Page last updated: 2024-10-26

edrophonium and Lupus Erythematosus, Systemic

edrophonium has been researched along with Lupus Erythematosus, Systemic in 1 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Reports on association of systemic lupus erythematosus (SLE) and myasthenia gravis are sparse."1.31[Ocular myasthenic syndrome and systemic lupus erythematosus]. ( Budde, M; Gusek-Schneider, GC; Heckmann, JG; Kraus, B, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budde, M1
Heckmann, JG1
Kraus, B1
Gusek-Schneider, GC1

Other Studies

1 other study available for edrophonium and Lupus Erythematosus, Systemic

ArticleYear
[Ocular myasthenic syndrome and systemic lupus erythematosus].
    Klinische Monatsblatter fur Augenheilkunde, 2002, Volume: 219, Issue:7

    Topics: Adult; Diplopia; Edrophonium; Female; Humans; Lupus Erythematosus, Systemic; Myasthenia Gravis; Sens

2002