edrophonium has been researched along with Palsy in 11 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although edrophonium does not alter plasma cholinesterase activity, we have observed that doses of edrophonium that antagonize paralysis from other nondepolarizing muscle relaxants are less effective with mivacurium." | 7.69 | Edrophonium increases mivacurium concentrations during constant mivacurium infusion, and large doses minimally antagonize paralysis. ( Brown, R; Fisher, DM; Gruenke, L; Hart, PS; Lau, M; Miller, RD; Sharma, ML; Wright, PM, 1995) |
| " Although edrophonium does not alter plasma cholinesterase activity, we have observed that doses of edrophonium that antagonize paralysis from other nondepolarizing muscle relaxants are less effective with mivacurium." | 3.69 | Edrophonium increases mivacurium concentrations during constant mivacurium infusion, and large doses minimally antagonize paralysis. ( Brown, R; Fisher, DM; Gruenke, L; Hart, PS; Lau, M; Miller, RD; Sharma, ML; Wright, PM, 1995) |
| "Benzoquinonium (Mytolon) has been shown to produce a curare-like rather than a decamethonium-like paralysis of neuromuscular transmission in the tibialis anterior and soleus muscle of cats and the gastrocnemius muscle of hens." | 3.63 | The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen. ( BOWMAN, WC, 1958) |
| "Edrophonium was administered in incremental doses intravenously either until the fade ratio increased to 0." | 1.26 | Edrophonium antagonism of pancuronium-induced neuromuscular blockade in man: a reappraisal. ( Kopman, AF, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BOWMAN, WC | 1 |
| KLEE, A | 1 |
| JACOBSEN, B | 1 |
| MIWA, S | 1 |
| SHIMURA, S | 1 |
| Warrell, DA | 1 |
| Looareesuwan, S | 1 |
| White, NJ | 1 |
| Theakston, RD | 1 |
| Warrell, MJ | 1 |
| Kosakarn, W | 1 |
| Reid, HA | 1 |
| Hart, PS | 1 |
| Wright, PM | 1 |
| Brown, R | 1 |
| Lau, M | 1 |
| Sharma, ML | 1 |
| Miller, RD | 1 |
| Gruenke, L | 1 |
| Fisher, DM | 1 |
| Blythe, JA | 1 |
| Griffin, JP | 1 |
| Gonyea, EF | 1 |
| Kopman, AF | 1 |
| Hennart, D | 1 |
| d'Hollander, A | 1 |
| Plasman, C | 1 |
| De Jonckheere, M | 1 |
| Patrick, J | 1 |
| Lindstrom, J | 1 |
| Torda, TA | 1 |
| Sinclair, E | 1 |
| Ulyatt, DB | 1 |
| Capetola, R | 1 |
| Ferko, AP | 1 |
| Calesnick, B | 1 |
11 other studies available for edrophonium and Palsy
| Article | Year |
|---|---|
The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen.
Topics: Acetylcholine; Animals; Cats; Chickens; Cholinesterase Inhibitors; Cholinesterases; Edrophonium; Fem | 1958 |
Side effects of the edrophonium chloride (Tensilon) test. Report of an unusual case.
Topics: Cardiovascular Agents; Edrophonium; Humans; Muscle Relaxants, Central; Musculoskeletal System; Paral | 1962 |
[Cure of motor paralysis with anticholinesterase drugs. Examination by induced electromyography and experimental use of Antirex].
Topics: Cardiovascular Agents; Cholinesterase Inhibitors; Edrophonium; Electromyography; Humans; Muscle Rela | 1962 |
Severe neurotoxic envenoming by the Malayan krait Bungarus candidus (Linnaeus): response to antivenom and anticholinesterase.
Topics: Adolescent; Adult; Antivenins; Bungarotoxins; Child; Cholinesterase Inhibitors; Edrophonium; Female; | 1983 |
Edrophonium increases mivacurium concentrations during constant mivacurium infusion, and large doses minimally antagonize paralysis.
Topics: Adolescent; Adult; Cholinesterases; Dose-Response Relationship, Drug; Drug Interactions; Edrophonium | 1995 |
Bilateral diaphragmatic paralysis in association with neurogenic disease.
Topics: Brachial Plexus; Chronic Disease; Diaphragm; Edrophonium; Humans; Male; Middle Aged; Paralysis; Peri | 1977 |
Edrophonium antagonism of pancuronium-induced neuromuscular blockade in man: a reappraisal.
Topics: Edrophonium; Evoked Potentials; Humans; Neuromuscular Junction; Pancuronium; Paralysis; Receptors, D | 1979 |
Importance of the level of paralysis recovery for a rapid antagonism of atracurium neuromuscular blockade with moderate doses of edrophonium.
Topics: Adult; Anesthesia, General; Atracurium; Edrophonium; Humans; Isoquinolines; Muscles; Neuromuscular B | 1986 |
Autoimmune response to acetylcholine receptor.
Topics: Animals; Antibody Formation; Antigens; Autoimmune Diseases; Edrophonium; Eels; Electric Organ; Elect | 1973 |
Puffer fish (tetrodotoxin) poisoning: clinical record and suggested management.
Topics: Adolescent; Animals; Arrhythmias, Cardiac; Consciousness; Edrophonium; Fishes, Poisonous; Foodborne | 1973 |
The inhibitory action of dopamine on the rat anterior tibialis muscle preparation.
Topics: Animals; Anura; Chlorpromazine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Ed | 1974 |