Page last updated: 2024-10-26

edrophonium and Ventricular Fibrillation

edrophonium has been researched along with Ventricular Fibrillation in 2 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mitrani, RD1
Kloosterman, EM1
Huikuri, H1
Dylewski, J1
Atapattu, S1
Interian, A1
Castellanos, A1
Myerburg, RJ1
Harrison, LA1
Harrison, LH1
Kent, KM1
Epstein, SE1

Trials

1 trial available for edrophonium and Ventricular Fibrillation

ArticleYear
Muscarinic receptor stimulation with edrophonium hydrochloride does not elevate ventricular fibrillation thresholds in humans.
    Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Edrophonium; Electrocardiography; Female;

1999

Other Studies

1 other study available for edrophonium and Ventricular Fibrillation

ArticleYear
Enhancement of electrical stability of acutely ischemic myocardium by edrophonium.
    Circulation, 1974, Volume: 50, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Atropine; Cholinesterase Inhibitors; Coronary Disease;

1974