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edrophonium and Nerve Degeneration

edrophonium has been researched along with Nerve Degeneration in 3 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hall, ED1
Riker, WF2
Baker, T1
Drakontides, AB1
Welch, LK1
Appenzeller, O1
Bicknell, JM1

Other Studies

3 other studies available for edrophonium and Nerve Degeneration

ArticleYear
Glucocorticoid effects on the edrophonium responsiveness of normal and degenerating mammalian motor nerve terminals.
    Annals of neurology, 1977, Volume: 2, Issue:5

    Topics: Animals; Axons; Cats; Edrophonium; Evoked Potentials; Muscle Contraction; Nerve Degeneration; Neurom

1977
Functional, pharmacologic, and ultrastructural correlates in degenerating rat motor nerve terminals.
    Experimental neurology, 1978, Volume: 59, Issue:1

    Topics: Animals; Edrophonium; Evoked Potentials; Male; Motor Neurons; Muscle Contraction; Nerve Degeneration

1978
Peripheral neuropathy with myokymia, sustained muscular contraction, and continuous motor unit activity.
    Neurology, 1972, Volume: 22, Issue:2

    Topics: Action Potentials; Adult; Calcium; Decamethonium Compounds; Demyelinating Diseases; Edrophonium; Ele

1972