Page last updated: 2024-10-26

edrophonium and Ptosis, Eyelid

edrophonium has been researched along with Ptosis, Eyelid in 33 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Research Excerpts

ExcerptRelevanceReference
" In this study, ice test to the eyelid was evaluated as a diagnostic test on 12 myasthenic patients and 15 controls with blepharoptosis and the results were compared with those of edrophonium test."3.69Ice test as a simple diagnostic aid for myasthenia gravis. ( Araç, N; Ertaş, M; Kumral, K; Tunçbay, T, 1994)
"The case of a patient with fatigable diplopia and ptosis 3 years after removal of a large-cell lung carcinoma is presented."1.31Myasthenia gravis with a paraneoplastic marker. ( Leavitt, JA, 2000)
"The diagnosis of myasthenia gravis is usually confirmed by a Tensilon test, which can be complicated by cholinergic side effects that include cardiopulmonary arrest."1.28The sleep test for myasthenia gravis. A safe alternative to Tensilon. ( Behrens, MM; Odel, JG; Winterkorn, JM, 1991)
"A common symptom of myasthenia gravis is eyelid ptosis."1.27Ice pack test for myasthenia gravis. ( Rivner, MH; Sethi, KD; Swift, TR, 1987)
"Fifteen patients with ocular myasthenia gravis were examined in detail for 21 different signs, and tested for acetylcholine receptor antibodies."1.27An evaluation of signs in ocular myasthenia gravis and correlation with acetylcholine receptor antibodies. ( Francis, IC; Kappagoda, MB; Nicholson, GA, 1985)
"When myasthenia gravis is suspected, the presence of sustained gaze fatigue provides a tentative clinical diagnosis to be confirmed by pharmacologic testing."1.26Myasthenic sustained gaze fatigue. ( Glaser, JS; Osher, RH, 1980)
"Myasthenia gravis is characterized by variable ocular and skeletal muscle weakness."1.26The neuromuscular junction. Part II: myasthenia gravis. ( Brumback, RA, 1981)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199021 (63.64)18.7374
1990's6 (18.18)18.2507
2000's6 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sennik, DK1
Suresh, D1
Goodall, E1
Lane, RJ1
COGAN, DG1
Gamio, S1
Garcia-Erro, M1
Vaccarezza, MM1
Minella, JA1
Karatas, H1
Nurlu, G1
Kansu, T1
Gay, AJ1
Salmon, ML1
Windsor, CE1
Rush, JA1
Shafrin, F1
Shaw, JR1
Osher, RH2
Glaser, JS1
Brumback, RA1
Ertaş, M1
Araç, N1
Kumral, K1
Tunçbay, T1
Arroyo, HA1
Geh, VS1
Bradbury, JA1
Golnik, KC1
Pena, R1
Lee, AG1
Eggenberger, ER1
Wang, H1
Brown-Harrell, V1
Leavitt, JA1
Padua, L1
Stalberg, E1
LoMonaco, M1
Evoli, A1
Batocchi, A1
Tonali, P1
Guépratte, N1
Lebuisson, DA1
Brumlik, J1
Odel, JG1
Winterkorn, JM1
Behrens, MM1
Davis, TL1
Lavin, PJ1
Bartley, GB1
Bullock, JD1
Komiyama, A1
Hirayama, K1
Williams, IM1
Dickinson, P1
Sum, AC1
Gorelick, PB1
Sethi, KD1
Rivner, MH1
Swift, TR1
Francis, IC1
Nicholson, GA1
Kappagoda, MB1
Shapira, Y1
Cividalli, G1
Szabo, G1
Rozin, R1
Russell, A1
Cherington, M1
Fischer, KC1
Schwartzmann, RJ1
Kennedy, WR1
Jimenez-Pabon, E1
Retzlaff, JA1
Kearns, TP1
Howard, FM1
Cronin, ML1
Wolter, M1

Reviews

1 review available for edrophonium and Ptosis, Eyelid

ArticleYear
[Myasthenia gravis in childhood and adolescence].
    Revista de neurologia, 1996, Volume: 24, Issue:135

    Topics: Blepharoptosis; Child; Child, Preschool; Diplopia; Edrophonium; Electromyography; Female; Humans; Ma

1996

Trials

2 trials available for edrophonium and Ptosis, Eyelid

ArticleYear
An ice test for the diagnosis of myasthenia gravis.
    Ophthalmology, 1999, Volume: 106, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Blepharoptosis; Cold Temperature; Diagnostic Techniques, Ophthalmolo

1999
SFEMG in ocular myasthenia gravis diagnosis.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2000, Volume: 111, Issue:7

    Topics: Adult; Aged; Autoantibodies; Blepharoptosis; Cholinesterase Inhibitors; Diagnosis, Differential; Dip

2000

Other Studies

30 other studies available for edrophonium and Ptosis, Eyelid

ArticleYear
A case of diplopia and arm weakness.
    BMJ (Clinical research ed.), 2009, Nov-25, Volume: 339

    Topics: Aged, 80 and over; Arm; Blepharoptosis; Cholinesterase Inhibitors; Diplopia; Edrophonium; Female; Hu

2009
MYASTHENIA GRAVIS: A REVIEW OF THE DISEASE AND A DESCRIPTION OF LID TWITCH AS A CHARACTERISTIC SIGN.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 74

    Topics: Blepharoptosis; Diagnosis; Edrophonium; Electromyography; Eye Manifestations; Eyelids; Humans; Myast

1965
Myasthenia gravis in childhood.
    Binocular vision & strabismus quarterly, 2004, Volume: 19, Issue:4

    Topics: Adult; Age of Onset; Blepharoptosis; Child; Child, Preschool; Cholinesterase Inhibitors; Diagnostic

2004
Is there still a role for edrophonium in diagnosing ocular myasthenia.
    European journal of neurology, 2007, Volume: 14, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Blepharoptosis; Cholinesterase Inhibitors; Diagnosis, Differential;

2007
Hering's law, the levators, and their relationship in disease states.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Blepharoptosis; Curare; Edrophonium; Eyelids; Female; Functional Laterality; Guan

1967
Ocular myasthenia presenting as superior oblique weakness.
    Journal of clinical neuro-ophthalmology, 1982, Volume: 2, Issue:2

    Topics: Adult; Blepharoptosis; Diplopia; Edrophonium; Humans; Male; Myasthenia Gravis; Ophthalmoplegia; Stra

1982
Testing for myasthenia.
    Journal of ophthalmic nursing & technology, 1983, Volume: 2, Issue:2

    Topics: Blepharoptosis; Diplopia; Edrophonium; Humans; Myasthenia Gravis; Tonometry, Ocular

1983
Myasthenic sustained gaze fatigue.
    American journal of ophthalmology, 1980, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; Blepharoptosis; Diplopia; Edrophonium; Esotropia; Eye Movements; Fatigue; H

1980
The neuromuscular junction. Part II: myasthenia gravis.
    American family physician, 1981, Volume: 23, Issue:2

    Topics: Blepharoptosis; Cholinesterase Inhibitors; Curare; Edrophonium; Humans; Infant, Newborn; Myasthenia

1981
Ice test as a simple diagnostic aid for myasthenia gravis.
    Acta neurologica Scandinavica, 1994, Volume: 89, Issue:3

    Topics: Adolescent; Adult; Aged; Blepharoptosis; Edrophonium; Female; Humans; Ice; Male; Middle Aged; Myasth

1994
Ocular myasthenia presenting in an 11-month-old boy.
    Eye (London, England), 1998, Volume: 12 ( Pt 2)

    Topics: Autoimmune Diseases; Blepharoptosis; Cholinesterase Inhibitors; Edrophonium; Humans; Infant; Male; M

1998
The case of the droopy eye. Ocular myasthenia gravis.
    Postgraduate medicine, 1999, Volume: 106, Issue:7

    Topics: Blepharoptosis; Cholinesterase Inhibitors; Diagnosis, Differential; Edrophonium; Humans; Male; Middl

1999
Myasthenia gravis with a paraneoplastic marker.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2000, Volume: 20, Issue:2

    Topics: Autoantibodies; Azathioprine; Biomarkers; Blepharoptosis; Calcium Channels; Carcinoma, Large Cell; D

2000
[What to do in case of acquired ptosis].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Aged; Blepharoptosis; Diagnosis, Differential; Edrophonium; Female;

2002
Myasthenic "oculomotor" palsy.
    Annals of ophthalmology, 1979, Volume: 11, Issue:1

    Topics: Adult; Blepharoptosis; Diabetes Mellitus; Diabetic Neuropathies; Diagnosis, Differential; Edrophoniu

1979
Myasthenia gravis associated with wasp sting.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Blepharoptosis; Edrophonium; Humans; Hymenoptera; Insect Bites and Stings; Male; Middle Aged; Myasth

1976
The sleep test for myasthenia gravis. A safe alternative to Tensilon.
    Journal of clinical neuro-ophthalmology, 1991, Volume: 11, Issue:4

    Topics: Blepharoptosis; Child; Edrophonium; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Ophthalmop

1991
Pseudo one-and-a-half syndrome with ocular myasthenia.
    Neurology, 1989, Volume: 39, Issue:11

    Topics: Aged; Blepharoptosis; Edrophonium; Humans; Male; Muscular Diseases; Oculomotor Muscles; Ophthalmople

1989
The Tensilon test using a three-way stopcock and double syringe.
    Ophthalmic plastic and reconstructive surgery, 1986, Volume: 2, Issue:2

    Topics: Atropine; Blepharoptosis; Edrophonium; Equipment and Supplies; Equipment Design; Humans; Myasthenia

1986
Paradoxical reversal of ptosis in myasthenia gravis by edrophonium administration.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:2

    Topics: Adult; Blepharoptosis; Child; Edrophonium; Female; Humans; Myasthenia Gravis

1988
Edrophonium test in myasthenia: quantitative oculography.
    Clinical and experimental neurology, 1986, Volume: 22

    Topics: Aged; Blepharoptosis; Diagnosis, Differential; Diplopia; Edrophonium; Humans; Infrared Rays; Myasthe

1986
Office Tensilon test.
    Archives of neurology, 1987, Volume: 44, Issue:7

    Topics: Blepharoptosis; Edrophonium; Eye Diseases; Humans; Myasthenia Gravis

1987
Ice pack test for myasthenia gravis.
    Neurology, 1987, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Aged; Blepharoptosis; Cold Temperature; Edrophonium; Female; Humans; Ice; Male; M

1987
An evaluation of signs in ocular myasthenia gravis and correlation with acetylcholine receptor antibodies.
    Australian and New Zealand journal of ophthalmology, 1985, Volume: 13, Issue:4

    Topics: Adult; Aged; Autoantibodies; Blepharoptosis; Edrophonium; Humans; Middle Aged; Myasthenia Gravis; Op

1985
A myasthenic syndrome in childhood leukemia.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:5

    Topics: Blepharoptosis; Bone Marrow Examination; Child; Edrophonium; Electric Stimulation; Electromyography;

1974
Botulism. Ten-year experience.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Blepharoptosis; Botulinum Antitoxin; Botulism; Colorado; Edrophonium; Electric St

1974
Oral corticosteroids in the treatment of ocular myasthenia gravis.
    Neurology, 1974, Volume: 24, Issue:8

    Topics: Administration, Oral; Adult; Aged; Blepharoptosis; Child, Preschool; Cholinesterase Inhibitors; Edro

1974
The myasthenic syndrome associated with small cell carcinoma of the lung (Eaton-Lambert syndrome.
    Neurology, 1968, Volume: 18, Issue:8

    Topics: Action Potentials; Aged; Blepharoptosis; Carcinoma; Edrophonium; Electric Stimulation; Electromyogra

1968
Lancaster red-green test in evaluation of edrophonium effect in myasthenia gravis.
    American journal of ophthalmology, 1969, Volume: 67, Issue:1

    Topics: Adult; Aged; Blepharoptosis; Curare; Diplopia; Edrophonium; Female; Humans; Male; Methods; Myastheni

1969
[The ocular form of myasthenia].
    Deutsche medizinische Wochenschrift (1946), 1965, Nov-19, Volume: 90, Issue:47

    Topics: Adult; Aged; Blepharoptosis; Child; Curare; Edrophonium; Electromyography; Eyelids; Female; Humans;

1965