Page last updated: 2024-10-26

edrophonium and Myotonic Dystrophy

edrophonium has been researched along with Myotonic Dystrophy in 3 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.

Research Excerpts

ExcerptRelevanceReference
"A 53-year-old man with dystrophia myotonica developed symptoms of a chronic intestinal motility disorder."1.26Gastroduodenal motility in a case of dystrophia myotonica. ( Daniel, EE; Lewis, TD, 1981)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lewis, TD1
Daniel, EE1
Brown, JC1
Satoyoshi, E1
Kinoshita, M1
Doi, Y1
Nakazato, H1

Other Studies

3 other studies available for edrophonium and Myotonic Dystrophy

ArticleYear
Gastroduodenal motility in a case of dystrophia myotonica.
    Gastroenterology, 1981, Volume: 81, Issue:1

    Topics: Duodenum; Edrophonium; Food; Gastrointestinal Motility; Humans; Intestinal Obstruction; Male; Manome

1981
Muscle weakness after rest in myotonic disorders; an electrophysiological study.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:12

    Topics: Action Potentials; Adult; Edrophonium; Electric Stimulation; Electromyography; Guanidines; Humans; M

1974
[Electrophysiological study on myasthenia gravis--studies by subliminal double electrical stimulation].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1971, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Edrophonium; Electric Stimulation; Electromyography; Female; Humans; Male; Middle

1971