Haas, DW; Pinto, JFDC; Tanuri, A1
Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fox, MP; Igumbor, EU; Maartens, G1
Sukasem, C; Sungkanuparph, S1
Botes, M; Burnside, R; Clumeck, N; Cooper, DA; Dejesus, E; Heera, J; Ive, P; Lazzarin, A; Mukwaya, G; Saag, M; van Der Ryst, E; Walmsley, S1
De Castro, N; Delaugerre, C; Flandre, P; Gallien, S; Molina, JM; Nguyen, N1
Dodderi, SK; Govindaraj, M; Pavithra, HB; Premalatha, R; Rewari, BB; Sanjeeva, GN; Shivananda, S; Sukanya, V1
Aurpibul, L; Chokephaibulkit, K; Cressey, TR; Phongsamart, W; Sirisanthana, V; Sricharoenchai, S; Sudjaritruk, T; Wittawatmongkol, O1
Clotet, B; Cruceta, A; Curran, A; Domingo, P; Ferrer, E; Gatell, JM; Guardo, AC; Loncà, M; Lozano, F; Manzardo, C; Miro, JM; Pérez, I; Plana, M; Podzamczer, D1
Antinori, A; Arribas, JR; Bloch, M; Bosse, M; Chuck, SK; Cohen, CJ; De-Oertel, S; Garner, W; Piontkowsky, D; Porter, D; Rachlis, A; Rieger, A; Segal-Maurer, S; van Lunzen, J; Wohl, DA1
Beanland, R; Doherty, M; Lackey, M; Li, H; Ma, Q; Ma, W; Marley, G; Renaud, F; Tucker, JD; Vitoria, M; Wei, C1
Chêne, G; Gallien, S; Journot, V; Loriot, MA; Molina, JM; Morlat, P; Reliquet, V; Reynes, J; Sauvageon, H1
Bentley, TGK; Broder, MS; Chang, E; Myers, J; Papoyan, E; Reddy, SR; Rosenblatt, L1
Bele, V; Dravid, A; Gupte, N; Joshi, K; Pujari, S1
Dudas, K; Dumont, E; Kim, J; Lou, Y; Mayers, D; Pietropaolo, K; Piscitelli, S; St Clair, M; White, S; Zala, C; Zhou, XJ1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C1
Amaya, G; Arns da Cunha, C; Boven, K; Buelens, A; Clumeck, N; Jayaweera, D; Junod, P; Li, T; Nelson, M; Stevens, M; Tebas, P; Vanveggel, S1
Chersich, M; Fairlie, L; Kuhn, L; Meyers, T; Moultrie, H; Palmer, M1
Boven, K; Cassetti, I; Chetchotisakd, P; Cohen, CJ; Crauwels, H; Lazzarin, A; Li, T; Molina, JM; Orkin, C; Rhame, F; Rimsky, L; Stellbrink, HJ; Vanveggel, S; Williams, P1
Ainsworth, JG; Haddow, LJ; Wood, CW1
Hussar, DA1

Reviews

1 review(s) available for efavirenz and Adverse Drug Event

ArticleYear
The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis.
    AIDS and behavior, 2017, Volume: 21, Issue:2

    Topics: Adaptation, Psychological; Alkynes; Anti-HIV Agents; Benzoxazines; Counseling; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Medication Adherence; Qualitative Research

2017

Trials

8 trial(s) available for efavirenz and Adverse Drug Event

ArticleYear
Efficacy and safety of maraviroc vs. efavirenz in treatment-naive patients with HIV-1: 5-year findings.
    AIDS (London, England), 2014, Mar-13, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load; Young Adult

2014
Immune Reconstitution in Severely Immunosuppressed Antiretroviral-Naive HIV-1-Infected Patients Starting Efavirenz, Lopinavir-Ritonavir, or Atazanavir-Ritonavir Plus Tenofovir/Emtricitabine: Final 48-Week Results (The Advanz-3 Trial).
    Journal of acquired immune deficiency syndromes (1999), 2015, Jun-01, Volume: 69, Issue:2

    Topics: Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Plasma; Ritonavir; RNA, Viral; Survival Analysis; Treatment Outcome; Viral Load; Young Adult

2015
Rilpivirine vs. efavirenz-based single-tablet regimens in treatment-naive adults: week 96 efficacy and safety from a randomized phase 3b study.
    AIDS (London, England), 2016, Volume: 30, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Resistance, Viral; Drug-Related Side Effects and Adverse Reactions; Female; HIV-1; Humans; Male; Middle Aged; Quality of Life; Rilpivirine; RNA, Viral; Tablets; Treatment Outcome; Viral Load

2016
Cytochrome 2B6 polymorphism and efavirenz-induced central nervous system symptoms : a substudy of the ANRS ALIZE trial.
    HIV medicine, 2017, Volume: 18, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Cytochrome P-450 CYP2B6; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Genetic Predisposition to Disease; HIV Infections; Humans; Male; Middle Aged; Plasma; Polymorphism, Single Nucleotide

2017
Effectiveness and safety of generic fixed-dose combination of tenofovir/emtricitabine/efavirenz in HIV-1-infected patients in Western India.
    Medscape journal of medicine, 2008, Volume: 10, Issue:8

    Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Drugs, Generic; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Immunosuppression Therapy; India; Male; Middle Aged; Organophosphonates; Prevalence; Tenofovir; Treatment Outcome; Young Adult

2008
Safety and efficacy of GSK2248761, a next-generation nonnucleoside reverse transcriptase inhibitor, in treatment-naive HIV-1-infected subjects.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Argentina; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Male; Mutation; Phosphinic Acids; Placebos; Reverse Transcriptase Inhibitors; Viral Load

2012
Efficacy and safety of rilpivirine in treatment-naive, HIV-1-infected patients with hepatitis B virus/hepatitis C virus coinfection enrolled in the Phase III randomized, double-blind ECHO and THRIVE trials.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:8

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkynes; Animals; Antiviral Agents; Aspartate Aminotransferases; Benzoxazines; Coinfection; Cyclopropanes; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis C; Hepatitis C Antibodies; HIV Infections; HIV-1; Humans; Liver; Liver Function Tests; Male; Middle Aged; Nitriles; Placebos; Pyrimidines; Rilpivirine; Treatment Outcome; Young Adult

2012
Week 96 efficacy and safety of rilpivirine in treatment-naive, HIV-1 patients in two Phase III randomized trials.
    AIDS (London, England), 2013, Mar-27, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nitriles; Pyrimidines; Rilpivirine; Treatment Outcome; Young Adult

2013

Other Studies

21 other study(ies) available for efavirenz and Adverse Drug Event

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Clinical predictors of efavirenz-based regimen treatment durability: A two-year case-control study of antiretroviral-naïve patients.
    Journal of infection and public health, 2023, Volume: 16, Issue:1

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Opportunistic Infections; Retrospective Studies; Substance Abuse, Intravenous; Treatment Outcome; Viral Load

2023
Neuropsychiatric adverse drug reactions and associated factors in a cohort of individuals starting dolutegravir-based or efavirenz-based antiretroviral therapy in Belo Horizonte, Brazil.
    Current medical research and opinion, 2023, Volume: 39, Issue:4

    Topics: Benzoxazines; Brazil; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Prospective Studies

2023
Knowledge and perceptions about Dolutegravir and Dolutegravir counselling: a qualitative study among women living with HIV.
    BMC women's health, 2023, 09-09, Volume: 23, Issue:1

    Topics: Anti-Retroviral Agents; Benzoxazines; Counseling; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans

2023
Impact of Lopinavir/Ritonavir and Efavirenz-Based Antiretroviral Therapy on the Lipid Profile of Chinese HIV/AIDS Treatment-Naïve Patients in Beijing: A Retrospective Study.
    Current HIV research, 2019, Volume: 17, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Asian People; Beijing; Benzoxazines; Case-Control Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Dyslipidemias; Female; HIV Infections; Hospitals, University; Humans; Lipids; Lopinavir; Male; Middle Aged; Retrospective Studies; Ritonavir; Treatment Outcome

2019
Infection or drug toxicity? Acute ataxia and encephalopathy after uncomplicated falciparum malaria and efavirenz dose adjustment.
    Malawi medical journal : the journal of Medical Association of Malawi, 2020, Volume: 32, Issue:4

    Topics: Adolescent; Alkynes; Antiretroviral Therapy, Highly Active; Ataxia; Benzoxazines; Brain Diseases; Cyclopropanes; Diplopia; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Malaria, Falciparum; Plasmodium falciparum; Reverse Transcriptase Inhibitors

2020
CYP2B6 genotypes and early efavirenz-based HIV treatment outcomes in Botswana.
    AIDS (London, England), 2017, 09-24, Volume: 31, Issue:15

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Botswana; Cyclopropanes; Cytochrome P-450 CYP2B6; Drug-Related Side Effects and Adverse Reactions; Female; Genotype; Genotyping Techniques; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; RNA, Viral; Surveys and Questionnaires; Survival Analysis; Treatment Outcome; Viral Load; Young Adult

2017
Discontinuation of Efavirenz in Paediatric Patients: Why do Children Switch?
    Clinical drug investigation, 2018, Volume: 38, Issue:3

    Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Body Weight; CD4 Lymphocyte Count; Child; Cyclopropanes; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load

2018
Adverse reactions associated with first-line regimens in patient initiating antiretroviral therapy.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:8

    Topics: Adolescent; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Brazil; Cross-Sectional Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Male; Middle Aged; Oxazines; Piperazines; Prospective Studies; Pyridones; Quality of Life; Reverse Transcriptase Inhibitors; Tenofovir; Young Adult

2018
Drug metabolism and transport gene polymorphisms and efavirenz adverse effects in Brazilian HIV-positive individuals.
    The Journal of antimicrobial chemotherapy, 2018, 09-01, Volume: 73, Issue:9

    Topics: Adult; Aged; Alkynes; Benzoxazines; Brazil; Constitutive Androstane Receptor; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; HIV Infections; Humans; Inactivation, Metabolic; Male; Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Inhibitors

2018
Routine data underestimates the incidence of first-line antiretroviral drug discontinuations due to adverse drug reactions: Observational study in two South African cohorts.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Kaplan-Meier Estimate; Retrospective Studies; South Africa; Stavudine; Tenofovir

2018
Would a CYP2B6 test help HIV patients being treated with efavirenz?
    Pharmacogenomics, 2013, Volume: 14, Issue:9

    Topics: Alkynes; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Central Nervous System; Cyclopropanes; Cytochrome P-450 CYP2B6; Drug-Related Side Effects and Adverse Reactions; Genotype; HIV; HIV Infections; Humans; Polymorphism, Single Nucleotide; Treatment Outcome

2013
Safety and efficacy of coformulated efavirenz/emtricitabine/tenofovir single-tablet regimen in treatment-naive patients infected with HIV-1.
    Journal of medical virology, 2015, Volume: 87, Issue:2

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Emtricitabine; Europe; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Plasma; Tablets; Tenofovir; Treatment Outcome; Viral Load

2015
Nevirapine-related adverse events among children switched from efavirenz to nevirapine as compared to children who were started on nevirapine-based antiretroviral therapy directly.
    AIDS care, 2015, Volume: 27, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Incidence; India; Male; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome

2015
Efficacy, safety and pharmacokinetics of tenofovir disoproxil fumarate in virologic-suppressed HIV-infected children using weight-band dosing.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Bone Density; Calcium; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Organophosphonates; Prospective Studies; RNA, Viral; Tenofovir; Treatment Outcome; Urinalysis; Viral Load

2015
Tolerability of central nervous system symptoms among HIV-1 infected efavirenz users: analysis of patient electronic medical record data.
    AIDS care, 2017, Volume: 29, Issue:8

    Topics: Adult; Alkynes; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Electronic Health Records; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Young Adult

2017
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
Frequency of stavudine substitution due to toxicity in children receiving antiretroviral treatment in sub-Saharan Africa.
    AIDS (London, England), 2013, Mar-13, Volume: 27, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Retrospective Studies; Risk Factors; South Africa; Stavudine; Time Factors

2013
Discontinuation of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy due to nucleoside analogue reverse transcriptase inhibitor-related metabolic toxicity.
    International journal of STD & AIDS, 2007, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; United Kingdom

2007
New drugs 99, Part III.
    Nursing, 1999, Volume: 29, Issue:6

    Topics: Alkynes; Anti-HIV Agents; Antibiotics, Antitubercular; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antiviral Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Monitoring; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Etidronic Acid; Humans; Infliximab; Leprostatic Agents; Osteitis Deformans; Oxazines; Rifampin; Risedronic Acid; Thalidomide; Thionucleotides; Trastuzumab

1999