Page last updated: 2024-09-03

efaproxiral and Brain Neoplasms

efaproxiral has been researched along with Brain Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's11 (91.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Curran, W; Gaspar, L; Gerber, M; Hackman, J; Kadish, S; Mehta, M; Murray, K; Pearlman, A; Scott, C; Shaw, E; Stea, B; Suh, J1
Suh, JH1
Abajian, MA; Demidenko, E; Dunn, JF; Grinberg, OY; Hou, H; Khan, N; Lu, S; O'Hara, JA; Steffen, RP; Swartz, HM; Wilmot, CM1
Charpentier, MM1
Sneed, PK1
Boyd, AP; Cagnoni, PJ; Chang, EL; Fortin, A; Kresl, JJ; Mercier, JP; Nabid, A; Senzer, N; Shaw, E; Stea, B; Suh, JH1
Boyd, AP; Cagnoni, PJ; Shaw, E; Stea, B; Suh, JH1
Cannell, E1
Engel, RH; Kaklamani, VG1
Craig, M; Hackman, J; May, J; Pintér, T; Shaw, E; Stea, B; Steffen, RP; Suh, JH1
Hackman, J; Nabid, A; Scott, C; Stea, B; Suh, J1
Engelhard, H; Gerber, M; Grossman, SA; Kleinberg, L; Lesser, G; Pearlman, J; Piantadosi, S; Ruffer, J1

Reviews

2 review(s) available for efaproxiral and Brain Neoplasms

ArticleYear
Efaproxiral: a radiation enhancer used in brain metastases from breast cancer.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:12

    Topics: Aniline Compounds; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Propionates; Radiation-Sensitizing Agents

2005
Role of efaproxiral in metastatic brain tumors.
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:4

    Topics: Aniline Compounds; Animals; Brain Neoplasms; Breast Neoplasms; Humans; Propionates

2006

Trials

7 trial(s) available for efaproxiral and Brain Neoplasms

ArticleYear
RSR13 plus cranial radiation therapy in patients with brain metastases: comparison with the Radiation Therapy Oncology Group Recursive Partitioning Analysis Brain Metastases Database.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jun-15, Volume: 21, Issue:12

    Topics: Adult; Aged; Aniline Compounds; Brain Neoplasms; Dose Fractionation, Radiation; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Propionates; Radiation-Sensitizing Agents; Survival Analysis; Treatment Outcome

2003
Efaproxiral: a novel radiation sensitiser.
    Expert opinion on investigational drugs, 2004, Volume: 13, Issue:5

    Topics: Aniline Compounds; Animals; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Hemoglobins; Humans; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intravenous; Multicenter Studies as Topic; Oxygen; Partial Pressure; Propionates; Radiation-Sensitizing Agents

2004
Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-01, Volume: 24, Issue:1

    Topics: Adult; Aged; Aniline Compounds; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Propionates; Radiation Tolerance; Radiation-Sensitizing Agents

2006
Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival.
    International journal of radiation oncology, biology, physics, 2006, Mar-15, Volume: 64, Issue:4

    Topics: Aged; Analysis of Variance; Aniline Compounds; Brain Neoplasms; Cranial Irradiation; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Oxygen; Propionates; Radiation-Sensitizing Agents; Treatment Outcome

2006
Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases.
    British journal of cancer, 2006, Jun-19, Volume: 94, Issue:12

    Topics: Aniline Compounds; Antisickling Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Dose-Response Relationship, Drug; Erythrocytes; Female; Humans; Male; Middle Aged; Prognosis; Propionates; Survival Analysis

2006
Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral (Efaproxyn) plus whole-brain radiation therapy for brain metastases.
    American journal of clinical oncology, 2007, Volume: 30, Issue:6

    Topics: Aged; Aniline Compounds; Brain Neoplasms; Breast Neoplasms; Cranial Irradiation; Female; Humans; Middle Aged; Oxygen; Propionates; Quality of Life; Quality-Adjusted Life Years; Radiation Dosage; Radiation-Sensitizing Agents; Survival Rate

2007
Phase I trial to determine the safety, pharmacodynamics, and pharmacokinetics of RSR13, a novel radioenhancer, in newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:8

    Topics: Adult; Aged; Aniline Compounds; Antisickling Agents; Brain Neoplasms; Glioblastoma; Hemoglobins; Humans; Middle Aged; Propionates; Radiographic Image Enhancement; Survival Analysis

1999

Other Studies

3 other study(ies) available for efaproxiral and Brain Neoplasms

ArticleYear
Increased oxygenation of intracranial tumors by efaproxyn (efaproxiral), an allosteric hemoglobin modifier: In vivo EPR oximetry study.
    International journal of radiation oncology, biology, physics, 2005, Apr-01, Volume: 61, Issue:5

    Topics: Aniline Compounds; Animals; Brain Neoplasms; Cell Respiration; Hemoglobins; Male; Oxygen; Oxygen Consumption; Propionates; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344

2005
Efaproxiral: should we hold our breath?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-01, Volume: 24, Issue:1

    Topics: Aniline Compounds; Brain Neoplasms; Cell Hypoxia; Cranial Irradiation; Humans; Propionates; Radiation Tolerance; Radiation-Sensitizing Agents

2006
New hope for old drug in patients with brain metastases.
    The Lancet. Oncology, 2006, Volume: 7, Issue:2

    Topics: Aniline Compounds; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Propionates; Radiation-Sensitizing Agents

2006