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edrophonium and Postpoliomyelitis Syndrome

edrophonium has been researched along with Postpoliomyelitis Syndrome in 3 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Postpoliomyelitis Syndrome: A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cashman, NR3
Trojan, DA3
Gendron, D1

Other Studies

3 other studies available for edrophonium and Postpoliomyelitis Syndrome

ArticleYear
Correlation of electrophysiology with pathology, pathogenesis, and anticholinesterase therapy in post-polio syndrome.
    Annals of the New York Academy of Sciences, 1995, May-25, Volume: 753

    Topics: Acetylcholinesterase; Action Potentials; Biopsy; Cell Adhesion Molecules, Neuronal; Edrophonium; Ele

1995
Anticholinesterases in post-poliomyelitis syndrome.
    Annals of the New York Academy of Sciences, 1995, May-25, Volume: 753

    Topics: Edrophonium; Electromyography; Fatigue; Humans; Muscle Contraction; Neuromuscular Junction; Postpoli

1995
Anticholinesterase-responsive neuromuscular junction transmission defects in post-poliomyelitis fatigue.
    Journal of the neurological sciences, 1993, Volume: 114, Issue:2

    Topics: Adult; Aged; Edrophonium; Electric Stimulation; Electromyography; Fatigue; Humans; Middle Aged; Musc

1993