Page last updated: 2024-10-26

edrophonium and Muscle Weakness

edrophonium has been researched along with Muscle Weakness in 5 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Muscle Weakness: A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)

Research Excerpts

ExcerptRelevanceReference
" We review six patients who presented with only DHS, responded to intravenous edrophonium and turned out to have myasthenia gravis (MG) including similar patients who were previously documented."7.79Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis. ( Eura, N; Kataoka, H; Sawa, N; Ueno, S, 2013)
" We review six patients who presented with only DHS, responded to intravenous edrophonium and turned out to have myasthenia gravis (MG) including similar patients who were previously documented."3.79Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis. ( Eura, N; Kataoka, H; Sawa, N; Ueno, S, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benjamin, LA1
Chipolombwe, J1
Domargard, K1
Sawa, N1
Kataoka, H1
Eura, N1
Ueno, S1
Shankar, A1
Solomon, T1
Joseph, TP1
Gnanamuthu, C1
Yaguchi, H1
Takei, A1
Honma, S1
Yamashita, I1
Doi, S1
Hamada, T1
Ngeh, JK1
McElligott, G1

Other Studies

5 other studies available for edrophonium and Muscle Weakness

ArticleYear
Case report: A young man with progressive weakness, double vision and breathlessness.
    Malawi medical journal : the journal of Medical Association of Malawi, 2011, Volume: 23, Issue:3

    Topics: Adolescent; Cholinesterase Inhibitors; Diplopia; Dyspnea; Edrophonium; Humans; Male; Muscle Weakness

2011
Dropped head with positive intravenous edrophonium, progressing to myasthenia gravis.
    BMJ case reports, 2013, Jan-31, Volume: 2013

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Disease Progression; Edrophonium; Female; Head;

2013
Autosomal recessive limb girdle myasthenia in two sisters.
    Neurology India, 2002, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Cholinesterase Inhibitors; Drug Therapy, Combination; Edrophonium; Female; Genes,

2002
Dropped head sign as the only symptom of myasthenia gravis.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:11

    Topics: Cholinesterase Inhibitors; Edrophonium; Electromyography; Head; Humans; Male; Middle Aged; Muscle We

2007
Myasthenia gravis: an elusive diagnosis in older people.
    Journal of the American Geriatrics Society, 2001, Volume: 49, Issue:5

    Topics: Accidental Falls; Age Factors; Aged; Aged, 80 and over; Cognition Disorders; Deglutition Disorders;

2001