Page last updated: 2024-10-26

edrophonium and Muscular Atrophy

edrophonium has been researched along with Muscular Atrophy in 4 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.

Research Excerpts

ExcerptRelevanceReference
"Two cases of severe myasthenia gravis are described, with histological findings."1.25Neurogenic muscle atrophy in myasthenia gravis. ( Brownell, B; Oppenheimer, DR; Spalding, JM, 1972)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRODY, IA1
ENGEL, WK1
Boiardi, A1
Bussone, G1
Negri, S1
Smith, JL1
Brownell, B1
Oppenheimer, DR1
Spalding, JM1

Other Studies

4 other studies available for edrophonium and Muscular Atrophy

ArticleYear
DENERVATION OF MUSCLE IN MYASTHENIA GRAVIS. ROPORT OF A PATIENT WITH MYASTHENIA GRAVIS FOR 47 YEARS AND HISTOCHEMICAL SIGNS OF DENERVATION.
    Archives of neurology, 1964, Volume: 11

    Topics: Adenosine Triphosphatases; Biopsy; Edrophonium; Eyelids; Histocytochemistry; Humans; Muscle Denervat

1964
Alternating myasthenia and myastheniform syndrome in the same subject.
    Journal of neurology, 1979, Jan-30, Volume: 220, Issue:1

    Topics: Acetylcholine; Action Potentials; Adult; Edrophonium; Humans; Male; Motor Endplate; Muscular Atrophy

1979
Myasthenia gravis and Charcot-Marie-Tooth disease.
    Journal of clinical neuro-ophthalmology, 1985, Volume: 5, Issue:2

    Topics: Adult; Aged; Charcot-Marie-Tooth Disease; Edrophonium; Eye Diseases; Humans; Male; Muscular Atrophy;

1985
Neurogenic muscle atrophy in myasthenia gravis.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Edrophonium; Electromyography; Humans; Larynx; Male; Muscles; Mu

1972