Page last updated: 2024-10-26

edrophonium and Thymoma

edrophonium has been researched along with Thymoma in 12 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"To assess the effect of oral corticosteroid therapy on the frequency of development of generalized myasthenia gravis within 2 years, the incidence of thymoma, and the amount of edrophonium needed for a positive test result in patients with ocular myasthenia gravis."3.72Development of generalized disease at 2 years in patients with ocular myasthenia gravis. ( Homel, P; Kupersmith, MJ; Latkany, R, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Yoshikawa, H1
Adachi, Y1
Nakamura, Y1
Kuriyama, N1
Murai, H1
Nomura, Y1
Sakai, Y1
Iwasa, K1
Furukawa, Y1
Kuwabara, S1
Matsui, M1
Stiefelhagen, P1
Kupersmith, MJ1
Latkany, R1
Homel, P1
Guillermo, GR1
Téllez-Zenteno, JF1
Weder-Cisneros, N1
Mimenza, A1
Estañol, B1
Remes-Troche, JM1
Cantu-Brito, C1
Shibota, Y1
Kagawa, Y1
Ottomo, M1
Sudo, K1
Wakata, N1
Sumiyoshi, S1
Tagaya, N1
Okada, S1
Araki, Y1
Kinoshita, M1
Jaklitsch, MT1
Byrne, JG1
Mery, C1
Sato, H1
Araki, S1
Black, JT1
Brait, KA1
DeJesus, PV2
Harner, RN1
Rowland, LP2
Lisak, RP1
Schotland, DL1
Berg, P1
Namba, T1
Brunner, NG1
Brown, SB1
Muguruma, M1
Grob, D1
Hannon, GT1
Bennington, JL1
Haber, SL1

Other Studies

12 other studies available for edrophonium and Thymoma

ArticleYear
Two-step nationwide epidemiological survey of myasthenia gravis in Japan 2018.
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Activities of Daily Living; Adult; Aged; Autoantibodies; Edrophonium; Esterases; Female; Humans; Imm

2022
[Surprising etiology of chronic deglutition disorder. Diagnosis at a glance in dysphagia].
    MMW Fortschritte der Medizin, 2008, Jun-05, Volume: 150, Issue:23

    Topics: Autoantibodies; Cholinesterase Inhibitors; Deglutition Disorders; Diagnosis, Differential; Edrophoni

2008
Development of generalized disease at 2 years in patients with ocular myasthenia gravis.
    Archives of neurology, 2003, Volume: 60, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antibodi

2003
Response of thymectomy: clinical and pathological characteristics among seronegative and seropositive myasthenia gravis patients.
    Acta neurologica Scandinavica, 2004, Volume: 109, Issue:3

    Topics: Adult; Autoantibodies; Disease Progression; Edrophonium; Electromyography; Female; Follow-Up Studies

2004
Thymectomy for myasthenia gravis.
    The Tohoku journal of experimental medicine, 1967, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Basal Metabolism; Calcium; Child; Child, Preschool; Chlorides; Cholinesterases; C

1967
A case of myasthenia gravis accompanied by invasive thymoma, alopecia areata and dry mouth.
    Clinical neurology and neurosurgery, 1995, Volume: 97, Issue:2

    Topics: Adult; Alopecia Areata; Edrophonium; Humans; Immune System Diseases; Magnetic Resonance Imaging; Mal

1995
Thymoma encasing last patent vein graft to the heart.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 118, Issue:3

    Topics: Combined Modality Therapy; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Edrophoni

1999
[Myasthenia gravis].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:7

    Topics: Animals; Autoantibodies; Edrophonium; Electromyography; Humans; Myasthenia Gravis; Plasma Exchange;

1990
Myasthenia gravis lacking response to cholinergic drugs.
    Neurology, 1973, Volume: 23, Issue:8

    Topics: Adrenocorticotropic Hormone; Autopsy; Diagnosis, Differential; Edrophonium; Electric Stimulation; Fe

1973
Myasthenic myopathy and thymoma.
    Neurology, 1973, Volume: 23, Issue:3

    Topics: Edrophonium; Humans; Male; Middle Aged; Muscles; Myasthenia Gravis; Neostigmine; Neuromuscular Disea

1973
Familial myasthenia gravis. Report of 27 patients in 12 families and review of 164 patients in 73 families.
    Archives of neurology, 1971, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Biopsy; Child; Child, Preschool; Consanguinity; Diseases in Tw

1971
Malignant thymoma with myasthenia and embolic metastasis; report of a case.
    Diseases of the chest, 1966, Volume: 50, Issue:6

    Topics: Ambenonium Chloride; Bronchial Neoplasms; Curare; Edrophonium; Humans; Lymphatic Metastasis; Male; M

1966