Page last updated: 2024-10-26

edrophonium and Syndrome

edrophonium has been researched along with Syndrome in 12 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
" We review six patients who presented with only DHS, responded to intravenous edrophonium and turned out to have myasthenia gravis (MG) including similar patients who were previously documented."7.79Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis. ( Eura, N; Kataoka, H; Sawa, N; Ueno, S, 2013)
" We review six patients who presented with only DHS, responded to intravenous edrophonium and turned out to have myasthenia gravis (MG) including similar patients who were previously documented."3.79Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis. ( Eura, N; Kataoka, H; Sawa, N; Ueno, S, 2013)
"Most congenital myasthenic syndromes (CMS) have postsynaptic defects from mutations within the muscle acetylcholine receptor (AChR)."1.32Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome. ( Beeson, D; Brydson, M; Croxen, R; Newsom-Davis, J; Vincent, A; Webster, R, 2004)
"In two subjects with paramyotonia congenita the isometric torque generated by the abductor digiti minimi and the surface EMG recorded over ADM decreased during prolonged or repetitive contractions, whether these were voluntarily or electrically induced."1.25Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita. ( Burke, D; Lethlean, AK; Skuse, NF, 1974)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sawa, N1
Kataoka, H1
Eura, N1
Ueno, S1
Webster, R1
Brydson, M1
Croxen, R1
Newsom-Davis, J1
Vincent, A1
Beeson, D1
Dell'Osso, LF1
Ayyar, DR1
Daroff, RB1
Abel, LA1
Dudognon, P1
Cathala, HP1
Fardeau, M1
Ribabeau-Dumas, JL1
Labrousse, G1
Sieb, JP1
Boiardi, A1
Bussone, G1
Negri, S1
Burke, WJ1
Triggs, WJ1
Beric, A1
Butler, IJ1
Roongta, SM1
Davis, TL1
Lavin, PJ1
Atienza, P1
Chaussade, S1
Hiltgen, M1
Couturier, D1
Guerre, J1
Shapira, Y1
Cividalli, G1
Szabo, G1
Rozin, R1
Russell, A1
Burke, D1
Skuse, NF1
Lethlean, AK1

Reviews

1 review available for edrophonium and Syndrome

ArticleYear
[Diagnosis and therapy of congenital myasthenia syndrome].
    Deutsche medizinische Wochenschrift (1946), 1999, Jan-08, Volume: 124, Issue:1-2

    Topics: 4-Aminopyridine; Adult; Amifampridine; Central Nervous System Stimulants; Child; Cholinesterase Inhi

1999

Other Studies

11 other studies available for edrophonium and Syndrome

ArticleYear
Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis.
    BMJ case reports, 2013, Jan-31, Volume: 2013

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Disease Progression; Edrophonium; Female; Head;

2013
Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome.
    Neurology, 2004, Apr-13, Volume: 62, Issue:7

    Topics: Adolescent; Amino Acid Sequence; Biopsy; Cell Line; DNA Mutational Analysis; Edrophonium; Electrodia

2004
Edrophonium test in Eaton-Lambert syndrome: quantitative oculography.
    Neurology, 1983, Volume: 33, Issue:9

    Topics: Aged; Edrophonium; Eye Movements; Female; Fixation, Ocular; Humans; Male; Middle Aged; Myasthenia Gr

1983
[Electromyographic and histopathological study of the Lambert-Eaton myasthenia syndrome. Apropos of a case].
    Electrodiagnostic-Therapie, 1980, Volume: 17, Issue:1

    Topics: Action Potentials; Edrophonium; Electric Stimulation; Electromyography; Humans; Male; Middle Aged; M

1980
Alternating myasthenia and myastheniform syndrome in the same subject.
    Journal of neurology, 1979, Jan-30, Volume: 220, Issue:1

    Topics: Acetylcholine; Action Potentials; Adult; Edrophonium; Humans; Male; Motor Endplate; Muscular Atrophy

1979
The ocular myasthenia syndrome.
    Proceedings of the Australian Association of Neurologists, 1975, Volume: 12

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Diagnosis, Differential; Edrophonium; Female; Humans; Male

1975
A congenital myasthenic syndrome refractory to acetylcholinesterase inhibitors.
    Muscle & nerve, 1992, Volume: 15, Issue:3

    Topics: Adult; Cholinesterase Inhibitors; Edrophonium; Electromyography; Female; Genes, Recessive; Humans; M

1992
Pseudo one-and-a-half syndrome with ocular myasthenia.
    Neurology, 1989, Volume: 39, Issue:11

    Topics: Aged; Blepharoptosis; Edrophonium; Humans; Male; Muscular Diseases; Oculomotor Muscles; Ophthalmople

1989
[A hazard of the edrophonium test (Tensilon) in vagal hypertonia syndrome].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:2

    Topics: Edrophonium; Humans; Male; Middle Aged; Muscle Hypertonia; Myocardial Contraction; Syndrome

1988
A myasthenic syndrome in childhood leukemia.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:5

    Topics: Blepharoptosis; Bone Marrow Examination; Child; Edrophonium; Electric Stimulation; Electromyography;

1974
Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:8

    Topics: Adult; Cold Temperature; Edrophonium; Electric Stimulation; Electromyography; Facial Muscles; Fatigu

1974