Page last updated: 2024-10-26

edrophonium and Muscle Disorders

edrophonium has been researched along with Muscle Disorders in 16 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Grandis, D1
Mezzina, C1
Fiaschi, A1
Pinelli, P2
Bazzato, G1
Morachiello, M1
Dudognon, P1
Cathala, HP1
Fardeau, M1
Ribabeau-Dumas, JL1
Labrousse, G1
Padua, L1
Stalberg, E1
LoMonaco, M1
Evoli, A1
Batocchi, A1
Tonali, P1
Arrigo, A1
Moglia, A1
Davis, TL1
Lavin, PJ1
Chagnac, Y1
Hadani, M1
Goldhammer, Y1
Lücking, CH1
Struppler, A1
Bradley, WG1
Jenkison, M1
Park, DC1
Hudgson, P1
Gardner-Medwin, D1
Pennington, RJ1
Walton, JN1
Wray, SH1
Pavan-Langston, D1
Welch, LK1
Appenzeller, O1
Bicknell, JM1
Grob, D1
Namba, T1
Feldman, DS1
Shapira, Y1
Cividalli, G1
Szabo, G1
Rozin, R1
Russell, A1
Tenser, RB1
Corbett, JJ1
Oh, SJ1
Schwab, RS1
Perlo, VP1
Kennedy, WR1
Jimenez-Pabon, E1

Trials

1 trial available for edrophonium and Muscle Disorders

ArticleYear
SFEMG in ocular myasthenia gravis diagnosis.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2000, Volume: 111, Issue:7

    Topics: Adult; Aged; Autoantibodies; Blepharoptosis; Cholinesterase Inhibitors; Diagnosis, Differential; Dip

2000

Other Studies

15 other studies available for edrophonium and Muscle Disorders

ArticleYear
Myasthenia due to carnitine treatment.
    Journal of the neurological sciences, 1980, Volume: 46, Issue:3

    Topics: Adult; Carnitine; Edrophonium; Electrophysiology; Humans; Middle Aged; Muscular Diseases; Neural Con

1980
[Electromyographic and histopathological study of the Lambert-Eaton myasthenia syndrome. Apropos of a case].
    Electrodiagnostic-Therapie, 1980, Volume: 17, Issue:1

    Topics: Action Potentials; Edrophonium; Electric Stimulation; Electromyography; Humans; Male; Middle Aged; M

1980
Myasthenic decrement and myasthenic myopathy. A study on the effects of thymectomy.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:6

    Topics: Acetylcholine; Action Potentials; Adenosine Triphosphatases; Adrenocorticotropic Hormone; Edrophoniu

1975
Pseudo one-and-a-half syndrome with ocular myasthenia.
    Neurology, 1989, Volume: 39, Issue:11

    Topics: Aged; Blepharoptosis; Edrophonium; Humans; Male; Muscular Diseases; Oculomotor Muscles; Ophthalmople

1989
Myasthenic crisis after intravenous administration of iodinated contrast agent.
    Neurology, 1985, Volume: 35, Issue:8

    Topics: Aged; Apnea; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Edrophonium; Female; Humans; Middle

1985
Myasthenic syndrome in a dog.
    Electroencephalography and clinical neurophysiology, 1971, Volume: 30, Issue:3

    Topics: Animals; Dogs; Edrophonium; Extremities; Muscular Diseases; Pyridostigmine Bromide

1971
A myopathy associated with lipid storage.
    Journal of the neurological sciences, 1972, Volume: 16, Issue:2

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Chromatography, Thin Layer; C

1972
A reevaluation of edrophonium chloride (Tensilon) tonography in the diagnosis of myasthenia gravis. With observations on some other defects of neuromuscular transmission.
    Neurology, 1971, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Child; Edrophonium; Electromyography; Female; Humans;

1971
Peripheral neuropathy with myokymia, sustained muscular contraction, and continuous motor unit activity.
    Neurology, 1972, Volume: 22, Issue:2

    Topics: Action Potentials; Adult; Calcium; Decamethonium Compounds; Demyelinating Diseases; Edrophonium; Ele

1972
Alterations in reactivity to acetylcholine in myasthenia gravis and carcinomatous myopathy.
    Annals of the New York Academy of Sciences, 1966, Jan-26, Volume: 135, Issue:1

    Topics: Acetylcholine; Aged; Biphenyl Compounds; Cholinesterase Inhibitors; Edrophonium; Female; Ganglionic

1966
A myasthenic syndrome in childhood leukemia.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:5

    Topics: Blepharoptosis; Bone Marrow Examination; Child; Edrophonium; Electric Stimulation; Electromyography;

1974
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F

1974
The Eaton-Lambert syndrome in ocular myasthenia gravis.
    Archives of neurology, 1974, Volume: 31, Issue:3

    Topics: Bronchial Neoplasms; Carcinoma; Diagnosis, Differential; Edrophonium; Electric Stimulation; Electrom

1974
Syndromes simulating myasthenia gravis.
    Annals of the New York Academy of Sciences, 1966, Jan-26, Volume: 135, Issue:1

    Topics: Adult; Aged; Brain Diseases; Brain Stem; Diagnosis, Differential; Edrophonium; Extrapyramidal Tracts

1966
The myasthenic syndrome associated with small cell carcinoma of the lung (Eaton-Lambert syndrome.
    Neurology, 1968, Volume: 18, Issue:8

    Topics: Action Potentials; Aged; Blepharoptosis; Carcinoma; Edrophonium; Electric Stimulation; Electromyogra

1968