edrophonium has been researched along with Muscle Contraction in 108 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Strong esophageal contractions and not a decreased blood flow in the esophageal wall seem to be the cause of chest pain provoked by intravenous edrophonium chloride." | 7.69 | The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility. ( Gustafsson, U; Tibbling, L, 1997) |
| "Strong esophageal contractions and not a decreased blood flow in the esophageal wall seem to be the cause of chest pain provoked by intravenous edrophonium chloride." | 3.69 | The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility. ( Gustafsson, U; Tibbling, L, 1997) |
| ") dose of edrophonium to produce a potentiation of muscle contraction dependent on repetitive discharges in the soleus motor nerve terminals." | 3.67 | Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission. ( Hall, ED; Von Voigtlander, PF, 1987) |
| "08 mg/kg), 36 surgical patients undergoing barbiturate/halothane anesthesia were given edrophonium 0." | 3.67 | [Antagonism of an intubation dose of vecuronium]. ( Baar, H; Lazarus, G; Sold, M, 1987) |
| "Orbicularis oculi fatiguability following maximal voluntary contraction and its recovery after administration of Tensilon (edrophonium chloride) were studied in 13 patients with myasthenia gravis (MG) and 8 normal controls." | 3.66 | Electromyographic assessment of fatiguability and recovery of orbicularis oculi in myasthenia gravis. ( Ayyar, DR; Kimura, I; Kogure, K; Sato, G, 1983) |
| "A close correlation has been shown to exist between the in vitro anticholinesterase potencies of ambenonium, neostigmine, methoxyambenonium and edrophonium chloride and their abilities to increase muscle contractions produced by close-arterial injections of acetylcholine." | 3.64 | Facilitation of neuromuscular transmission by anticholinesterase drugs. ( BLABER, LC, 1963) |
| "When edrophonium was used, no cases of recurarization were observed." | 2.84 | Effects of neostigmine or edrophonium on force of contraction when administered at a train-of-four ratio of 0.9 in anesthetized dogs. ( Campoy, L; Gleed, RD; Martin-Flores, M; Romano, M; Sakai, DM; Tseng, CT, 2017) |
| "Neostigmine has a similar, although longer, effect." | 2.69 | Effect of edrophonium and neostigmine on the pharmacokinetics and neuromuscular effects of mivacurium. ( Brown, R; Fisher, DM; Fogarty, D; Kirkegaard-Nielsen, H; Sharma, ML; Szenohradszky, J, 2000) |
| "The dose-response relationship for edrophonium during antagonism of vecuronium-induced neuromuscular blockade was studied in two groups of adult patients of mean (SD) age 35 (10." | 2.68 | Dose-responses for edrophonium during antagonism of vecuronium block in young and older adult patients. ( Maddineni, VR; McCarthy, GJ; McCoy, EP; Mirakhur, RK, 1995) |
| "Edrophonium 0." | 2.68 | Antagonism of mivacurium block with edrophonium from various degrees of spontaneous recovery. ( Connolly, FM; Kumar, N; Loan, PB; McCoy, EP; Mirakhur, RK; Symington, M, 1995) |
| "Edrophonium was found to be less effective than neostigmine at reversing rocuronium bromide-induced TOF fade." | 2.67 | Dose-response relationships for edrophonium and neostigmine antagonism of rocuronium bromide (ORG 9426)-induced neuromuscular blockade. ( Abdulatif, M; al-Ghamdi, A; Naguib, M, 1993) |
| "We have studied the dose-response relationships for neostigmine and edrophonium during antagonism of neuromuscular block induced by mivacurium chloride." | 2.67 | Dose-response relationships for edrophonium and neostigmine antagonism of mivacurium-induced neuromuscular block. ( Abdulatif, M; al-Ghamdi, A; Hamo, I; Naguib, M; Nouheid, R, 1993) |
| "Seventeen patients with end stage chronic renal failure and 18 patients with normal renal function were anaesthetized with 0." | 2.67 | Neuromuscular block with doxacurium (BW A938U) in patients with normal or absent renal function. ( Cashman, JN; Jones, RM; Luke, JJ, 1990) |
| "Edrophonium 1." | 2.66 | Train-of-four ratio after antagonism of atracurium with edrophonium: influence of different priming doses of edrophonium. ( Naguib, M, 1989) |
| "Edrophonium 1." | 2.66 | Priming with anti-cholinesterases--the effect of different priming doses of edrophonium. ( Abdulatif, M; Naguib, M, 1988) |
| "To determine the potencies of neostigmine, pyridostigmine, and edrophonium in reversing pancuronium and d-tubocurarine blockade, dose-response curves were established for first twitch height recovery and train-of-four ratio." | 2.66 | Dose-response curves for edrophonium, neostigmine, and pyridostigmine after pancuronium and d-tubocurarine. ( Antzaka, C; Bevan, DR; Donati, F; McCarroll, SM; McCready, D, 1987) |
| "Bisacodyl was superior to edrophonium as a stimulant for inducing high-amplitude-propagating contractions." | 1.30 | Bisacodyl and high-amplitude-propagating colonic contractions in children. ( Di Lorenzo, C; Flores, AF; Hamid, SA; Hyman, PE; Reddy, SN, 1998) |
| "(3) Tetrodotoxin (TTX) was tested on the anti-ChE drugs-induced responses." | 1.30 | Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs. ( Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A, 1998) |
| " administration decreased at high doses of each drug and the dose-response curves were biphasic." | 1.29 | Pharmacodynamic analysis of contractile potentiation by cholinesterase inhibitors in rats. ( Iga, T; Sawada, Y; Yamamoto, K, 1996) |
| " Birds were randomly assigned to 4 groups, and atracurium was administered at dosage of 0." | 1.28 | Neuromuscular and cardiovascular effects of atracurium in isoflurane-anesthetized chickens. ( Ilkiw, JE; Nicholson, A, 1992) |
| "The time to safe return of neuromuscular function after atracurium 0." | 1.28 | Atracurium recovery: prediction of safe reversal times with edrophonium. ( Adams, AP; Cashman, JN; Jones, RM, 1989) |
| "Atracurium did not cause cardiovascular changes." | 1.27 | Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane. ( Arpin, D; Hildebrand, SV, 1988) |
| "Pancuronium was infused at a constant rate to produce a stable 50% depression of single twitch tension." | 1.27 | Edrophonium antagonizes combined lidocaine-pancuronium and verapamil-pancuronium neuromuscular blockade in cats. ( Carpenter, RL; Mulroy, MF, 1986) |
| "Edrophonium was more potent than neostigmine in reversing the combined neuromuscular blockade produced by the muscle relaxants with and without verapamil." | 1.27 | Interaction of verapamil with gallamine and pancuronium and reversal of combined neuromuscular blockade with neostigmine and edrophonium. ( Wali, FA, 1986) |
| "Edrophonium was about 12 times less potent than neostigmine in antagonizing Org NC 45." | 1.26 | Some actions of Org NC 45 and of edrophonium in the anaesthetized cat and in man. ( Baird, WL; Bowman, WC; Kerr, WJ, 1982) |
| "Edrophonium (0." | 1.26 | Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia. ( Cronnelly, R; Miller, RD; Morris, RB, 1982) |
| "Edrophonium was more effective in alleviating decrement in the platysma than in the ADP." | 1.26 | Electrical and mechanical responses in the platysma and in the adductor pollicis muscle: in patients with myasthenia gravis. ( Krarup, C, 1977) |
| "In two subjects with paramyotonia congenita the isometric torque generated by the abductor digiti minimi and the surface EMG recorded over ADM decreased during prolonged or repetitive contractions, whether these were voluntarily or electrically induced." | 1.25 | Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita. ( Burke, D; Lethlean, AK; Skuse, NF, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 75 (69.44) | 18.7374 |
| 1990's | 27 (25.00) | 18.2507 |
| 2000's | 5 (4.63) | 29.6817 |
| 2010's | 1 (0.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romano, M | 1 |
| Martin-Flores, M | 1 |
| Sakai, DM | 1 |
| Tseng, CT | 1 |
| Campoy, L | 1 |
| Gleed, RD | 1 |
| Korsapati, H | 2 |
| Bhargava, V | 2 |
| Mittal, RK | 3 |
| Babaei, A | 1 |
| Dohil, R | 1 |
| Quin, A | 1 |
| BLABER, LC | 1 |
| Shibata, O | 2 |
| Saito, M | 1 |
| Yoshimura, M | 1 |
| Yamaguchi, M | 1 |
| Makita, T | 2 |
| Sumikawa, K | 2 |
| Flattum, RF | 1 |
| Friedman, S | 1 |
| Larsen, JR | 1 |
| Edge, ND | 1 |
| Harper, NJ | 1 |
| Bradshaw, EG | 1 |
| Healy, TE | 1 |
| Baird, WL | 4 |
| Bowman, WC | 1 |
| Kerr, WJ | 2 |
| Hall, ED | 3 |
| Donati, F | 4 |
| Ferguson, A | 1 |
| Bevan, DR | 5 |
| Meakin, G | 1 |
| Sweet, PT | 1 |
| Bevan, JC | 1 |
| Jones, RM | 4 |
| Pearce, AC | 1 |
| Williams, JP | 1 |
| Hildebrand, SV | 2 |
| Howitt, GA | 1 |
| Kimura, I | 1 |
| Ayyar, DR | 1 |
| Sato, G | 1 |
| Kogure, K | 1 |
| Benjamin, SB | 1 |
| Richter, JE | 1 |
| Cordova, CM | 1 |
| Knuff, TE | 1 |
| Castell, DO | 1 |
| Klein, C | 1 |
| Hopkins, J | 1 |
| Beck, E | 1 |
| Burton, B | 1 |
| Cronnelly, R | 1 |
| Morris, RB | 1 |
| Miller, RD | 1 |
| Trojan, DA | 1 |
| Cashman, NR | 1 |
| McCarthy, GJ | 1 |
| Mirakhur, RK | 4 |
| Maddineni, VR | 1 |
| McCoy, EP | 2 |
| Connolly, FM | 1 |
| Loan, PB | 1 |
| Symington, M | 1 |
| Kumar, N | 1 |
| Baurain, MJ | 1 |
| Dernovoi, BS | 1 |
| d'Hollander, AA | 1 |
| Hennart, DA | 1 |
| Cantraine, FR | 1 |
| Abdulatif, M | 6 |
| Clutton, RE | 1 |
| Salib, YM | 1 |
| Valdrighi, JB | 1 |
| Fleming, NW | 1 |
| Smith, BK | 1 |
| Baker, GL | 1 |
| White, DA | 1 |
| Naguib, M | 6 |
| al-Ghamdi, A | 2 |
| Hamo, I | 1 |
| Nouheid, R | 1 |
| Shorten, GD | 1 |
| Ali, HA | 1 |
| Yamamoto, K | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
| Gustafsson, U | 1 |
| Tibbling, L | 2 |
| Matsukawa, S | 1 |
| Hashimoto, Y | 1 |
| Kato, M | 1 |
| Hoshi, K | 1 |
| Satoh, D | 1 |
| Horinouchi, T | 1 |
| Satoh, S | 1 |
| Saishu, T | 1 |
| Brandom, BW | 1 |
| Woelfel, SK | 1 |
| Ference, A | 1 |
| Dayal, B | 1 |
| Cook, DR | 1 |
| Kerls, S | 1 |
| Hamid, SA | 1 |
| Di Lorenzo, C | 1 |
| Reddy, SN | 1 |
| Flores, AF | 1 |
| Hyman, PE | 1 |
| Balaban, DH | 1 |
| Yamamoto, Y | 1 |
| Liu, J | 1 |
| Pehlivanov, N | 1 |
| Wisniewski, R | 1 |
| DeSilvey, D | 1 |
| Narimatsu, E | 1 |
| Nakayama, Y | 1 |
| Sumita, S | 1 |
| Iwasaki, H | 1 |
| Fujimura, N | 1 |
| Satoh, K | 1 |
| Namiki, A | 1 |
| Tsuda, A | 1 |
| Iwanaga, S | 1 |
| Hara, T | 1 |
| Shibata, S | 1 |
| Szenohradszky, J | 1 |
| Fogarty, D | 1 |
| Kirkegaard-Nielsen, H | 1 |
| Brown, R | 1 |
| Sharma, ML | 1 |
| Fisher, DM | 1 |
| Yossepowitch, O | 1 |
| Gillon, G | 1 |
| Baniel, J | 1 |
| Engelstein, D | 1 |
| Livne, PM | 1 |
| Barber, HE | 3 |
| Calvey, TN | 3 |
| Muir, KT | 3 |
| Taylor, K | 2 |
| Pinson, RA | 1 |
| Dretchen, KL | 2 |
| Kruger, GO | 1 |
| Krarup, C | 1 |
| Lee, C | 2 |
| Yang, E | 1 |
| Katz, RL | 3 |
| Riker, WF | 6 |
| Baker, T | 2 |
| Harborne, AJ | 1 |
| Smith, ME | 1 |
| Jones, R | 1 |
| Drakontides, AB | 1 |
| Ryan, JP | 1 |
| Duffy, KR | 1 |
| Ferko, AP | 3 |
| Mumenthaler, M | 1 |
| Lütschg, J | 1 |
| Sugai, N | 3 |
| Payne, JP | 5 |
| Brown, JC | 2 |
| Charlton, JE | 1 |
| White, DJ | 1 |
| Lowndes, HE | 1 |
| Schwartz, MS | 1 |
| Stålberg, E | 2 |
| Raines, A | 1 |
| Hughes, R | 3 |
| Chen, D | 1 |
| Nagel, EL | 1 |
| Okamoto, M | 3 |
| Walewski, JL | 1 |
| Artusio, JF | 2 |
| Jensen, FS | 1 |
| Viby-Mogensen, J | 2 |
| Nicholson, A | 1 |
| Ilkiw, JE | 1 |
| Kopman, AF | 1 |
| Cashman, JN | 2 |
| Luke, JJ | 1 |
| Szalados, JE | 1 |
| Adams, AP | 1 |
| Von Voigtlander, PF | 1 |
| Engbaek, J | 1 |
| Ording, H | 1 |
| Ostergaard, D | 1 |
| Caldwell, JE | 2 |
| Robertson, EN | 2 |
| Gibson, FM | 2 |
| Lavery, GG | 2 |
| Astley, BA | 2 |
| Sold, M | 1 |
| Lazarus, G | 1 |
| Baar, H | 1 |
| Albuquerque, EX | 1 |
| Aracava, Y | 1 |
| Cintra, WM | 1 |
| Brossi, A | 1 |
| Schönenberger, B | 1 |
| Deshpande, SS | 1 |
| Mier-Jedrzejowicz, AK | 1 |
| Brophy, C | 1 |
| Green, M | 1 |
| Arpin, D | 1 |
| McCarroll, SM | 1 |
| Antzaka, C | 1 |
| McCready, D | 1 |
| Wali, FA | 2 |
| McAteer, E | 1 |
| Suer, AH | 1 |
| Albera, R | 1 |
| Morra, B | 1 |
| Lucisano, S | 1 |
| Bernini, A | 1 |
| Lacilla, M | 1 |
| Ask, P | 1 |
| Pope, CE | 1 |
| Casson, WR | 1 |
| Carpenter, RL | 1 |
| Mulroy, MF | 1 |
| Freeman, SE | 1 |
| Turner, RJ | 1 |
| Blum, K | 1 |
| Welch, LK | 1 |
| Appenzeller, O | 1 |
| Bicknell, JM | 1 |
| Ellis, KO | 1 |
| Carpenter, JF | 1 |
| Bunn, PA | 1 |
| Lundberg, PO | 1 |
| Thiele, B | 1 |
| Patten, BM | 1 |
| Oliver, KL | 1 |
| Engel, WK | 1 |
| Walsh, JC | 1 |
| Pleuvry, BJ | 1 |
| Hunter, AR | 1 |
| Burke, D | 1 |
| Skuse, NF | 1 |
| Lethlean, AK | 1 |
| Turner, P | 1 |
| Variava, DM | 1 |
| Capetola, R | 1 |
| Calesnick, B | 2 |
| Tenser, RB | 1 |
| Corbett, JJ | 1 |
| Tyrrell, MF | 1 |
| Ireson, JD | 1 |
| Ford, R | 1 |
| Loveday, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Can we Antagonize Mivacurium With Neostigmine[NCT03019835] | 80 participants (Actual) | Interventional | 2016-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for edrophonium and Muscle Contraction
| Article | Year |
|---|---|
Structure-activity relationship of reversible cholinesterase inhibitors: activation, channel blockade and stereospecificity of the nicotinic acetylcholine receptor-ion channel complex.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Edrophonium; Muscl | 1988 |
22 trials available for edrophonium and Muscle Contraction
| Article | Year |
|---|---|
Effects of neostigmine or edrophonium on force of contraction when administered at a train-of-four ratio of 0.9 in anesthetized dogs.
Topics: Anesthesia, General; Animals; Cross-Over Studies; Dogs; Edrophonium; Muscle Contraction; Neostigmine | 2017 |
Antagonism of alcuronium with edrophonium or neostigmine.
Topics: Alcuronium; Edrophonium; Humans; Muscle Contraction; Neostigmine; Neuromuscular Junction; Ophthalmol | 1984 |
Recovery characteristics following antagonism of atracurium with neostigmine or edrophonium.
Topics: Adult; Atracurium; Edrophonium; Humans; Isoquinolines; Muscle Contraction; Neostigmine; Neuromuscula | 1984 |
Dose-responses for edrophonium during antagonism of vecuronium block in young and older adult patients.
Topics: Adolescent; Adult; Aged; Aging; Dose-Response Relationship, Drug; Edrophonium; Humans; Kinetics; Mid | 1995 |
Antagonism of mivacurium block with edrophonium from various degrees of spontaneous recovery.
Topics: Adult; Anesthesia Recovery Period; Edrophonium; Electric Stimulation; Humans; Isoquinolines; Mivacur | 1995 |
Low and high frequency stimulation tests to characterize the effects of edrophonium on vecuronium-induced neuromuscular block.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Edrophonium; Humans; Middle Aged; Muscle Contra | 1995 |
Recovery characteristics after early administration of anticholinesterases during intense mivacurium-induced neuromuscular block.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Cholinesterase Inhibitors; Edrophonium; Electric Stim | 1995 |
Edrophonium for the antagonism of neuromuscular blockade in dogs.
Topics: Anesthesia, Intravenous; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Edrophonium; Ele | 1994 |
Dose-response relationships for edrophonium and neostigmine antagonism of rocuronium bromide (ORG 9426)-induced neuromuscular blockade.
Topics: Adult; Androstanols; Dose-Response Relationship, Drug; Drug Interactions; Edrophonium; Electric Stim | 1993 |
Dose-response relationships for edrophonium and neostigmine antagonism of mivacurium-induced neuromuscular block.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Edrophonium; Female; Humans; Isoquinolines; Mal | 1993 |
Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography.
Topics: Adolescent; Adult; Aged; Chest Pain; Deglutition; Edrophonium; Esophageal Motility Disorders; Esopha | 1999 |
Effect of edrophonium and neostigmine on the pharmacokinetics and neuromuscular effects of mivacurium.
Topics: Adult; Aged; Aging; Cholinesterase Inhibitors; Drug Interactions; Edrophonium; Female; Humans; Isoqu | 2000 |
The skeletal muscle response to edrophonium during neuromuscular blockade by tubocurarine in anaesthetized man.
Topics: Aged; Clinical Trials as Topic; Edrophonium; Electric Stimulation; Humans; Male; Middle Aged; Muscle | 1975 |
Edrophonium priming alters the course of neuromuscular recovery from a pipecuronium neuromuscular blockade.
Topics: Adult; Androstane-3,17-diol; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intrave | 1991 |
Neuromuscular block with doxacurium (BW A938U) in patients with normal or absent renal function.
Topics: Adult; Aged; Anesthesia, General; Drug Evaluation; Edrophonium; Female; Hemodynamics; Humans; Isoqui | 1990 |
Train-of-four ratio after antagonism of atracurium with edrophonium: influence of different priming doses of edrophonium.
Topics: Adult; Anesthesia Recovery Period; Atracurium; Clinical Trials as Topic; Edrophonium; Electric Stimu | 1989 |
Antagonism of profound neuromuscular blockade induced by vecuronium or atracurium. Comparison of neostigmine with edrophonium.
Topics: Adult; Atracurium; Edrophonium; Humans; Middle Aged; Muscle Contraction; Neostigmine; Neuromuscular | 1986 |
Antagonism of vecuronium-induced neuromuscular blockade with edrophonium or neostigmine.
Topics: Adult; Edrophonium; Humans; Muscle Contraction; Neostigmine; Time Factors; Vecuronium Bromide | 1987 |
Antagonism of vecuronium and atracurium: comparison of neostigmine and edrophonium administered at 5% twitch height recovery.
Topics: Adult; Atracurium; Edrophonium; Humans; Muscle Contraction; Neostigmine; Time Factors; Vecuronium Br | 1987 |
Priming with anti-cholinesterases--the effect of different combinations of anti-cholinesterases and different priming intervals.
Topics: Adult; Anesthesia Recovery Period; Atracurium; Drug Administration Schedule; Edrophonium; Female; Hu | 1988 |
Priming with anti-cholinesterases--the effect of different priming doses of edrophonium.
Topics: Adult; Anesthesia Recovery Period; Atracurium; Dose-Response Relationship, Drug; Drug Administration | 1988 |
Dose-response curves for edrophonium, neostigmine, and pyridostigmine after pancuronium and d-tubocurarine.
Topics: Adult; Dose-Response Relationship, Drug; Edrophonium; Female; Humans; Male; Middle Aged; Muscle Cont | 1987 |
85 other studies available for edrophonium and Muscle Contraction
| Article | Year |
|---|---|
Reversal of asynchrony between circular and longitudinal muscle contraction in nutcracker esophagus by atropine.
Topics: Adult; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Edrophonium; Esophagea | 2008 |
Dysfunction of the longitudinal muscles of the oesophagus in eosinophilic oesophagitis.
Topics: Adult; Cholinesterase Inhibitors; Edrophonium; Eosinophilia; Esophagitis; Esophagus; Female; Humans; | 2009 |
Facilitation of neuromuscular transmission by anticholinesterase drugs.
Topics: Acetylcholine; Ambenonium Chloride; Cholinesterase Inhibitors; Cholinesterases; Edrophonium; Electri | 1963 |
Interactions of edrophonium with neostigmine in the rat trachea.
Topics: Animals; Drug Interactions; Edrophonium; In Vitro Techniques; Inosine Triphosphate; Male; Muscle Con | 2003 |
The effects of d-tubocurare chloride on nervous activity and muscular contraction in the house cricket Acheta domesticus (L.).
Topics: Animals; Barbiturates; Central Nervous System; Curare; Edrophonium; Electrophysiology; Insecta; Musc | 1967 |
pPy: a measure of potentiating activity.
Topics: Acetylcholine; Animals; Anura; Cholinesterase Inhibitors; Curare; Edrophonium; Isoflurophate; Muscle | 1967 |
Some actions of Org NC 45 and of edrophonium in the anaesthetized cat and in man.
Topics: Adult; Aged; Anesthesia, General; Animals; Cats; Edrophonium; Female; Humans; Male; Middle Aged; Mus | 1982 |
Glucocorticoid modification of the responsiveness of a fast (type 2) neuromuscular system to edrophonium and d-tubocurarine.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Edrophonium; Female; Male; Muscle Contraction; Neur | 1980 |
Twitch depression and train-of-four ratio after antagonism of pancuronium with edrophonium, neostigmine, or pyridostigmine.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Edrophonium; Electric Stimulation; Humans; Middle Aged | 1983 |
Neostigmine and edrophonium as antagonists of pancuronium in infants and children.
Topics: Anesthesia; Child; Child, Preschool; Edrophonium; Humans; Infant; Infant, Newborn; Muscle Contractio | 1983 |
Antagonism of pancuronium neuromuscular blockade in halothane-anesthetized ponies using neostigmine and edrophonium.
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Digestive System; Edrophonium; | 1984 |
Electromyographic assessment of fatiguability and recovery of orbicularis oculi in myasthenia gravis.
Topics: Adolescent; Adult; Aged; Edrophonium; Electromyography; Facial Muscles; Female; Humans; Middle Aged; | 1983 |
Reversal of atracurium with edrophonium.
Topics: Adult; Atracurium; Edrophonium; Electric Stimulation; Humans; Isoquinolines; Middle Aged; Muscle Con | 1983 |
Prospective manometric evaluation with pharmacologic provocation of patients with suspected esophageal motility dysfunction.
Topics: Adult; Aged; Bethanechol Compounds; Deglutition Disorders; Edrophonium; Esophageal Achalasia; Esopha | 1983 |
Mechanical responses to peroneal nerve stimulation in halothane-anesthetized horses in the absence of neuromuscular blockade and during partial nondepolarizing blockade.
Topics: Anesthesia; Animals; Cats; Edrophonium; Electric Stimulation; Gallamine Triethiodide; Halothane; Hor | 1983 |
Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Dose-Response Relationship, Dru | 1982 |
Anticholinesterases in post-poliomyelitis syndrome.
Topics: Edrophonium; Electromyography; Fatigue; Humans; Muscle Contraction; Neuromuscular Junction; Postpoli | 1995 |
Edrophonium antagonism of vecuronium at varying degrees of fourth twitch recovery.
Topics: Adult; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Edrophonium; Female; Humans; Injec | 1993 |
Effects of cholinesterase inhibitors on the neuromuscular blocking action of suxamethonium.
Topics: Animals; Cholinesterase Inhibitors; Drug Interactions; Edrophonium; Hindlimb; Male; Muscle Contracti | 1994 |
Atracurium after an anticholinesterase. Does prior reversal with edrophonium or neostigmine influence the response to atracurium?
Topics: Adult; Atracurium; Edrophonium; Female; Humans; Male; Muscle Contraction; Neostigmine; Neuromuscular | 1993 |
Pharmacodynamic analysis of contractile potentiation by cholinesterase inhibitors in rats.
Topics: Ambenonium Chloride; Animals; Cattle; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; E | 1996 |
The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility.
Topics: Adult; Aged; Chest Pain; Cholinesterase Inhibitors; Edrophonium; Esophageal Motility Disorders; Esop | 1997 |
An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication.
Topics: Adult; Cholinesterase Inhibitors; Edrophonium; Electric Stimulation; Female; Humans; Insecticides; M | 1997 |
Effects of cisatracurium in children during halothane-nitrous oxide anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Antidotes; Atracurium; | 1998 |
Bisacodyl and high-amplitude-propagating colonic contractions in children.
Topics: Adolescent; Bisacodyl; Cecum; Child; Child, Preschool; Colon; Edrophonium; Female; Humans; Infant; I | 1998 |
Sepsis attenuates the intensity of the neuromuscular blocking effect of d-tubocurarine and the antagonistic actions of neostigmine and edrophonium accompanying depression of muscle contractility of the diaphragm.
Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Dose-Response Relationship, Drug; Edrophonium; In Vit | 1999 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodi | 1998 |
The effect of cholinergic enhancement during filling cystometry: can edrophonium chloride be used as a provocative test for overactive bladder?
Topics: Adult; Aged; Cholinergic Fibers; Cholinesterase Inhibitors; Edrophonium; Female; Humans; Male; Middl | 2001 |
The effect of edrophonium on erythrocyte acetylcholinesterase and neuromuscular function in the rat.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Edrophonium; Erythrocytes; Male; Muscle Co | 1976 |
An investigation of the effects of a pyridyl and a piperidyl 1, 3-dioxolane derivative on neuromuscular transmission.
Topics: Animals; Cats; Chick Embryo; Diaphragm; Dioxolanes; Dioxoles; Edrophonium; In Vitro Techniques; Musc | 1976 |
Electrical and mechanical responses in the platysma and in the adductor pollicis muscle: in patients with myasthenia gravis.
Topics: Adult; Aged; Edrophonium; Evoked Potentials; Female; Humans; Middle Aged; Muscle Contraction; Muscle | 1977 |
Interactions of neuromuscular effects of edrophonium, alpha-bungarotoxin and beta-bungarotoxin.
Topics: Animals; Bungarotoxins; Chickens; Denervation; Drug Interactions; Edrophonium; Female; Models, Neuro | 1978 |
Glucocorticoid effects on the edrophonium responsiveness of normal and degenerating mammalian motor nerve terminals.
Topics: Animals; Axons; Cats; Edrophonium; Evoked Potentials; Muscle Contraction; Nerve Degeneration; Neurom | 1977 |
The relationship between the pharmacokinetics, cholinesterase inhibition and facilitation of twitch tension of the quaternary ammonium anticholinesterase drugs, neostigmine, pyridostigmine, edrophonium and 3-hydroxyphenyltrimethylammonium.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Edrophonium; Erythrocytes; Half-Life; Kine | 1979 |
The effect of hydrolytic enzymes on the acetylcholine sensitivity of the skeletal muscle cell membrane.
Topics: Acetylcholine; Animals; Bungarotoxins; Carbachol; Drug Interactions; Edrophonium; Hydrolases; In Vit | 1978 |
Functional, pharmacologic, and ultrastructural correlates in degenerating rat motor nerve terminals.
Topics: Animals; Edrophonium; Evoked Potentials; Male; Motor Neurons; Muscle Contraction; Nerve Degeneration | 1978 |
LES pressure response to pentagastrin: effect of cholinergic augmentation and inhibition.
Topics: Acetylcholine; Animals; Atropine; Edrophonium; Esophagogastric Junction; Female; Male; Muscle Contra | 1978 |
The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Interactions; Ed | 1976 |
[Pseudoparalytic myasthenia gravis. Diagnostic and therapeutic aspects in 60 separate cases].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Diagnosis, Differential; Edrophonium; | 1976 |
A regional technique for the study of sensitivity to curare in human muscle.
Topics: Action Potentials; Adult; Aged; Edrophonium; Electric Stimulation; Evoked Potentials; Female; Humans | 1975 |
Motor nerve terminal response to edrophonium in delayed DFP neuropathy.
Topics: Action Potentials; Animals; Cats; Drug Synergism; Edrophonium; Female; Isoflurophate; Male; Motor Ne | 1975 |
Proceedings: The relation between the plasma concentration of edrophonium, inhibition of erythrocyte acetylcholinesterase, and the facilitation of neuromuscular function in the rat.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Edrophonium; Erythrocytes; In Vitro Techni | 1975 |
Myasthenia gravis with features of the myasthenic syndrome. An investigation with electrophysiologic methods including single-fiber electromyography.
Topics: Action Potentials; Drug Therapy, Combination; Edrophonium; Electric Stimulation; Electromyography; F | 1975 |
Neuroexcitatory and depressant effects of penicillin at the cat soleus neuromuscular junction.
Topics: Action Potentials; Animals; Cats; Drug Interactions; Edrophonium; Injections, Intra-Arterial; Inject | 1975 |
The skeletal muscle response to the repeated administration of suxamethonium and its interaction with edrophonium in anaesthetised man.
Topics: Aged; Drug Administration Schedule; Drug Interactions; Edrophonium; Female; Humans; Injections, Intr | 1975 |
Spontaneous recovery of the thumb twitch from neuromuscular block by suxamethonium in anaesthetized man.
Topics: Adult; Dose-Response Relationship, Drug; Edrophonium; Electric Stimulation; Humans; Muscle Contracti | 1976 |
Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Cholinesterase Inhibitors; Curare; Dose-Response | 1992 |
Reaction to succinylcholine in two patients segregating for the plasma cholinesterase allele Ek.
Topics: Alleles; Cholinesterases; Edrophonium; Electric Stimulation; Female; Genotype; Humans; Injections, I | 1992 |
Neuromuscular and cardiovascular effects of atracurium in isoflurane-anesthetized chickens.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Animals; Atracurium; Blood Pressure; Chickens; D | 1992 |
Tactile evaluation of train-of-four count as an indicator of reliability of antagonism of vecuronium- or atracurium-induced neuromuscular blockade.
Topics: Adult; Aged; Atracurium; Edrophonium; Humans; Middle Aged; Muscle Contraction; Muscles; Neuromuscula | 1991 |
The interactions of ouabain with post-tetanic and facilitatory drug potentiations at cat soleus neuromuscular junctions in vivo.
Topics: Animals; Calcium; Cats; Cobalt; Edrophonium; Electric Stimulation; Evoked Potentials; Magnesium; Man | 1990 |
Edrophonium priming for antagonism of atracurium neuromuscular blockade.
Topics: Adult; Anesthesia Recovery Period; Atracurium; Edrophonium; Evoked Potentials; Female; Humans; Male; | 1990 |
Atracurium recovery: prediction of safe reversal times with edrophonium.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, General; Atracurium; Edrophonium; Female; | 1989 |
Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission.
Topics: Animals; Cats; Edrophonium; Female; Hemicholinium 3; In Vitro Techniques; Lethal Dose 50; Male; Mice | 1987 |
Edrophonium and neostigmine for reversal of the neuromuscular blocking effect of vecuronium.
Topics: Adult; Edrophonium; Female; Humans; Laparoscopy; Muscle Contraction; Neostigmine; Neuroleptanalgesia | 1985 |
Electrical and mechanical responses after neuromuscular blockade with vecuronium, and subsequent antagonism with neostigmine or edrophonium.
Topics: Adult; Aged; Edrophonium; Electromyography; Humans; Middle Aged; Muscle Contraction; Neostigmine; Ne | 1987 |
[Antagonism of an intubation dose of vecuronium].
Topics: Anesthesia; Edrophonium; Halothane; Humans; Intubation; Muscle Contraction; Muscle Relaxation; Neost | 1987 |
A comparison of edrophonium and neostigmine for the antagonism of atracurium-induced neuromuscular block.
Topics: Adult; Atracurium; Edrophonium; Humans; Isoquinolines; Middle Aged; Muscle Contraction; Neostigmine; | 1985 |
Respiratory muscle function in myasthenia gravis.
Topics: Adult; Diaphragm; Edrophonium; Female; Humans; Middle Aged; Mouth; Muscle Contraction; Myasthenia Gr | 1988 |
Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane.
Topics: Anesthesia, Inhalation; Animals; Atracurium; Blood Pressure; Edrophonium; Halothane; Heart Rate; Hor | 1988 |
Interaction of verapamil with atracurium and reversal of combined neuromuscular blockade with edrophonium and neostigmine.
Topics: Animals; Atracurium; Edrophonium; In Vitro Techniques; Muscle Contraction; Neostigmine; Neuromuscula | 1987 |
Dynamic aspects of stapedial reflex in myasthenia gravis.
Topics: Adolescent; Adult; Aged; Ear Ossicles; Edrophonium; Female; Humans; Male; Middle Aged; Muscle Contra | 1987 |
Electromyography of human oesophageal smooth muscle.
Topics: Animals; Atropine; Deglutition; Edrophonium; Electromyography; Esophageal Diseases; Esophagogastric | 1986 |
Profound atracurium induced neuromuscular blockade. A comparison of evoked reversal with edrophonium or neostigmine.
Topics: Adult; Atracurium; Edrophonium; Humans; Isoquinolines; Muscle Contraction; Neostigmine; Neuromuscula | 1986 |
Edrophonium antagonizes combined lidocaine-pancuronium and verapamil-pancuronium neuromuscular blockade in cats.
Topics: Animals; Cats; Edrophonium; Infusions, Intravenous; Infusions, Parenteral; Injections, Intravenous; | 1986 |
Antagonism of atracurium-induced neuromuscular blockade by neostigmine or edrophonium.
Topics: Atracurium; Edrophonium; Humans; Muscle Contraction; Neostigmine; Neuromuscular Blocking Agents; Tim | 1986 |
Interaction of verapamil with gallamine and pancuronium and reversal of combined neuromuscular blockade with neostigmine and edrophonium.
Topics: Animals; Chickens; Drug Interactions; Edrophonium; Gallamine Triethiodide; In Vitro Techniques; Musc | 1986 |
Facilitatory drug action on the isolated phrenic nerve-diaphragm preparation of the rat.
Topics: Acetylcholine; Acridines; Aniline Compounds; Animals; Calcium; Denervation; Diaphragm; Edrophonium; | 1970 |
The effect of dopamine and other catecholamines on neuromuscular transmission.
Topics: Animals; Anura; Blood Pressure; Carotid Arteries; Cats; Depression, Chemical; Dihydroxyphenylalanine | 1969 |
Peripheral neuropathy with myokymia, sustained muscular contraction, and continuous motor unit activity.
Topics: Action Potentials; Adult; Calcium; Decamethonium Compounds; Demyelinating Diseases; Edrophonium; Ele | 1972 |
Studies on the mechanism of action of dantrolene sodium. A skeletal muscle relaxant.
Topics: Acetylcholine; Aldehydes; Aniline Compounds; Animals; Anura; Caffeine; Depression, Chemical; Diaphra | 1972 |
Further observations on subacute denervation and mammalian motor nerve terminal function.
Topics: Action Potentials; Animals; Cats; Dose-Response Relationship, Drug; Edrophonium; Electric Stimulatio | 1973 |
Paralysis periodica paramyotonica. A clinical and neurophysiological study.
Topics: Acetazolamide; Acetylcholine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Cre | 1974 |
Adverse interaction between steroid hormones and anticholinesterase drugs.
Topics: Action Potentials; Animals; Anura; Cholinesterase Inhibitors; Dexamethasone; Drug Interactions; Edro | 1974 |
The diagnosis and management of myasthenia gravis.
Topics: Adrenocorticotropic Hormone; Edrophonium; Electric Stimulation; Evoked Potentials; Fingers; Humans; | 1974 |
A quantitative comparison of the antagonism of tubocurarine and diallylnortoxiferine by four anticurare agents.
Topics: Ambenonium Chloride; Animals; Cholinesterase Inhibitors; Curare; Diaphragm; Drug Antagonism; Edropho | 1967 |
Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita.
Topics: Adult; Cold Temperature; Edrophonium; Electric Stimulation; Electromyography; Facial Muscles; Fatigu | 1974 |
Muscle weakness after rest in myotonic disorders; an electrophysiological study.
Topics: Action Potentials; Adult; Edrophonium; Electric Stimulation; Electromyography; Guanidines; Humans; M | 1974 |
Comparison of the potencies of edrophonium, neostigmine and eserine with a new anticholinesterase drug RX 67668 on human tissues.
Topics: Cholinesterase Inhibitors; Colon; Cyclohexanes; Edrophonium; Humans; Ileum; In Vitro Techniques; Mus | 1973 |
Proceedings: Tetanic and single twitch responses of skeletal muscle during repeated injections of suxamethonium in man.
Topics: Drug Synergism; Edrophonium; Humans; Muscle Contraction; Succinylcholine; Thumb; Time Factors | 1973 |
The inhibitory action of dopamine on the rat anterior tibialis muscle preparation.
Topics: Animals; Anura; Chlorpromazine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Ed | 1974 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F | 1974 |
L-DOPA and dopamine on skeletal muscle.
Topics: Animals; Blood Pressure; Cats; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Edrophonium; | 1971 |
The measurement of the force of thumb adduction.
Topics: Biomechanical Phenomena; Edrophonium; Gallamine Triethiodide; Humans; Muscle Contraction; Thumb; Tra | 1969 |
The neuromuscular blocking action of suxamethonium in the anaesthetised rat.
Topics: Animals; Depression, Chemical; Drug Antagonism; Drug Synergism; Edrophonium; Gallamine Triethiodide; | 1969 |