efavirenz and Acute Confusional Senile Dementia

efavirenz has been researched along with Acute Confusional Senile Dementia in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Li, Y; Mast, N; Pikuleva, IA1
Arnold, SE; Denker, J; Fortin, B; Koenig, A; Lerner, AJ; Mast, N; Maxfield, E; Pieper, AA; Pikuleva, IA; Raghupathy, S; Tatsuoka, C; Toth, ME; Trombetta, BA1
van Lier, JE1
Arakawa, H; Constans, J; Landreth, G; Li, Y; Mast, N; Maxfield, E; Pikuleva, IA; Saadane, A; Valencia-Olvera, A1
Lam, M; Li, Y; Mast, N; Maxfield, E; Moon, J; Petrov, AM; Pikuleva, IA1
Clark, M; Li, Y; Linger, M; Mast, N; Pikuleva, IA; Wiseman, J1

Trials

1 trial(s) available for efavirenz and Acute Confusional Senile Dementia

ArticleYear
CYP46A1 activation by low-dose efavirenz enhances brain cholesterol metabolism in subjects with early Alzheimer's disease.
    Alzheimer's research & therapy, 2022, 12-29, Volume: 14, Issue:1

    Topics: Alzheimer Disease; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Humans; Pilot Projects

2022

Other Studies

5 other study(ies) available for efavirenz and Acute Confusional Senile Dementia

ArticleYear
Increased Acetylcholine Levels and Other Brain Effects in 5XFAD Mice after Treatment with 8,14-Dihydroxy Metabolite of Efavirenz.
    International journal of molecular sciences, 2022, Jul-11, Volume: 23, Issue:14

    Topics: Acetylcholine; Alkynes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzoxazines; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Cyclopropanes; Disease Models, Animal; Female; Male; Mice

2022
New Therapeutic Targets for Brain Function and Disease.
    Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12

    Topics: Alkynes; Alzheimer Disease; Animals; Benzoxazines; Brain; Cholesterol 24-Hydroxylase; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Humans

2020
Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.
    Neuropharmacology, 2017, Sep-01, Volume: 123

    Topics: Administration, Oral; Alkynes; Alzheimer Disease; Animals; Benzoxazines; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Cyclopropanes; Disease Models, Animal; Female; Learning; Liver X Receptors; Male; Memory; Mice, Transgenic; Microglia; Neuroprotective Agents; Plaque, Amyloid; Transcriptome

2017
CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2019, Volume: 16, Issue:3

    Topics: Alkynes; Alzheimer Disease; Animals; Benzoxazines; Brain; Cholesterol 24-Hydroxylase; Conditioning, Classical; Cyclopropanes; Disease Models, Animal; Enzyme Activation; Female; Male; Maze Learning; Mice; Nootropic Agents; Plaque, Amyloid

2019
Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice.
    The Journal of biological chemistry, 2014, Feb-07, Volume: 289, Issue:6

    Topics: Alkynes; Alzheimer Disease; Animals; Benzoxazines; Brain; Brain Chemistry; Cattle; Cholesterol; Cholesterol 24-Hydroxylase; Cyclopropanes; Enzyme Activation; Female; HIV Infections; Male; Mice; Models, Biological; Reverse Transcriptase Inhibitors; Steroid Hydroxylases

2014