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edrophonium and Muscle Relaxation

edrophonium has been researched along with Muscle Relaxation in 4 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"08 mg/kg), 36 surgical patients undergoing barbiturate/halothane anesthesia were given edrophonium 0."3.67[Antagonism of an intubation dose of vecuronium]. ( Baar, H; Lazarus, G; Sold, M, 1987)
"Atracurium did not cause cardiovascular changes."1.27Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane. ( Arpin, D; Hildebrand, SV, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, L1
Jayarajah, MJ1
Toner, CC1
Flynn, PJ1
Hashimoto, Y1
Shima, T1
Matsukawa, S1
Sold, M1
Lazarus, G1
Baar, H1
Hildebrand, SV1
Arpin, D1

Trials

1 trial available for edrophonium and Muscle Relaxation

ArticleYear
Evaluation of neuromuscular effects and antagonism of rocuronium bromide: a preliminary report.
    European journal of anaesthesiology. Supplement, 1995, Volume: 11

    Topics: Adolescent; Adult; Androstanols; Anesthesia; Cholinesterase Inhibitors; Double-Blind Method; Edropho

1995

Other Studies

3 other studies available for edrophonium and Muscle Relaxation

ArticleYear
Effect of plasma-cholinesterase preparation on the phase II block of succinylcholine chloride in man.
    The Tohoku journal of experimental medicine, 1977, Volume: 122, Issue:3

    Topics: Adult; Cholinesterases; Edrophonium; Humans; Muscle Relaxation; Succinylcholine

1977
[Antagonism of an intubation dose of vecuronium].
    Der Anaesthesist, 1987, Volume: 36, Issue:7

    Topics: Anesthesia; Edrophonium; Halothane; Humans; Intubation; Muscle Contraction; Muscle Relaxation; Neost

1987
Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane.
    American journal of veterinary research, 1988, Volume: 49, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Atracurium; Blood Pressure; Edrophonium; Halothane; Heart Rate; Hor

1988