edrophonium has been researched along with Precordial Catch in 37 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edrophonium is a widely used provocative agent in the evaluation of noncardiac chest pain, with reported positivity rates of 30-55%." | 9.07 | Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain. ( Achkar, E; Falk, GW; Fleshler, B; Revta, R; Rose, S, 1993) |
| "Edrophonium chloride is used frequently as a provocative agent in the assessment of noncardiac chest pain (NCCP)." | 9.06 | Edrophonium provocative test in noncardiac chest pain. Evaluation of testing techniques. ( Castell, DO; Dalton, CB; Hewson, EG; Richter, JE, 1990) |
| "Strong esophageal contractions and not a decreased blood flow in the esophageal wall seem to be the cause of chest pain provoked by intravenous edrophonium chloride." | 7.69 | The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility. ( Gustafsson, U; Tibbling, L, 1997) |
| "1 normal hydrochloric acid, and edrophonium 80 micrograms/kg intravenously as provocative agents to reproduce chest pain and manometric alterations in 72 patients with noncardiac chest pain." | 7.67 | Prospective evaluation of high-dose bethanechol in investigation of esophageal chest pain. ( Benjamin, SB; Cattau, EL; Deschner, WK; Maher, KA, 1989) |
| "Edrophonium is a widely used provocative agent in the evaluation of noncardiac chest pain, with reported positivity rates of 30-55%." | 5.07 | Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain. ( Achkar, E; Falk, GW; Fleshler, B; Revta, R; Rose, S, 1993) |
| "1 N hydrochloric acid) and edrophonium (80 micrograms/kg intravenously) tests were placebo-controlled with a positive study defined as replication of typical chest pain." | 5.07 | Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain. ( Dalton, CB; Hewson, EG; Richter, JE; Sinclair, JW, 1991) |
| "Edrophonium chloride is used frequently as a provocative agent in the assessment of noncardiac chest pain (NCCP)." | 5.06 | Edrophonium provocative test in noncardiac chest pain. Evaluation of testing techniques. ( Castell, DO; Dalton, CB; Hewson, EG; Richter, JE, 1990) |
| "Strong esophageal contractions and not a decreased blood flow in the esophageal wall seem to be the cause of chest pain provoked by intravenous edrophonium chloride." | 3.69 | The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility. ( Gustafsson, U; Tibbling, L, 1997) |
| "We combined edrophonium provocative testing with the technique of radionuclide oesophageal transit (RET) in 30 consecutive patients with non-cardiac chest pain (NCCP) and 12 controls." | 3.68 | The clinical utility of provocative radionuclide oesophageal transit in the evaluation of non-cardiac chest pain. ( Elloway, RS; Jacobs, MP; Mantil, JC; Nathan, MF, 1992) |
| "Fourty-four unselected patients with noncardiac chest pain were studied using conventional manometry with additional edrophonium provocation and 24-hour ambulatory esophageal pH and pressure recording with a system developed by our group." | 3.68 | Analysis of 24-hour esophageal pressure and pH data in unselected patients with noncardiac chest pain. ( Akkermans, LM; Breumelhof, R; Nadorp, JH; Smout, AJ, 1990) |
| "1 normal hydrochloric acid, and edrophonium 80 micrograms/kg intravenously as provocative agents to reproduce chest pain and manometric alterations in 72 patients with noncardiac chest pain." | 3.67 | Prospective evaluation of high-dose bethanechol in investigation of esophageal chest pain. ( Benjamin, SB; Cattau, EL; Deschner, WK; Maher, KA, 1989) |
| " Our aim was to determine prospectively the incidence of esophageal disorders and abnormal responses to edrophonium chloride and esophageal acid infusions in patients with MVP and troublesome non-ischemic chest pain." | 3.67 | Esophageal dysfunction and chest pain in patients with mitral valve prolapse: a prospective study utilizing provocative testing during esophageal manometry. ( Davidson, WR; Day, FP; Koch, KL; Spears, PF; Voss, SR, 1989) |
| "A 44." | 1.32 | Prevalence of esophageal disorders in patients with recurrent chest pain. ( Barroso, MS; Losada, H; Manterola, C; Muñoz, S; Vial, M, 2004) |
| "Edrophonium continues to be a relatively sensitive test for noncardiac chest pain." | 1.27 | Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain. ( Hendrix, EA; Nasrallah, SM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (29.73) | 18.7374 |
| 1990's | 23 (62.16) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fass, R | 1 |
| Manterola, C | 1 |
| Barroso, MS | 1 |
| Losada, H | 1 |
| Muñoz, S | 1 |
| Vial, M | 1 |
| Trujillo, L | 1 |
| Hernández, MC | 1 |
| Leo, E | 1 |
| Just, RJ | 1 |
| Castell, DO | 5 |
| Rose, S | 2 |
| Achkar, E | 2 |
| Easley, KA | 1 |
| Anselmino, M | 1 |
| Clark, GW | 1 |
| Hinder, RA | 1 |
| Li, H | 1 |
| Zhang, XD | 1 |
| Falk, GW | 1 |
| Fleshler, B | 1 |
| Revta, R | 1 |
| Frøbert, O | 1 |
| Funch-Jensen, P | 1 |
| Bagger, JP | 1 |
| Gustafsson, U | 1 |
| Tibbling, L | 1 |
| Cooke, RA | 1 |
| Anggiansah, A | 2 |
| Chambers, JB | 1 |
| Owen, WJ | 2 |
| Balaban, DH | 1 |
| Yamamoto, Y | 1 |
| Liu, J | 1 |
| Pehlivanov, N | 1 |
| Wisniewski, R | 1 |
| DeSilvey, D | 1 |
| Mittal, RK | 1 |
| Hookman, P | 1 |
| Barkin, JS | 1 |
| Rokkas, T | 1 |
| McCullagh, M | 1 |
| Elloway, RS | 1 |
| Jacobs, MP | 1 |
| Nathan, MF | 1 |
| Mantil, JC | 1 |
| de Caestecker, JS | 2 |
| Pryde, A | 2 |
| Heading, RC | 2 |
| Deschner, WK | 2 |
| Maher, KA | 2 |
| Cattau, EL | 2 |
| Benjamin, SB | 2 |
| Hewson, EG | 4 |
| Sinclair, JW | 1 |
| Dalton, CB | 5 |
| Richter, JE | 7 |
| Hackshaw, BT | 1 |
| Wu, WC | 2 |
| Breumelhof, R | 2 |
| Nadorp, JH | 2 |
| Akkermans, LM | 2 |
| Smout, AJ | 2 |
| Humeau, B | 1 |
| Cloarec, D | 1 |
| Simon, J | 1 |
| Bruley des Varannes, S | 1 |
| Le Bodic, L | 1 |
| Bouhour, JB | 1 |
| Galmiche, JP | 1 |
| Apollonio, G | 1 |
| Dederding, JP | 1 |
| Bosson, R | 1 |
| Baumann, R | 1 |
| Loup, R | 1 |
| Girard, L | 1 |
| Miazza, B | 1 |
| de Peyer, R | 1 |
| Loizeau, E | 1 |
| Ghillebert, G | 1 |
| Janssens, J | 2 |
| Vantrappen, G | 2 |
| Nevens, F | 1 |
| Piessens, J | 1 |
| Limburg, AJ | 1 |
| Beekhuis, H | 1 |
| van Dijk, RB | 1 |
| Kleibeuker, JH | 1 |
| Soffer, EE | 1 |
| Scalabrini, P | 1 |
| Wingate, DL | 1 |
| Breedijk, M | 1 |
| Koch, KL | 1 |
| Davidson, WR | 1 |
| Day, FP | 1 |
| Spears, PF | 1 |
| Voss, SR | 1 |
| Nasrallah, SM | 1 |
| Hendrix, EA | 1 |
| Lee, CA | 1 |
| Reynolds, JC | 1 |
| Ouyang, A | 1 |
| Baker, L | 1 |
| Cohen, S | 1 |
| Barish, CF | 1 |
| Katz, PO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Esophageal Motility Disorders in Patients With Non-cardiac Chest Pain at Assiut University Hospital[NCT05402462] | 90 participants (Anticipated) | Observational | 2022-06-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for edrophonium and Precordial Catch
| Article | Year |
|---|---|
Evaluation and diagnosis of noncardiac chest pain.
Topics: Chest Pain; Cholinesterase Inhibitors; Edrophonium; Endoscopy, Gastrointestinal; Ergonovine; Esophag | 2008 |
Chest pain of undetermined origin.
Topics: Barium Sulfate; Chest Pain; Clinical Trials as Topic; Combined Modality Therapy; Drug Therapy, Combi | 1994 |
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E | 1993 |
[Current status of the diagnosis of esophageal chest pain].
Topics: Angina Pectoris; Chest Pain; Diagnosis, Differential; Edrophonium; Electrocardiography; Esophageal M | 1993 |
5 trials available for edrophonium and Precordial Catch
| Article | Year |
|---|---|
Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain.
Topics: Adult; Aged; Chest Pain; Coronary Angiography; Edrophonium; Esophageal Diseases; Female; Humans; Mal | 1993 |
Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography.
Topics: Adolescent; Adult; Aged; Chest Pain; Deglutition; Edrophonium; Esophageal Motility Disorders; Esopha | 1999 |
Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain.
Topics: Adult; Aged; Ambulatory Care; Chest Pain; Edrophonium; Evaluation Studies as Topic; Female; Gastroes | 1991 |
Edrophonium provocative test in noncardiac chest pain. Evaluation of testing techniques.
Topics: Body Weight; Chest Pain; Edrophonium; Esophageal Motility Disorders; Esophagus; Female; Humans; Male | 1990 |
Graded esophageal balloon distention. A new provocative test for noncardiac chest pain.
Topics: Acids; Adult; Aged; Catheterization; Chest Pain; Diagnosis, Differential; Edrophonium; Esophageal Di | 1986 |
28 other studies available for edrophonium and Precordial Catch
| Article | Year |
|---|---|
Prevalence of esophageal disorders in patients with recurrent chest pain.
Topics: Adult; Aged; Aged, 80 and over; Chest Pain; Cross-Sectional Studies; Diagnosis, Differential; Edroph | 2004 |
[Thoracic pain caused by esophageal dysfunction in patients with ischemic cardiopathy].
Topics: Acids; Adult; Aged; Angina Pectoris; Chest Pain; Diagnosis, Differential; Edrophonium; Esophageal Mo | 2007 |
Follow-up of patients with noncardiac chest pain. Value of esophageal testing.
Topics: Adult; Aged; Chest Pain; Chi-Square Distribution; Edrophonium; Esophagus; Female; Follow-Up Studies; | 1994 |
Diagnostic value of esophageal studies in patients with angina-like chest pain and normal coronary angiograms.
Topics: Adolescent; Adult; Aged; Chest Pain; Coronary Angiography; Cross-Sectional Studies; Edrophonium; Ele | 1996 |
The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility.
Topics: Adult; Aged; Chest Pain; Cholinesterase Inhibitors; Edrophonium; Esophageal Motility Disorders; Esop | 1997 |
A prospective study of oesophageal function in patients with normal coronary angiograms and controls with angina.
Topics: Angina Pectoris; Case-Control Studies; Chest Pain; Cholinesterase Inhibitors; Coronary Angiography; | 1998 |
The diagnosis and management of unexplained chest pain--is less more?
Topics: Angina Pectoris; Chest Pain; Coronary Angiography; Coronary Disease; Diagnosis, Differential; Edroph | 1999 |
Acid perfusion and edrophonium provocation tests in patients with chest pain of undetermined etiology.
Topics: Adult; Aged; Chest Pain; Chi-Square Distribution; Circadian Rhythm; Diagnosis, Differential; Edropho | 1992 |
The clinical utility of provocative radionuclide oesophageal transit in the evaluation of non-cardiac chest pain.
Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophageal Motility Disorders; Esophagus; Female; Huma | 1992 |
Site and mechanism of pain perception with oesophageal balloon distension and intravenous edrophonium in patients with oesophageal chest pain.
Topics: Adult; Atropine; Catheterization; Chest Pain; Edrophonium; Esophageal Motility Disorders; Esophagus; | 1992 |
Intraesophageal balloon distention versus drug provocation in the evaluation of noncardiac chest pain.
Topics: Bethanechol; Bethanechol Compounds; Catheterization; Chest Pain; Coronary Disease; Deglutition Disor | 1990 |
The prevalence of abnormal esophageal test results in patients with cardiovascular disease and unexplained chest pain.
Topics: Acids; Adult; Aged; Angioplasty, Balloon; Cardiovascular Diseases; Chest Pain; Coronary Artery Bypas | 1990 |
Analysis of 24-hour esophageal pressure and pH data in unselected patients with noncardiac chest pain.
Topics: Adult; Chest Pain; Edrophonium; Esophageal Motility Disorders; Esophagus; Female; Gastroesophageal R | 1990 |
Comparison of esophageal manometry, provocative testing, and ambulatory monitoring in patients with unexplained chest pain.
Topics: Chest Pain; Edrophonium; Esophageal Motility Disorders; Esophagus; Female; Humans; Hydrogen-Ion Conc | 1990 |
[Pseudo-angina pain of esophageal origin. Results of functional study and value of the balloon distention test].
Topics: Adult; Aged; Angina Pectoris; Chest Pain; Diagnosis, Differential; Edrophonium; Esophageal Diseases; | 1990 |
[Questionable usefulness of the edrophonium test in the diagnosis of non-cardiac retrosternal pain].
Topics: Adult; Aged; Aged, 80 and over; Chest Pain; Edrophonium; Esophageal Motility Disorders; False Positi | 1990 |
Ambulatory 24 hour intraoesophageal pH and pressure recordings v provocation tests in the diagnosis of chest pain of oesophageal origin.
Topics: Adult; Aged; Ambulatory Care; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Human | 1990 |
Noncardiac chest pain: is the esophagus really a frequent source?
Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophagoscopy; Female; Gastroesophageal Reflux; Humans | 1990 |
[Role of manometry in the diagnosis of motor disorders of the esophagus].
Topics: Chest Pain; Deglutition Disorders; Diagnosis, Differential; Edrophonium; Esophageal Diseases; Esopha | 1989 |
Prospective evaluation of high-dose bethanechol in investigation of esophageal chest pain.
Topics: Bethanechol; Bethanechol Compounds; Chest Pain; Edrophonium; Esophageal Motility Disorders; Female; | 1989 |
Spontaneous noncardiac chest pain: value of ambulatory esophageal pH and motility monitoring.
Topics: Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophageal Motility Disorders; Female; Hu | 1989 |
[The value of ambulatory 24-hour esophageal manometry in the diagnosis of retrosternal pain of non-cardiac origin].
Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Hydrogen-Ion Concentration; | 1989 |
Esophageal dysfunction and chest pain in patients with mitral valve prolapse: a prospective study utilizing provocative testing during esophageal manometry.
Topics: Adult; Aged; Chest Pain; Echocardiography; Edrophonium; Esophageal Motility Disorders; Esophagus; Fe | 1989 |
Comparison of intravenous edrophonium and oesophageal acid perfusion during oesophageal manometry in patients with non-cardiac chest pain.
Topics: Adolescent; Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Hy | 1988 |
Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain.
Topics: Adolescent; Adult; Aged; Chest Pain; Deglutition Disorders; Diagnosis, Differential; Edrophonium; Es | 1987 |
Esophageal chest pain. Value of high-dose provocative testing with edrophonium chloride in patients with normal esophageal manometries.
Topics: Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Male; Manometr | 1987 |
Edrophonium testing for esophageal pain. Concurrence and discord.
Topics: Chest Pain; Edrophonium; Esophagus; Humans; Manometry; Pain | 1987 |
Esophageal testing of patients with noncardiac chest pain or dysphagia. Results of three years' experience with 1161 patients.
Topics: Acids; Adolescent; Adult; Aged; Aged, 80 and over; Chest Pain; Deglutition Disorders; Edrophonium; E | 1987 |