Page last updated: 2024-10-26

edrophonium and Respiratory Insufficiency

edrophonium has been researched along with Respiratory Insufficiency in 7 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Four severely affected patients with dysphagia as their leading symptom were examined."1.35Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis. ( Dziewas, R; Oelenberg, S; Ringelstein, EB; Teismann, I; Warnecke, T; Zimmermann, J, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BLAUGRUND, SM1
ROSIN, HD1
GENKINS, G1
OSSERMAN, KE1
Warnecke, T1
Teismann, I1
Zimmermann, J1
Oelenberg, S1
Ringelstein, EB1
Dziewas, R1
Nowakowski, JF1
Yee, AS1
Sellman, MS1
Mayer, RF1
Black, JT1
Brait, KA1
DeJesus, PV1
Harner, RN1
Rowland, LP1
Erbslöh, F1
Decker, DA1
Fincham, RW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transnasal Endoscopic Evaluation of Swallowing: Functional Esophagoscopy Using an Ultrathin Video Endoscope in Neurogenic Dysphagia[NCT01995929]62 participants (Actual)Observational2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for edrophonium and Respiratory Insufficiency

ArticleYear
[Current therapy of myasthenia gravis. I. Specific symptomatic therapy].
    Der Nervenarzt, 1972, Volume: 43, Issue:7

    Topics: Ambenonium Chloride; Anti-Bacterial Agents; Edrophonium; Enteral Nutrition; Ephedrine; Humans; Myast

1972

Other Studies

6 other studies available for edrophonium and Respiratory Insufficiency

ArticleYear
STUDIES IN MYASTHENIA GRAVIS: THE ROLE OF TRACHEOTOMY AND CONTROLLED VENTILATION.
    The Annals of otology, rhinology, and laryngology, 1964, Volume: 73

    Topics: Acidosis; Adolescent; Apnea; Autonomic Nervous System Diseases; Carbon Dioxide; Child; Cholinesteras

1964
Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis.
    Journal of neurology, 2008, Volume: 255, Issue:2

    Topics: Aged, 80 and over; Cholinesterase Inhibitors; Conscious Sedation; Deglutition; Deglutition Disorders

2008
Myasthenia Gravis.
    Annals of emergency medicine, 1982, Volume: 11, Issue:5

    Topics: Cholinesterase Inhibitors; Edrophonium; Humans; Male; Middle Aged; Muscles; Myasthenia Gravis; Respi

1982
Treatment of myasthenic crisis in late life.
    Southern medical journal, 1985, Volume: 78, Issue:10

    Topics: Adult; Aged; Cholinesterase Inhibitors; Combined Modality Therapy; Edrophonium; Female; Humans; Male

1985
Myasthenia gravis lacking response to cholinergic drugs.
    Neurology, 1973, Volume: 23, Issue:8

    Topics: Adrenocorticotropic Hormone; Autopsy; Diagnosis, Differential; Edrophonium; Electric Stimulation; Fe

1973
Respiratory arrest in myasthenia gravis with colistimethate therapy.
    Archives of neurology, 1971, Volume: 25, Issue:2

    Topics: Aged; Ampicillin; Carbenicillin; Colistin; Edrophonium; Humans; Male; Medication Errors; Myasthenia

1971